Sulindac: functions, dosage, side effects, how to use it

Functions & Usage

What is Sulindac used for?

Sulindac is a medicine to reduce pain, swelling and stiffness of joints due to arthritis. This drug is also used to treat arthritis of the spine, arthritis due to gout, shoulder tendonitis and shoulder bursitis (fluid in the sac in the shoulder joint that is inflamed). Sulindac belongs to a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). These drugs work by reducing inflammation and swelling.

How do you use Sulindac?

Follow the medication instructions given by your doctor or pharmacist before you start using this medicine. If you have questions, ask your doctor or pharmacist. Read the Medication Guide given by your pharmacist before you start using sulindac and each time you refill this medication. If you have questions, ask your doctor or pharmacist.

Take this medication as directed by your doctor, usually twice daily. Take this medication with a full glass of water (240 milliliters), unless your doctor directs you otherwise. Do not lie down for at least 10 minutes after taking this medicine. Take this medication either with food, right after eating, or with an antacid to prevent stomach upset.

Dosage is based on medical condition and response to treatment. To reduce the risk of side effects (such as stomach bleeding), use this medication at the lowest effective dose for the shortest possible time. Do not increase your dose or use it more often than prescribed. For chronic conditions such as arthritis, continue to use this medication as directed by your doctor. Discuss the risks and benefits with your doctor or pharmacist. Additionally, the manufacturer recommends that you should not take this drug for more than 400 milligrams per day as this can increase your risk of liver problems.

In certain conditions (such as rheumatoid), it may take 1-2 weeks before full benefits can be seen and if this medicine is taken regularly.

If you are taking this medication only under the conditions needed (not on a regular schedule), remember that pain relievers work best when used when the first signs of pain occur. If you wait until the pain has worsened significantly, the medication may not work very well.

Tell your doctor if your condition gets worse.

Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

How to store Sulindac?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Precautions & Warnings

What should be considered before using Sulindac drugs?

In deciding to use this drug, the risks of using the drug must be weighed against its benefits. This is up to you and your doctor. For this drug, the following should be considered:

Allergy

Tell your doctor if you have ever had an unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to food, coloring, preservatives, or animals. For non-prescription medicinal products, read labels or packaging about ingredients that make up the drug carefully.

Children

Appropriate studies have not been conducted on the relationship of age to the effects of sulindac in the pediatric population. Safety and efficacy are unknown.

Elderly

The precise studies carried out to date have not shown specific problems in the elderly that will limit the usefulness of sulindac in the elderly. However, elderly patients may be more sensitive to the effects of sulindac than younger adults and more likely to have age-related kidney problems, which may require an adjustment in the dose for patients receiving sulindac.

Is Sulindac safe for pregnant and lactating women?

There is no adequate research on the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA). (A = No risk, B = No risk in some studies, C = Possible risk, D = Positive evidence of risk, X = Contraindicated, N = Unknown)

Side effects

What are the possible side effects of Sulindac?

Get emergency medical help if you have signs of an allergic reaction such as: hives; hard to breath; swelling of the face, lips, tongue, or throat.

Stop using sulindac and call your doctor if you have serious side effects such as:

• Chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance

• Black, bloody, or tar-like stools, coughing up blood or vomit that looks like coffee grounds
• Urinating less than usual or not at all
• Nausea, stomach pain, fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
• Fever, sore throat, and severe headache, peeling skin, and red skin rash
• Bruising, severe tingling, numbness, pain, muscle weakness

Less serious side effects may include:

• Stomach pain, light heartburn or stomach pain, diarrhea, constipation; bloating, gas
• Dizziness, headache, nervousness
• Itchy skin or rash
• Dry mouth
• Increased sweating, runny nose
• Blurred vision
• Ringing in ears

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Drug Interactions

What drugs can interfere with the work of Sulindac drugs?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval

Using this medication with any of the following medicines is not recommended. Your doctor may decide not to treat you with this drug or change some of the other medicines you take.

• Ketorolac

Using this medication with any of the following medicines is not usually recommended, but may be necessary in some cases. If the two drugs are prescribed together, your doctor may change the dose or adjust how often you use one or both drugs.

• Abciximab
• Anagrelide
• Apixaban
• Ardeparin
• Argatroban
• Beta Glucan
• Bivalirudin
• Certoparin
• Cilostazol
• Citalopram
• Clopidogrel
• Clovoxamine
• Cyclosporine
• Dabigatran Etexilate
• Dalteparin
• Danaparoid
• Desirudin
• Dipyridamole
• Duloxetine
• Enoxaparin
• Eptifibatide
• Erlotinib
• Escitalopram
• Femoxetine
• Feverfew
• Flesinoxan
• Fluoxetine
• Fondaparinux
• Ginkgo
• Gossypol
• Sulindac
• Lepirudin
• Levomilnacipran
• Meadowsweet
• Methotrexate
• Milnacipran
• Nadroparin
• Nefazodone
• Parnaparin
• Paroxetine
• Pemetrexed
• Pentosan Polysulfate Sodium
• Pentoxifylline
• Pralatrexate
• Prasugrel
• Protein C
• Reviparin
• Rivaroxaban
• Sibutramine
• Tacrolimus
• Ticlopidine
• Tinzaparin
• Tirofiban
• Venlafaxine
• Vilazodone
• Vortioxetine
• Zimeldine

Using this medication with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If the two drugs are prescribed together, your doctor may change the dose or adjust how often you use one or both drugs.

• Acebutolol
• Acenocoumarol
• Acetohexamide
• Alacepril
• Alprenolol
• Amiloride
• Amlodipine
• Arotinolol
• Atenolol
• Azilsartan Medoxomil
• Azosemide
• Befunolol
• Bemetizide
• Benazepril
• Cyclopenthiazide
• Benzthiazide
• Bepridil
• Betaxolol
• Bevantolol
• Bisoprolol
• Bopindolol
• Bucindolol
• Bumetanide
• Bupranolol
• Buthiazide
• Candesartan Cilexetil
• Canrenoate
• Captopril
• Carteolol
• Carvedilol
• Celiprolol
• Chlorothiazide
• Chlorpropamide
• Chlorthalidone
• Cilazapril
• Clopamide
• Cyclopenthiazide
• Delapril
• Desvenlafaxine
• Dicumarol
• Dilevalol
• Diltiazem
• Enalaprilat
• Enalapril Maleate
• Eprosartan
• Esmolol
• Ethacrynic Acid
• Felodipine
• Flunarizine
• Fosinopril
• Furosemide
• Gallopamil
• Gliclazide
• Glimepiride
• Glipizide
• Gliquidone
• Glyburide
• Hydrochlorothiazide
• Hydroflumethiazide
• Imidapril
• Indapamide
• Irbesartan
• Isradipine
• Labetalol
• Lacidipine
• Landiolol
• Levobunolol
• Lidoflazine
• Lisinopril
• Lithium
• Losartan
• Manidipine
• Mepindolol
• Methyclothiazide
• Metipranolol
• Metolazone
• Metoprolol
• Moexipril
• Nadolol
• Nebivolol
• Nicardipine
• Nifedipine
• Nilvadipine
• Nimodipine
• Nipradilol
• Nisoldipine
• Nitrendipine
• Olmesartan Medoxomil
• Oxprenolol
• Penbutolol
• Pentopril
• Perindopril
• Pindolol
• Piretanide
• Polythiazide
• Pranidipine
• Propranolol
• Quinapril
• Ramipril
• Sotalol
• Spirapril
• Spironolactone
• Talinolol
• Tasosartan
• Telmisartan
• Temocapril
• Tertatolol
• Timolol
• Tolazamide
• Tolbutamide
• Torsemide
• Trandolapril
• Triamterene
• Trichlormethiazide
• Valsartan
• Verapamil
• Warfarin
• Xipamide
• Zofenopril

Can certain foods and drinks interfere with the work of Sulindac drugs?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interfere with the performance of Sulindac drugs?

The presence of other health problems in your body may affect the use of this medicine. Tell your doctor if you have other health problems, such as:

• Anemia
• Bleeding problems
• Blood clot
• Edema (fluid retention or body swelling)
• Heart attack, history
• Heart disease (for example, congestive heart failure)
• Hypertension (high blood pressure)
• Kidney disease (eg, kidney stones), history
• Liver disease (for example, hepatitis)
• Pancreatitis (inflammation of the pancreas)
• heartburn or intestinal bleeding, history
• Stroke, history - Use with caution. It might make things worse
• Aspirin related asthma sensitive
• Aspirin sensitivity, history - should not be used in patients with this condition
• Heart surgery (for example, coronary artery bypass graft) - Should not be used for pain relief right before or after surgery
• Systemic Lupus Erythematosus (SLE) - may cause side effects to get worse

Dose

The information provided is not a substitute for a doctor's prescription. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage for Sulindac for adults?

Usual Adult Dose for Acute Gout Arthritis:

200 mg taken twice daily with meals, continuing for 7-10 days.

The dose may be reduced or stopped after this time based on clinical response.

Usual Adult Dose for Ankylosing Spondylitis:

150-200 mg taken twice daily with meals.

The maximum daily dose should not exceed 400 mg.

Usual Adult Dose for Osteoarthritis:

150-200 mg taken twice daily with meals.

The maximum daily dose should not exceed 400 mg.

Usual Adult Dose for Pain:

150-200 mg orally twice a day with meals.

The maximum daily dose should not exceed 400 mg.

Usual Adult Dose for Rheumatoid Arthritis:

150-200 mg taken twice daily with meals.

The maximum daily dose should not exceed 400 mg.

Usual Adult Dose for Familial Adenomatous Polyposis:

Study - suppository formulations:

Initial: 150 mg via anus (rectum) twice daily for 3 months.

Maintenance: 67 mg via anus (rectum) daily, given in 2 divided doses.

What is the dosage of Sulindac for children?

The dosage has not been established in pediatric patients. This medicine may not be safe for your child. It is always important to understand the safety of drugs before using them. Please consult a doctor or pharmacist for more information.

In what dosages and preparations is Sulindac available?

Tablet, oral: 150mg, 200mg

What to do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (119) or immediately to the nearest hospital emergency department.

Overdose symptoms may include:

• lost consciousness
• passed out
• dizzy
• blurred vision
• stomach ache
• decreased frequency of urination

What should I do if I forget to take medicine or forget to take medicine?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical consultation, diagnosis or treatment.