Rabeprazole: functions, dosage, side effects, how to use

What Drug Rabeprazole?

What is rabeprazole for?

Rabeprazole is a drug used to treat certain stomach and esophageal problems (such as acid reflux, stomach ulcers). This medication works by reducing the amount of acid in your stomach. This medication relieves symptoms such as stomach ulcers, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent esophageal cancer. Rabeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).

How is rabeprazole used?

Read the drug's guide and the Patient Information Leaflet provided by the pharmacy, if available, before you get this medication and each time you buy it again. If you have questions, ask your doctor or pharmacist.

If you are taking it in tablet form, take your dose by mouth with or without food as directed by your doctor, usually 1 to 2 times daily. Swallow the tablet whole with water. Do not crush, chew, or cut the tablets. Doing so can release all of the drug at once, and increases the risk of side effects.

If you are taking capsules, take them 30 minutes before meals as directed by your doctor, usually once daily. Do not swallow the capsule whole. Open the capsule and sprinkle the contents onto a small amount of soft food (such as applesauce or yogurt) or liquids. The food or liquids you use should be at or below room temperature. Swallow the whole mixture within 15 minutes of preparation. Do not chew or crush the prepared mixture.

The dosage and length of treatment are based on your medical condition and response to treatment. In children, dosage is also based on body weight.

If needed, antacids can be taken along with this medicine. If you are also taking sucralfate, take Rabeprazole at least 30 minutes before sucralfate.

Use this remedy regularly for optimal benefits. You need to remember to take the medicine at the same time every day. Continue to use this medication for the prescribed long-term treatment even if you feel your condition is getting better.

Tell your doctor if your condition persists or gets worse.

How is rabeprazole stored?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product

Rabeprazole dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of rabeprazole for adults?

Normal dosage for adults with ulcers

Drink 20 mg once a day, after breakfast. The normal duration of therapy is four weeks in most patients, however, some patients may require additional therapy to achieve ulcer healing.

Normal Dosage for Adults with Erosive Esophagitis

20 mg taken by mouth once a day, after breakfast. Therapy should be continued for 4 to 8 weeks.

Normal Dosage for Adults with Ulcer

20 mg taken by mouth once a day, after breakfast. Therapy should be continued for 4 to 8 weeks.

Normal Dosage for Adults with Prophylactic Ulcers

20 mg taken by mouth once a day, after breakfast. Studies assess maintenance therapy for duodenal ulcers not beyond 12 months.

Normal Dosage for Adults with Gastroesophageal Reflux

20 mg taken by mouth once a day, after breakfast. Therapy should be continued for 4 to 8 weeks.

Maintenance therapy may be required in some patients as part of relapsing erosive esophagitis or unusual ulcerative gastroesophageal reflux disease. Studies have shown Rabeprazole 20 mg taken by mouth once daily for 52 weeks to provide 86% to 90% maintenance cure.

Normal dosage for adults with Helicobacter pylori infection

A three-drug regimen: Rabeprazole 20 mg, amoxicillin 1000 mg, and clarithromycin 500 mg orally twice daily with breakfast and dinner for 7 days.

In a triple therapy study, Rabeprazole 20 mg combined with clarithromycin 500 mg and metronidazole 400 mg, or amoxicillin 1000 mg and clarithromycin 500 mg, or amoxicillin 1000 mg and metronidazole 400 mg given directly twice daily for 7 days. This combination resulted in disease eradication rates of 100%, 95%, and 90%, respectively.

In a dual therapy study, Rabeprazole 20 mg combined with clarithromycin 500 mg orally twice daily for 7 days showed a 63% eradication rate.

Normal Dosage for Adults with Zollinger-Ellison Syndrome

Initial: 60 mg orally once a day, after breakfast.

Maintenance: has been given Doses up to 100 mg orally once a day or 60 mg orally twice a day. Patients continue to be treated for up to one year.

What is the dose of rabeprazole for children?

Dosage for Children with Gastroesophageal Reflux Disease

Age 12 years and over: 20 mg orally once a day, after breakfast. Therapy should be continued for 8 weeks.

Age 1 to 11 years:

Weight less than 15 kg: sprinkle 5 mg ready-to-drink capsule once a day with the option of increasing the dose to 10 mg orally once a day.

Weight 15 kg or more: Sprinkle 10 mg ready-to-drink capsules once a day

Duration: Up to 12 weeks

In what dosage is rabeprazole available?

Loose capsules, ready to drink, such as sodium: 5 mg, 10 mg

Tablets: 20 mg

Rabeprazole side effects

What side effects can be experienced due to rabeprazole?

Seek emergency medical help if you have any of the following signs of an allergic reaction: hives, difficulty breathing, swelling of the face, lips, tongue, or throat.

Stop using Rabeprazole and call your doctor right away if you have symptoms of magnesium deficiency such as:

• dizziness, confusion
• fast or uneven heart rate
• jerking muscle movements
• feeling restless
• diarrhea that is watery or bloody
• muscle cramps, muscle weakness or a feeling of weakness
• coughing or choking feeling
• convulsions (convulsions)

Less serious side effects may include:

• headache
• stomach pain, mild diarrhea
• insomnia or nervousness
• rash or itching

Not everyone experiences this side effect. There may be some side effects not listed above. If you have any concerns about side effects, please consult a doctor or pharmacist.

Rabeprazole Drug Warnings and Cautions

What should be known before using rabeprazole?

Before using certain drugs, consider the risks and benefits first. This is a decision you and your doctor will have to make. For this drug, pay attention to the following:

Allergy

Tell your doctor if you have any unusual or allergic reactions to this or any other medicine. Also tell your doctor if you have any other types of allergies such as to food, coloring, preservatives, or animal allergies. For over-the-counter products, read the labels on the packaging carefully.

Children

Appropriate studies have not been conducted to look at the relationship of age to the effects of Rabeprazole for treating GERD in children younger than 1 year of age. Safety and efficacy have yet to be determined

Appropriate studies have not been conducted to look at the relationship of age to the effects of Rabeprazole to treat other approved indications in the pediatric population. Safety and efficacy have not been confirmed.

Elderly

There have not been sufficient studies to date to pinpoint specific geriatric problems that will limit the usefulness of Rabeprazole in the elderly.

Is rabeprazole safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA).

The following references the pregnancy risk categories according to the FDA:

• A = No risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated,
• N = Unknown

Rabeprazole Drug Interactions

What medicines may interact with rabeprazole?

Using this medication with any of the following medicines is not recommended. Your doctor may decide not to treat you with this drug or replace some of the other medicines you take.

• Rilpivirine

Using this medication with any of the following medicines is not usually recommended, but may be necessary in some cases. If the two drugs are prescribed together, your doctor may change the dose or how often you use one or both drugs.

• Atazanavir
• Bosutinib
• Citalopram
• Clopidogrel
• Dabrafenib
• Dasatinib
• Erlotinib
• Eslicarbazepine Acetate
• Ketoconazole
• Ledipasvir
• Methotrexate
• Mycophenolate Mofetil
• Nelfinavir
• Nilotinib
• Pazopanib
• Saquinavir
• Topotecan
• Vismodegib

Using this medication with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If the two drugs are prescribed together, your doctor may change the dose or how often you use one or both drugs.

• Cranberry
• Digoxin
• Levothyroxine

Can food or alcohol interact with rabeprazole?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with rabeprazole?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

• diarrhea
• hypomagnesemia (low magnesium levels in the blood), history
• osteoporosis (bone problems)
• stomach infections (for example, pseudomembranous colitis) - use with caution. It might make things worse
• liver disease - use with caution. The effect may increase due to the slower neutralization of the drug in the body

Rabeprazole overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.