Pyridoxine: functions, dosage, side effects, how to use

What Drug Pyridoxine?

What is Pyridoxine for?

Pyridoxine is vitamin B6. Vitamins found in foods such as meat, poultry, nuts, wheat, bananas and avocados. Vitamin B6 plays an important role for various processes in the body.

Pyridoxine is used to treat or prevent vitamin B6 deficiency. This drug also treats certain types of anemia (lack of red blood cells). Pyridoxine injection can also be used in treating convulsions in babies.

Pyridoxine can be taken without a prescription. Pyridoxine injection must be given by a health care professional.

Pyridoxine can also be used for other purposes not listed in this medical guide.

How to use Pyridoxine?

Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

Follow all directions on the label. Do not use this medication in amounts that are large or for a little or longer than recommended.

Pyridoxine tablets can be taken by mouth. Meanwhile, pyridoxine injection is injected into a muscle or vein through an IV. You may be shown how to administer the injection yourself at home. Do not inject this medication yourself if you do not understand how the injection is administered and know how to safely dispose of used needles and IV tubes and other objects used while injecting the drug.

The recommended nutrient intake for pyridoxine increases with age. Follow your doctor's instructions. You can also consult the Office of Dietary Supplements of the National Institutes of Health, or the U.S. Department of Agriculture (USDA) Nutrient Database (formerly known as daily nutritional intake recommendations) for more detail.

Pyridoxine is only part of a complete treatment program which includes a special diet. It is very important to always have a diet plan that has been developed by your doctor or nutritionist. You should become familiar with the list of foods you should eat and avoid to help control your condition.

How is Pyridoxine stored?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Pyridoxine dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the Pyridoxine dosage for adults?

Standard adult dosage for induction of vitamin / mineral deficiency drugs

Neuritis drug induction:

Cycloserine: 100 to 300 mg / day orally in divided doses

Isoniazid or penicillamine: 100 to 200 mg / day orally for 3 weeks or 25 to 100 mg / day for prophylaxis.

Oral contraceptives: 25 to 30 mg / day.

Acute intoxication

Hydralazine: 25 mg / kg. One third of the dose is given by IM and the remainder is given as an IV infusion over 3 hours.

Isoniazid: 1 to 4 grams IV as a starting dose, then 1 g IM every 30 minutes until the required total dose has been given (given with other anticonvulsants as needed). The total dose given must be the same as the amount of isoniazid injected.

Consumption of mushrooms (genus Gyromitra): 25 mg / kg IV infused for 15 to 30 minutes. Repeat as needed with a maximum total daily dose of 15 to 20 g.

Standard adult dosage for nutritional supplements:

Pyridoxine drawbacks:

10 to 25 mg / day by mouth, IM, or IV for 3 weeks followed by 2 to 5 mg / day of a multivitamin product

Standard adult dosage for anemia

Sideroblastic, offspring: 200 to 600 mg taken daily. If an adequate response is obtained, the dose may be reduced to 30 to 50 mg orally daily.

If response is not obtained after 1 to 2 months of pyridoxine treatment, a different treatment needs to be considered.

Standard adult dose for nausea / vomiting

Nausea and vomiting due to pregnancy:

25 mg taken every 8 hours.

What is the dosage of Pyridoxine for children?

Standard pediatric dosage for induction of vitamin / mineral deficiency drugs

Induction neuritis drugs (cycloserine, isoniazid, hydralazine, penicillamine):

Treatment: 10 to 50 mg / day

Prophylaxis: 1 to 2 mg / kg / day

Acute intoxication:

Hydralazine: 25 mg / kg: one third of the dose given by IM and the rest as an IV infusion over 3 hours.

Isoniazid: acute digestion of known amounts: initial: total pyridoxine dose equivalent to a given dose of isoniazid (maximum dose: 70 mg / kg, up to 5 g); given in a range of 0.5 to 1 g / min until the seizures have stopped or the maximum initial dose has been given; can be repeated every 5 to 10 minutes as needed to control convulsions and / or CNS toxicity. If the seizures stop before the initial dose, give the remaining pyridoxine intravenously for 4 to 6 hours. Acute digestion without known amounts: initial: 70 mg / kg (maximum dose: 5 g); administered at a rate of 0.5 to 1 g / min; can be repeated every 5 to 10 minutes as needed to control convulsions and / or CNS toxicity.

Consumption of mushrooms (genus Gyromitra): 25 mg / kg IV. Repeat as needed up to a maximum total dose of 15 to 20 g.

Standard pediatric dosages for nutritional supplements

Pyridoxine drawbacks:

5 to 25 mg / day by mouth, IM, or IV for 3 weeks followed by 1.5 to 2.5 mg / day of a multivitamin product.

Standard pediatric dosage for convulsions

Pyridoxine- convulsions:

10 to 100 mg PO, IM, or IV initially, followed by 2 to 100 mg orally daily.

In what dosage is Pyridoxine available?

Pyridoxine side effects

What side effects can be experienced due to Pyridoxine?

All medicines can cause side effects, but many people do not experience or experience side effects that are not serious. When used in low doses, no side effects have been reported with this product. Seek medical attention if serious side effects occur:

Severe allergic reaction (rash; hives; difficulty breathing; tightness in the chest; swelling in the mouth, face, lips, or tongue); decreased ability to sense touch, temperature, or vibration; loss of balance; numbness in the legs or around the mouth; numbness or tingling of the skin.

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Pyridoxine Drug Warnings and Cautions

What should be known before using Pyridoxine?

Several medical conditions can interact with pyridoxine (vitamin B6 extended-release tablet). Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following has happened to you:

• If you are pregnant, planning to become pregnant, or are breastfeeding
• If you are using prescription or nonprescription drugs, herbal medicines, or nutritional supplements
• If you have allergies to drugs, food, or other substances.

Is Pyridoxine safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA). The following references the pregnancy risk categories according to the FDA:

A = No risk, B = not at risk in several studies, C = May be risky, D = There is positive evidence of risk, X = Contraindicated, N = Unknown

Pyridoxine Drug Interactions

What medicines may interact with Pyridoxine?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Some medications can interact with pyridoxine (vitamin B6 extended-release tablets). Tell your doctor if you are taking any other medications, especially any of the following:

• Hydantoins (for example, phenytoin) or levodopa because they can reduce the effectiveness of pyridoxine (vitamin B6 extended-release tablet).

This is not a complete list of possible interactions. Ask your doctor if pyridoxine (vitamin B6 extended-release tablet) might interact with other medications you are taking. Check with your doctor before you start, stop, or change the dose of medication.

Can food or alcohol interact with Pyridoxine?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions may interact with Pyridoxine?

The presence of other health problems in your body may affect the use of this drug. Tell your doctor if you have other health problems.

Pyridoxine overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

Symptoms of overdose include: numbness in the hands and feet.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.