Anti-jo

Definition

What are anti-jo-1 antibodies?

The Anti-Jo-1 antibody test is used to accurately diagnose autoimmune interstitial pneumonia and advanced autoimmune myositis.

Anti Jo-1 (Antihistidyl transfer synthase) is a form of anti-extractable nuclear antigens (anti-ENA) in the human body.

Anti-Jo-1 is commonly found in people with autoimmune interstitial pneumonia and some people with advanced autoimmune inflammation. These antibodies are usually used to diagnose both diseases.

When should I take anti-jo-1 antibodies?

Your doctor will recommend testing if you have symptoms of autoimmune disease and interstitial pneumonia, and if you receive a positive result on the ANA test. Symptoms of autoimmune interstitial pneumonia are:

• You have difficulty breathing when doing strenuous work such as exercising or climbing stairs
• Over time, you may experience difficulty in daily activities such as bathing, dressing, eating and talking
• cough
• muscle aches, weight loss, fatigue
• cyanosis of the lips, skin and nails

Precautions & warnings

What should I know before taking anti-jo-1 antibodies?

Anti-Jo-1 antibodies are an important clue in diagnosing interstitial lung disease and in classifying the stage of the disease so that doctors can provide appropriate treatment. In addition, these antibodies can be used to monitor your condition and response to treatment.

It is important that you understand the warnings above before running this test. If you have any questions, consult your doctor for further information and instructions.

Process

What should I do before taking anti-jo-1 antibodies?

The doctor will explain the test process to you. This test is a blood test. You don't need to make any special preparations, apart from avoiding eating and drinking before the test.

It is recommended that you wear clothes with short sleeves to make the process of drawing blood easier.

How is the anti-jo-1 antibody process?

The medical personnel in charge of drawing your blood will take the following steps:

• wrap an elastic belt around your upper arm to stop blood flow. This makes the blood vessel under the bundle enlarge making it easier to insert the needle into the vessel
• clean the area to be injected with alcohol
• inject a needle into a vein. More than one needle may be required.
• Insert the tube into the syringe to fill it with blood
• untie the knot from your arm when enough blood is drawn
• sticking gauze or cotton on the injection site, after the injection is complete
• apply pressure to the area and then put a bandage on

What should I do after taking anti-jo-1 antibodies?

The doctor or nurse will take a sample of your blood. Pain depends on the skills of the nurse, the condition of the blood vessels and your sensitivity to pain.

After the blood draw, it is recommended that you wrap it with a bandage and apply light pressure to your vein to stop the bleeding. You can do your normal activities after the test.

If you have any questions about this test process, please consult with your doctor to understand more.

Explanation of the Test Results

What do my test results mean?

Normal result : negative.

Abnormal results : Increased antibody Jo-I:

• fibrosis of the lungs
• autoimmune myositis

Consult your doctor if you have questions about test results.