Metrix: function, dosage, side effects, how to use

Use

What is Metrix for?

Metrix is ​​an oral drug that functions to reduce blood sugar levels in the body of type two diabetes patients. This drug is given if diet, physical exercise, and weight loss programs are unable to control sugar levels in the body. The use of this drug combined with a proper diet and exercise program can help type 2 diabetes patients avoid kidney damage, nerve problems, blindness, loss of limbs, and problems with sexual function. Proper blood sugar control can also help people with diabetes (diabetes) reduce their risk of having a heart attack and stroke.

Metrix is ​​a trademark of the generic drug glimepiride. Glimepiride itself is included in the sulfonylurea class of treatment. Glimepiride in Metrix works by encouraging the release of insulin produced by the pancreas and increasing the body's sensitivity to insulin response.

Metrix is ​​intended for patients who are not dependent on insulin. That is, this drug is not intended for blood sugar control in patients with type one diabetes, who must rely on daily insulin injections to keep their blood sugar levels normal. Metrix also cannot be used as a treatment for diabetic ketoacidosis patients.

Glimepiride contained in Metrix is ​​effective for use as initial therapy in diabetic patients. If blood sugar control has not achieved the desired results after administration of this drug, combination with metformin may give better results.

What are the rules for drinking Metrix?

Follow your doctor's instructions carefully when taking this medicine. Metrix is ​​an oral medication that is taken by mouth together with a small amount of drinking water.

This medicine must be taken at the same time as food. Take Metrix at the same time as breakfast or the first meal of the morning. Usually, this medicine is given once a day.

Your doctor may give you a low dose at the start of treatment to minimize the risk of side effects. Increasing the dose can be done gradually according to your body's tolerance level.

Tell your doctor if you have also been taking other oral diabetes medications or insulin. This allows your doctor to better plan when prescribing Metrix. Follow your doctor's directions on how to stop or continue your old medication and start taking Metrix.

Take this medication as directed by your doctor. Do not change the dose or stop medication even if you feel better without consulting your doctor. The dosage given takes into account your health condition, your body's response to treatment, and the products you consume.

Take this medicine regularly for the desired results. To make it easier for you to remember, take this medication at the same time each day as the first meal of the day. If your condition does not improve, even gets worse, contact your doctor immediately to make a dosage adjustment.

What are the Metrix storage rules?

This medication is best stored at room temperature, no more than 30 degrees Celsius. Avoid storing this medication in a place exposed to direct sunlight and heat. Do not store this medication in damp places, such as the bathroom or near a sink. Read the storage instructions listed on the medicine packaging. Keep out of reach of children and pets.

Do not flush medications down the toilet or down the drain unless instructed to do so. Discard this product when it has reached its expiration date or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Dose

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage of Metrix for adults?

Initial dose: 1 mg, once a day

The recommended dosage range for patients who have good diabetes control: 1 - 4 mg per day. Only a few patients benefit from using Metrix at doses above 6 mg.

Maximum daily dose: 8 mg

What is the dosage of Metrix for children?

Dosage and administration for pediatric patients have not been established.

In what dosages and preparations is Metrix available?

Tablet, Oral: 1 mg, 2 mg, 3 mg, 4 mg

Side effects

What side effects may arise due to consumption of Metrix?

Nausea and abdominal pain may result from ingestion of the glimepiride contained in Metrix. If the condition persists and even gets worse, contact your doctor immediately.

Remember that doctors prescribe certain medications because their benefits outweigh the risk of possible side effects. Almost all drugs have side effects, but many of them are not serious. Some of the serious side effects that can occur due to consumption of Metrix are:

• Symptoms of liver function damage, which is characterized by jaundice (yellowing of the skin and eyes), nausea / vomiting, loss of appetite
• Thick colored urine, fever, confusion, or weakness
• Hypersensitive skin reaction characterized by fever, sore throat, swelling of the face or tongue, burning eyes, a reddish or purplish rash that spreads (especially on the face and upper body), and peeling skin

Hypoglycemia can also occur as a result of taking this drug. Signs include trembling, chills, chills, dizziness, blurred vision, seizures, and loss of consciousness.

Stop treatment and immediately consult your doctor if you find the above symptoms that don't go away or even get worse. Not everyone experiences the above side effects. There may also be side effects not mentioned above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Warnings and Precautions

What should I know before taking Metrix?

• Before taking this medication, tell your doctor if you have any allergies to glimepiride, sulfonylureas, or any other medications. Metrix may contain other ingredients that can cause allergies. Also inform your doctor about any other allergies you have, such as allergies to food or certain conditions
• Tell your doctor about your medical history, including past and current illnesses, especially heart disease, liver disease, kidney disease or undergoing dialysis, thyroid gland disorders, certain hormonal conditions, glucose-6-phosphate enzyme deficiency. dehydrogenase (an inherited condition that causes the rapid breakdown of red blood cells)
• You may experience visual disturbances, weakness, and drowsiness due to changes in blood sugar levels at the beginning of taking this drug. Do not engage in activities that require high alertness, such as driving, after taking Metrix before knowing how your body responds to this drug.
• If you are going to have surgery, including dental surgery, tell your doctor or dentist about using Metrix (glimepiride).
• Tell your doctor all the products you use, including nonprescription drugs, vitamins, and herbal medicines. Some products may interact to decrease how the drug works. A list of interactions can be seen in the next section
• Tell your doctor if you are planning a pregnancy or are pregnant and need blood sugar control. The use of this drug in pregnant women is only permitted when absolutely necessary. Your doctor may provide alternative treatment

Is Metrix safe for pregnant and lactating women?

Based on studies conducted on animals, administration of this drug indicates a risk to the fetus. However, there has not been adequate research regarding the risks of using this drug in pregnant or breastfeeding women. Talk to your doctor about giving this drug during pregnancy. Switching to insulin to control blood sugar may be a good option. Metrix is ​​included in the category C pregnancy risk (possibly risky) according to the United States Food and Drug Administration.

Drug Interactions

Drug Interactions

What drugs may interact with Metrix?

Certain drugs cannot be prescribed together because they may cause drug interactions. Drug interactions can change how one drug works or increase the risk of side effects. The following are some of the drugs that may interact with Metrix:

• Insulin and other diabetes drugs
• ACE inhibitors
• Allopurinol
• Anabolic steroids and testosterone
• Chloramphenicol
• Cyclophosphamide
• Disopyramide
• Fenyramidol
• Fibrates
• Fluoxetine
• Guanethidine
• Miconazole
• Ifosfamide
• Aminosalicylic acid
• Phenylbutazone
• Azapropazone
• Oxyphenbutazone
• Probenecid
• Quinolones
• Salicylates
• Sulfonamides
• Tetracycline
• Tritoqualine
• Acetazolamide
• Barbiturates
• Corticosteroids
• Diazoxide
• Diuretic
• Epinephrine and other sympathomimetic drugs
• Glucagon
• Laxative
• Estrogens and progesterone
• Phenytoin
• Rifampicin
• Thyroid hormone
• Betablockers, such as metoprolol, propanolol, timolol

The above list is not a complete list of drugs that may interact with Metrix. Keep a list of all medications you have or are currently taking and keep your doctor informed, including prescription / nonprescription drugs, herbal remedies, and vitamins.

Overdose

What should I do if I overdose on Metrix?

Hypoglycemia can result from consuming too much glimepiride. Symptoms can include decreased consciousness or tremors. The first aid that can be given to overdose patients who experience hypoglycemia is oral glucose administration (can give honey, sugar, or candy). Immediately call for emergency medical assistance (119) or the emergency department of the nearest hospital in an emergency.

What if I forget my medication schedule?

If you forget your scheduled medication, take it as soon as you remember it along with your meal. If the distance is too close to the next schedule, ignore the missed dose and continue taking the medication on the original schedule. Do not double your dose on a single medication schedule.