Ganirelix: functions, dosage, side effects, how to use

Use

What is Ganirelix for?

Ganirelix, also known as ganirelix acetate, is an injectable drug used to treat fertility problems in women.

Ganirelix is ​​generally combined with other hormone drugs (FSH and hCG). Ganirelix works by inhibiting the release of certain hormones (luteinizing hormone or LH). This helps delay ovulation and increases the chances of producing fertile eggs.

What are the rules for using Ganirelix?

The way of giving Ganirelix medicine is by injecting it under the skin (subcutaneous). Follow the rules for using injection or injection drugs that have been given by your doctor.

Here are some things you should pay attention to about how to use Ganirelix:

• Before using injectable drugs, wash your hands with soap and water before using this medicine. Then, clean the area of ​​the skin that will be injected with alcohol.
• It is important to change the location of the injection every day to avoid discomfort or problems under the skin.
• Inject the dose prescribed according to the doctor's instructions. Discard any unused portion of the drug immediately after injection. Don't save it for future use.
• Do not use this medication for more than the recommended dose, for less, or for longer than the recommended dosage.
• Learn how to safely store and dispose of injections, syringes and medical supplies. Consult your pharmacist for more information.

How to store this drug?

Store Ganirelix at room temperature away from light and moisture. Do not store in the bathroom and freeze medication.

Medicines under different brands may have different storage methods. Check the product box for instructions on how to store it, or ask the pharmacist. Stay away from children and pets.

It is forbidden to flush the medicine in the toilet or throw it into the drain if not told to. Discard this product when the drug has expired or when it is no longer needed.

Consult your pharmacist or local waste disposal agency about how to safely dispose of your medicine.

Dose

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the Ganirelix dosage for adults?

To prevent the release of luteinizing hormone (LH) during controlled ovarian hyperstimulation: 0.25 mg under the skin once daily.

Ganirelix is ​​most comfortable to apply to the abdomen around the navel or upper thighs. Generally, exogenous follicle stimulating hormone (FSH) is started on day 2 or 3 of the natural menstrual cycle.

Ganirelix is ​​given at the start of day 7 or 8 (day 6 of FSH treatment). Ganirelix therapy is continued until adequate follicle maturation, at which time human chorionic gonadotropin (hCG) is administered.

What is the Ganirelix dosage for children?

The dosage for children has not been determined. Consult your doctor for more information.

In what dosage and preparation is Ganirelix available?

Solution, under the skin, as acetate: 250 mcg / 0.5 mL (0.5 mL)

Side effects

What side effects may occur due to Ganirelix?

If you experience a severe (anaphylactic) allergic reaction to this medicine, seek medical attention immediately. Symptoms of an allergic reaction can include:

• Itchy rash
• Difficulty breathing
• Swelling of the face, lips, tongue, or throat

According to Drugs.com, some women taking this drug are reported to have the condition ovarian hyperstimulation syndrome (OHSS). This condition is generally seen after the first treatment cycle. OHSS can be a life threatening condition.

Contact your doctor as soon as possible if you experience the following OHSS symptoms:

• Pelvic pain is excruciating
• Swollen hands or feet
• Stomach pain and swelling
• Shortness of breath
• Weight gain
• Diarrhea
• Nausea or vomiting or
• Less urination.

Milder side effects may include:

• Pelvic pain (similar to menstrual cramps)
• Nausea or mild stomach pain
• Headache
• Vaginal bleeding or
• Pain, redness, or irritation at the injection site.

Not everyone experiences the following side effects. There may be some side effects not listed above.

If you have concerns about certain side effects, consult your doctor or pharmacist.

Precautions & Warnings

What should be known before using Ganirelix?

All medications have warnings and risks that are important for you to learn about. Here are some things you need to pay attention to before using Ganirelix:

• You should not use this medication if you have a history of allergies to certain drugs, especially Ganirelix or similar drugs such as leuprolide (Lupron, Eligard), goserelin (Zoladex), or nafarelin (Synarel).
• Before using Ganirelix, tell your doctor if you are allergic to rubber latex.
• Tell your doctor about any medications you are currently using, whether prescription, non-prescription, supplements, or herbal medicines. This is because several types of drugs may interact with Ganirelix.
• In addition, it is also important to inform your doctor about any diseases or other health conditions that you are currently suffering from. It is possible that this drug can trigger interactions with certain diseases or health conditions.

Is this drug safe for pregnant or breastfeeding women?

This drug is included in the risk of pregnancy category X, aka contraindications. This means that Ganirelix should not be used by pregnant women.

There are not sufficient studies in women to determine infant risk if using this medicine during breastfeeding. Consider the possible risk-fighting benefits before using this medication while breastfeeding.

Interaction

What medicines may interact with Ganirelix?

Although certain drugs are completely prohibited from being used at the same time, in other cases two different drugs can be used simultaneously even though interactions may occur.

In this case, the doctor may want to change the dose, or other warnings may be important. Tell your healthcare professional if you are on prescription or nonprescription drugs.

Can food or alcohol interact with Ganirelix?

Certain drugs should not be used when eating certain foods because drug-food interactions can occur.

Smoking tobacco or consuming alcohol with certain drugs can also cause interactions to occur.

Discuss your use of drugs with food, alcohol, or tobacco with your doctor, medical team, or pharmacist.

What health conditions may interact with Ganirelix?

The presence of other medical disorders may affect the use of this drug. Make sure you tell your doctor if you have any other medical problems, especially: women with active allergic conditions or a history of allergies.

Overdose

What should I do in an emergency or overdose?

In case of an emergency or symptoms of an overdose, contact the local emergency services provider (118 or 119) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Avoid doubling the dose of the drug in one use.

Hello Health Group does not provide medical advice, diagnosis or treatment.