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Definition

What is an anti-cyclic citrullinated peptide antibody?

Cyclic Citrullinated Peptide (CCP) is used in diagnosing arthritis. Citrullinated peptide antigen is formed in the conversion process of amino acid ornithine to Arginine. CCP antibodies appear in the early stages of rheumatoid arthritis (RA) and are present in the blood of most patients. If citrulline antibodies are found in the patient's blood, it can be concluded that the patient has RA. CCP antibodies can be used in diagnosing patients with arthritis of unknown cause, especially if traditional blood tests detect negative rheumatoid factor (RF) or below 50 units / mL.

When should I take anti-cyclic citrullinated peptide antibodies?

This test is run in conjunction with the rheumatoid factor (RF) test for patients with arthritis symptoms who have not been diagnosed or have been diagnosed with rheumatoid rheumatism. This test can also be used to see if you get negative results on rheumatoid factor (RF), which your doctor can suspect you have rheumatoid arthritis (RA).

Precautions & warnings

What should I know before taking anti-cyclic citrullinated peptide antibodies?

Many patients suffer from early-stage rheumatoid arthritis (RA) but do not experience an increase in rheumatoid factor (RF), making diagnosis at an early stage difficult. You can even be diagnosed with RF negative rheumatoid arthritis, if the number of CCP antibodies increases. The Anti-CCP test is important, because early diagnosis and treatment of rheumatoid arthritis (RA) can prevent joint damage. It is important that you understand the warnings above before running this test. If you have any questions, consult your doctor for further information and instructions.

Process

What should I do before taking anti-cyclic citrullinated peptide antibodies?

Your doctor will explain the test process to you. This test is a blood test. It is recommended that you wear clothes with short sleeves to help with the blood draw process.

How does the anti-cyclic citrullinated peptide antibody process?

The medical personnel in charge of drawing your blood will take the following steps:

wrap an elastic belt around your upper arm to stop blood flow. This makes the blood vessel under the bundle enlarge making it easier to insert the needle into the vessel
clean the area to be injected with alcohol
inject a needle into a vein. More than one needle may be required.
Insert the tube into the syringe to fill it with blood
untie the knot from your arm when enough blood is drawn
sticking gauze or cotton on the injection site, after the injection is complete
apply pressure to the area and then put a bandage on

What should I do after taking anti-cyclic citrullinated peptide antibody?

The doctor or nurse will take a sample of your blood. The pain depends on the skills of the nurse, the condition of the blood vessels and your sensitivity to pain. After the blood draw, it is recommended that you put a bandage on and apply light pressure to your vein to stop the bleeding. You can do your normal activities after the test.
If you have any questions about this test process, please consult with your doctor to understand more.

Explanation of the Test Results

What do my test results mean?

increased concentration
rheumatoid arthritis

The results of the anti-Cyclic Citrullinated Peptide Antibody test may vary depending on the laboratory. Consult with your doctor if you have questions regarding

test results.

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