Human albumin: function, dosage, side effects, how to use it

What Drug Human Albumin?

What is human albumin for?

Human Albumin is used to treat decreased blood volume (hypovolemia) caused by an emergency situation where the patient is suffering from active or critical bleeding. Sudden loss of large amounts of blood can cause the body to go into shock and be life threatening.

Human albumin is a plasma protein concentrate made from human blood. Albumin works by increasing the plasma volume or serum albumin level.

How do you use human albumin?

Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

Use human albumin as directed by your doctor. Check the label on the medicine for precise dosing instructions.

Human albumin is usually given as an injection at a doctor, hospital, or clinic. If you are using human albumin at home, carefully follow the injection procedures taught by your healthcare provider.

If the human albumin appears to contain foreign particles or is discolored, or if the bottle is cracked or damaged, do not use it.

Use human albumin with the included administration tools. Make sure a filter is used. Once opened, administration must begin within 4 hours. Discard bottles that have been open for more than 4 hours. Don't save the bottle for later use.

Do not inject human albumin sooner than the time prescribed by your doctor.

Ask your doctor any questions you have about how to use human albumin.

How do you store human albumin?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Human Albumin Dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the human albumin dosage for adults?

The usual adult dosage for peritonitis
Albumin 5%:

Initial dose: 250/500 mL IV at a rate of 1 - 2 mL / min in the absence of shock. The administration set capacity is the only limit in patients who are deprived of blood. The infusion rate and the total volume to be administered are determined by the patient's condition and response. The initial dose may be followed by additional albumin within 15-30 minutes if the response is inadequate.

Albumin 25%:
Initial dose: Patients may need 200 - 300 mL IV to reduce edema and bring serum protein levels back to normal. Because patients usually have near normal blood volumes, doses of more than 100 mL for 25% albumin should not be given sooner than 100 mL IV over 30 to 45 minutes to avoid circulatory overload. If slower administration is desired, 200 mL of 25% albumin can be mixed with 300 mL of 10% dextrose solution and controlled at an IV rate of 100 mL per hour.

The usual adult dosage for shock
Albumin 5%:
Initial dose: 250/500 mL IV at a rate of 1 - 2 mL / min in the absence of shock overt. The administration set capacity is the only limit in patients who are deprived of blood. The infusion rate and the total volume to be administered are determined by the patient's condition and response. The initial dose may be followed by additional albumin within 15-30 minutes if the response is inadequate.

Albumin 25%:
Initial dose: Patients may need 200 - 300 mL IV to reduce edema and bring serum protein levels back to normal. Because these patients usually have near-normal blood volumes, doses of more than 100 mL of 25% albumin should not be given sooner than 100 mL IV over 30 to 45 minutes to avoid circulatory overload. If slower administration is desired, 200 mL of 25% albumin can be mixed with 300 mL of 10% dextrose solution and controlled at an IV rate of 100 mL per hour.

The usual adult dosage for pancreatitis
Albumin 5%:
Initial dose: 250/500 mL IV at a rate of 1 - 2 mL / min in the absence of shock overt. The administration set capacity is the only limit in patients who are losing blood. The infusion rate and the total volume to be administered are determined by the patient's condition and response. The initial dose may be followed by additional albumin within 15-30 minutes if the response is inadequate.

Albumin 25%:
Initial dose: Patients may need 200 - 300 mL IV to reduce edema and bring serum protein levels back to normal. Because these patients usually have near-normal blood volumes, doses of more than 100 mL of 25% albumin should not be given sooner than 100 mL IV over 30 to 45 minutes to avoid circulatory overload. If slower administration is desired, 200 mL of 25% albumin can be mixed with 300 mL of 10% dextrose solution and controlled at an IV rate of 100 mL per hour.
Usual adult dose for external burns
Albumin 5%:
Initial dose: 250/500 mL IV at a rate of 1 - 2 mL / min in the absence of shock overt. The administration set capacity is the only limit in patients who are losing blood. The infusion rate and the total volume to be administered are determined by the patient's condition and response. The initial dose may be followed by additional albumin within 15-30 minutes if the response is inadequate.

Albumin 25%:
Initial dose: Patients may need 200 - 300 mL IV to reduce edema and bring serum protein levels back to normal. Because these patients usually have near normal blood volumes, doses of more than 100 mL of 25% albumin should not be given sooner than 100 mL IV over 30 to 45 minutes to avoid circulatory overload. If slower administration is desired, 200 mL of 25% albumin can be mixed with 300 mL of 10% dextrose solution and controlled at an IV rate of 100 mL per hour.


The usual adult dosage for Hypoproteinemia
Albumin 5%:
Initial dose: 250/500 mL IV at a rate of 1 - 2 mL / min in the absence of shock overt. The administration set capacity is the only limit in patients who are losing blood. The infusion rate and the total volume to be administered are determined by the patient's condition and response. The initial dose may be followed by additional albumin within 15-30 minutes if the response is inadequate.

Albumin 25%:
Initial dose: Patients may need 200 - 300 mL IV to reduce edema and bring serum protein levels back to normal. Because these patients usually have near normal blood volumes, doses of more than 100 mL of 25% albumin should not be given sooner than 100 mL IV over 30 to 45 minutes to avoid circulatory overload. If slower administration is desired, 200 mL of 25% albumin can be mixed with 300 mL of 10% dextrose solution and controlled at an IV rate of 100 mL per hour.

Usual adult dose for postoperative albumin loss

Albumin 5%:
Initial dose: 250/500 mL IV at a rate of 1 - 2 mL / min in the absence of shock overt. The administration set capacity is the only limit in patients who are losing blood. The infusion rate and the total volume to be administered are determined by the patient's condition and response. The initial dose may be followed by additional albumin within 15-30 minutes if the response is inadequate.

Albumin 25%:
Initial dose: Patients may need 200 - 300 mL IV to reduce edema and bring serum protein levels back to normal. Because these patients usually have near-normal blood volumes, doses of more than 100 mL of 25% albumin should not be given sooner than 100 mL IV over 30 to 45 minutes to avoid circulatory overload. If slower administration is desired, 200 mL of 25% albumin can be mixed with 300 mL of 10% dextrose solution and controlled at an IV rate of 100 mL per hour.

What is the dose of human albumin for children?

Usual child dosage for peritonotid
Albumin 5%:

Initial dose: 10-15 mL IV per lb of body weight (4.5-6.8 mL per kg), usually with close supervision.

Typical children's dosage for shock
Albumin 5%:

Initial dose: 10-15 mL IV per lb of body weight (4.5-6.8 mL per kg), usually with close supervision.

Usual children's dosage for pancreatitis
Albumin 5%:

Initial dose: 10 to 15 mL per pound (4.5-6.8 mL per kg) of body weight IV is usually adequate accompanied by close supervision of the child.


Typical children's dosage for external burns
Albumin 5%:

Initial dose: 10-15 mL IV per lb of body weight (4.5-6.8 mL per kg), usually with close supervision.

Typical children's dosage for Hypoproteinemia
Albumin 5%:

Initial dose: 10-15 mL IV per lb of body weight (4.5-6.8 mL per kg), usually with close monitoring.

Usual child dosage for postoperative loss of albumin
Albumin 5%:

Initial dose: 10-15 mL IV per lb of body weight (4.5-6.8 mL per kg), usually with close monitoring.

In what dosage is human albumin available?

Human Albumin is available in the following dosages:

Solution, intravenous injection: 5% (50 mL), 25% (50 mL, 100 mL)

Human Albumin side effects

What side effects can be experienced due to human albumin?

All drugs can have side effects, but many people have few or few side effects. When used in small doses, no GENERAL side effects have been reported regarding human albumin. Seek medical care immediately if any of the serious side effects develop a severe allergic reaction (rash; hives, itching, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue); changes in heart rate or breathing; chills; confusion; excess saliva; passed out; fever; headache; nausea; gag; weakness.

Not everyone experiences this side effect. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Human Albumin Drug Warnings and Cautions

What should be known before using human albumin?

Before using Human Albumin, contact your doctor if:

• You are allergic to ingredients contained in human albumin
• You have or have a stable history of heart failure, kidney failure or anemia, or you are at risk of fluid overload

Is human albumin safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug falls into pregnancy risk category C according to the US Food and Drug Administration (FDA).

The following references the pregnancy risk categories according to the FDA:
• A = no risk
• B = no risk in some studies
• C = there may be some risks
• D = positive evidence of risk
• X = contraindicated
• N = unknown

It is not known whether this drug passes into breast milk. Human albumin is given to nursing mothers only when needed. Because many drugs are absorbed into breast milk, caution and precautions should be taken with caution when giving human albumin to pregnant women.

Human albumin drug interactions

What drugs might interact with human albumin?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

The albumin solution should not be mixed with protein hydrolyzates or alcoholic solutions. Risk of atypical reactions with ACE inhibitors in patients undergoing plasma exchange therapy with human albumin replacement.

Can food or alcohol interact with human albumin?

Certain drugs should not be used with meals or around meals at certain foods or foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with human albumin?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

• if you are pregnant, planning to become pregnant, or are breastfeeding
• if you are on prescription or nonprescription drugs, herbal preparations, or dietary supplements
• if you have an allergy to drugs, food, or other substances
• hypertension or low cardiac reserve

Human Albumin overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.