Ceftazidime: functions, dosage, side effects, how to use it

What medicine is Ceftazidime?

What is Ceftazidime for?

Ceftazidime is an antibiotic used to treat a variety of bacterial infections such as lower respiratory tract infections, urinary tract infections, meningitis, and gonorrhea. It belongs to a class of antibiotics called cpehalosporins, which work by stopping the growth of bacteria.

Ceftazidime is a drug that will not work against viral infections such as colds and flu. Using antibiotics when they are not needed can increase the risk of developing an infection that refuses later antibiotic treatment. Only use when recommended by a doctor.

How is Ceftazidime stored?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Ceftazidime dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of Ceftazidime for adults?

• Adult dosage for bacteremia

Can use a dose of 2 g infusion every 8 hours for 14 days, depending on the level of infection.

• Adult Dose for Meningitis:

Can use a dose of 2 g infusion every 8 hours for 14 days, depending on the level of infection.

• Adult Dose for Sepsis:

Can use a dose of 2 g infusion every 8 hours for 14 days, depending on the level of infection.

• Adult Dose for Endocarditis:

Can use a dose of 2 g infusion every 8 hours. Treatment may take 6 weeks or more, depending on the level of infection.

• Adult Dose for Endometritis

Can use a dose of 2 g infusion or IM every 8 hours. Parenteral therapy (injection or injection) should be continued for at least 24 hours, after which the patient remains afebrile, no pain, and the leukocyte count has become normal. Doxycline therapy for 14 days is recommended if chlamydia infection is still present in postpartum patients (breastfeeding should be stopped).

What is the dose of Ceftazidime for children?

For bacteremia in children:

• For ages 0 to 4 weeks, a birth weight of 1199 g or less, using a dosage of 30 to 50 mg / kg infusion every 12 hours.
• For ages 0 to 7 days, body weight at birth 1200 to 2000 g, can use a dose of 30 to 50 mg / kg infusion every 12 hours.
• For ages 0 to 7 days, body weight at birth 2001 g or more, can use doses of 30 to 50 mg / kg infusion every 8 to 12 hours.
• For ages 7 days to 4 weeks, weight at birth 1200 g or more, can use doses of 30 to 50 mg / kg infusion every 8 to 12 hours.
• For ages 1 month to 12 years: 30 to 50 mg / kg infusion every 8 hours the maximum dose is 6 g / day

Whereas for ages 13 years or more, adult dosages can be used

Higher doses are given to patients with meningitis, cystic fibrosis, or patients with weakened immune systems.

For cystitis in children:

• For ages 0 to 4 weeks, weight at birth 1199 g or less: 30 to 50 mg / kg infusion every 12 hours
• For ages 0 to 7 days, weight at birth 1200 to 2000 g: 30 to 50 mg / kg infusion every 12 hours
• For ages 0 to 7 days, weight at birth 2001 g or more: 30 to 50 mg / kg infusion every 8 to 12 hours
• For 7 days to 4 weeks, birth weight 1200 g or more: 30 to 50 mg / kg infusion every 8 to 12 hours
• For ages 1 month to 12 years: 30 to 50 mg / kg infusion every 8 hours the maximum dose is 6 g / day

For ages 13 years or more, adult dosages can be used

Higher doses are given to patients with meningitis, cystic fibrosis, or patients with weakened immune systems.

For intraabdominal infections in children:

• For ages 0 to 4 weeks, weight at birth 1199 g or less can use a dose of 30 to 50 mg / kg infusion every 12 hours
• For ages 0 to 7 days, weight at birth 1200 to 2000 g can use a dose of 30 to 50 mg / kg infusion every 12 hours
• For ages 0 to 7 days, body weight at birth 2001 g or more can use a dose of 30 to 50 mg / kg infusion every 8 to 12 hours
• For 7 days to 4 weeks, birth weight of 1200 g or more can use a dose of 30 to 50 mg / kg infusion every 8 to 12 hours.
• For ages 1 month to 12 years can use a dose of 30 to 50 mg / kg INFUS every 8 hours the maximum dose is 6 g / day

Age 13 years or older can use adult doses. Higher doses are given to patients with meningitis, cystic fibrosis, or patients with a weakened immune system.

In what dosage is Ceftazidime available?

Ceftazidime is a drug that is available in the following dosage forms:

• Solution for intravenous (infusion): 1 g, 2g
• Solution for injection: 1 g, 2g, and 6 g

Ceftazidime side effects

What side effects can be experienced due to Ceftazidime?

Seek medical help immediately if you experience signs of an allergic reaction to this medicine: hives difficulty breathing swelling of the face, lips, tongue, or throat.

Immediately call your doctor if there are serious side effects such as:

• Diarrhea that is watery or bloody
• Swelling, pain, or irritation where the injection is given
• A feeling of coldness, discoloration, or skin changes on your fingers
• Seizures
• White areas or canker sores in your mouth or on your lips
• Yellow color to the skin or eyes
• Severe skin reaction - fever, sore throat, or swelling of the face or tongue, burning feeling in the eyes, sore skin, followed by a red or purple rash that spreads (especially on the face or upper body) and causes blistering and peeling

Mild side effects include:

• Nausea, vomiting, diarrhea, stomach pain
• Headache, dizziness
• Numbness or tingling or
• Vaginal itching or vaginal discharge

Not everyone experiences the above side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Ceftazidime Drug Warnings and Cautions

What should be known before using Ceftazidime?

Do not use this medication if you have an allergy to ceftazidime, or a similar antibiotic, such as:

• Cefaclor (Ceclor)
• Cefadroxil (Duricef)
• Cefazolin (Ancef)
• Cefdinir (Omnicef)
• Cefditoren (Spectracef)
• Cefprozil (Cefzil)
• Ceftibuten (Cedax)
• Cefuroxime (Ceftin)
• Cephradine (Velosef)
• Cephalexin (Keflex) and others

To determine whether you can use ceftazidime safely, tell your doctor if you have any of these conditions:

• Kidney illness
• Liver disease
• Stomach or intestinal disorders such as colitis
• Diabetes
• Congenital heart failure
• If you have an allergy to penicillin
• Cancer
• If you are malnourished
• If you have recently had surgery or a medical emergency

Is Ceftazidime safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category B according to the US Food and Drug Administration (FDA).

The following references the pregnancy risk categories according to the FDA:

• A = Not at risk
• B = No risk in several studies
• C = May be risky
• D = There is positive evidence of risk
• X = Contraindicated
• N = Unknown

Ceftazidime Drug Interactions

What medicines may interact with Ceftazidime?

Ceftazidime is a drug that can interact if you have certain conditions. The presence of other health problems can affect the use of this drug. Tell your doctor if you have other health problems, especially:

Use of this medication with the following drugs is usually not recommended, but may be required in some cases. If the two medicines are prescribed together, your doctor may adjust the dose or how often you should use one or both drugs.

• Warfarin

Using this medicine with the medicines below may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If the two medicines are prescribed together, your doctor may adjust the dose or how often you should use one or both drugs.

• Chloramphenicol

Can food or alcohol interact with Ceftazidime?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions may interact with Ceftazidime?

The presence of other health problems can affect the use of this drug. Tell your doctor if you have other health problems, especially:

• Brain disease (example: encephalopathy, severe confusion)
• Colitis (inflammation of the intestines), or history
• Diarrhea, severe diarrhea, history
• Myoclonus (muscle spasms)
• Seizures - use with care. can make the condition worse
• Kidney disease - use with caution. The effect may increase due to slower removal of the drug from the body

Ceftazidime overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.