Coralan: function, dosage, side effects, how to use

Functions and uses

What is Coralan for?

Coralan is a drug used to treat two main conditions, namely:

Heart failure

Heart failure is a condition in which the heart muscle does not pump blood strongly enough to flow throughout the body.

Usually this drug is prescribed to adults to help prevent heart failure from getting worse.

Apart from adults, Coralan is also often prescribed by children who have heart failure due to an enlarged heart (dilated cardiomyopathy).

When taken at the right dose, this drug will make it easier for you to breathe, less tired, and reduce swelling in your body.

Angina stable

Angina is pain or discomfort in the chest. This pain or sensation can also spread to the arms and neck. Sometimes, the pain can even spread to the shoulders and back.

Angina is usually caused when too little blood and oxygen is getting into the heart. As a result, the heart works harder at a rate of 70 beats per minute or more.

That way, Coralan helps reduce angina stable by lowering the heart rate.

How do I use Coralan?

Before drinking it, be sure to read the instructions provided by your doctor. This medicine is usually consumed by swallowing it directly with plain water or with certain foods.

If you use Coralan in liquid form, follow the instructions for use on the packaging. Try to use the measuring spoon provided in the medicine package.

Avoid using a regular spoon because the dose given can be excessive. Take this drug regularly so that the drug works optimally.

How do I save Coralan?

This medication is best stored at room temperature, away from direct light and damp places. Do not store in the bathroom and do not freeze.

Try to store Coralan at temperatures below 30 degrees Celsius, but not in the refrigerator or freezer.

Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so.

Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Dose

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage of Coralan for adults?

Dosage is usually based on your medical condition and response to treatment. However, usually the recommended dosage is one tablet in the morning and one tablet at night.

In some cases, for example if you are elderly, your doctor may prescribe a half dose which is half a 5 mg Coralan tablet in the morning and half a 5 mg tablet at night.

What is the dosage of Coralan for children?

In children, apart from medical conditions and response to treatment, drug dosage is also based on body weight.

To reduce the risk of side effects, your doctor may start this medication at a low dose and gradually increase the dose.

In what dosage is Coralan available?

Coralan is available in solution and tablet form.

Side effects

What side effects can I experience due to Coralan?

Coralan can indeed help people who have heart failure and angina stable . However, as with other medicines there are several possible effects such as:

• Vision problems such as bright spots, halos, colored flashes, or multiple images. This is especially true when images move quickly between dim and bright lighting conditions.
• Fast and irregular heartbeat
• A weakened and slowed heart rate
• Nausea
• Constipation
• Diarrhea
• Stomach ache
• Headache
• Fainting (due to slow heart rate)
• Vertigo
• Difficulty breathing
• Muscle cramp
• Feeling tired or weak
• Dizziness or lightheadedness

In addition, Coralan can also cause changes in the levels of uric acid, white blood cells, and creatinine in the blood.

However, not everyone experiences this side effect. There may be some side effects not listed above.

If you are concerned about the side effects please consult your doctor or pharmacist.

Precautions & warnings

What should be known before using Coralan?

Not everyone is allowed to use Coralan. Here's a list of people who should not use this drug:

• Have an allergy to ivabradine hydrochloride, the active substance in Coralan
• Have a heart rhythm disorder
• Has an artificial pacemaker implanted in the body
• Has a 3 degree Atrioventricular (AV) block
• Have a resting heart rate below 70 beats per minute before treatment
• Have acute heart failure
• Have angina unstable
• Have very low blood pressure
• Experiencing cardiogenic shock, which is a sudden drop in pressure and severe blood flow because the heart doesn't pump normally
• Have a heart attack
• Have severe liver disease
• Suffering from Hypertrophic Cardiomyopathy (HOCM)
• Are pregnant or trying to become pregnant
• Are in childbearing age and do not use reliable contraceptives
• Are breastfeeding

Consult a doctor for more details.

Is Coralan safe for pregnant and lactating women?

Coralan should not be consumed by pregnant and lactating women. This is because Coralan can adversely affect babies and developing fetuses.

Always consult your doctor to weigh the potential benefits and risks before using this medication.

Drug interactions

What medicines might interact with Coralan?

Interactions with other drugs can affect how the drug works and increase the risk of dangerous side effects.

This article does not list all possible drug interactions. For that, record all medicinal products you use (including prescription, non-prescription drugs, and herbs) and show them to your doctor and pharmacist.

Do not start, stop, or change the dose of any medication without your doctor's permission.

As for some drugs that can cause negative interactions, namely:

• Antibiotics from the macrolide class such as azithromycin, clarithromycin, erythromycin and roxithromycin
• Ketonacozole, an oral anti-fungal drug
• Rifampicin
• Barbiturates (for insomnia or epilepsy)
• Phenytoin (for epilepsy)
• Beta-blockers (such as atenolol, propranolol, metoprolol, etc., for high blood pressure, heart rhythm disorders, or angina pectoris)
• Quinidine, disopyramide, ibutilide, sotalol (to treat heart rhythm disorders)
• Imipramine (to treat depression)
• Phenothiazines and thioridazines for treating anxiety, schizophrenia or other psychosis
• Amiodarone (for heart rhythm disorders)
• Diltiazem
• Verapamil
• Herbal remedies such as St. John's Wort
• Frusemide
• Hydrochlorothiazide
• Indapamide

Can food or alcohol interact with Coralan?

Avoid eating or drinking grapefruit juice while using this medicine unless your doctor or pharmacist has approved it.

This is because grapefruit can increase the risk of drug side effects. For more details, ask your doctor or pharmacist.

What health conditions can interact with Coralan?

Any other health conditions you have can affect the use of this drug. Some of the conditions that can interact negatively with the drug Coralan include:

• Are using an artificial pacemaker
• Slow heart rate (less than 70 beats per minute)
• Have a condition called long QT syndrome
• Have symptoms of atrial fibrillation, a heart condition in which the resting pulse is very high (more than 110 beats per minute) or irregular for no apparent reason
• Low blood pressure
• Just had a stroke
• Have angina unstable
• Have severe heart failure
• Allergy to certain drugs and foods, dyes, or preservatives
• Have severe liver disease
• Have moderate or severe kidney disease
• Have an eye problem with retinitis pigmentosa, a condition that affects the light-sensitive cells on the inside of the eye

Overdose

What should I do in an emergency or overdose?

If a family has an emergency or an overdose of this drug, contact the local emergency services provider immediately (119). You can also go to the nearest hospital emergency room (UGD) immediately.

What should I do if I miss a dose?

If you forget a dose of this medicine, take the next dose at the hour you normally take the medicine. There is no need to double the dose of the drug to make up for the missed dose.

If you have trouble remembering to take your medicine, take it at the same time every day.