Avandaryl: functions, dosage, side effects, how to use

Uses

What medicine is Avandaryl?

Avandaryl is an oral drug that contains a combination of rosiglitazone and glimepiride which is used to help control blood sugar in patients with type two diabetes. This medicine is not used to control blood sugar in patients with type one diabetes and diabetic ketoacidosis.

Rosiglitazone in Avandaryl works by increasing the body's sensitivity to insulin. Meanwhile, glimepiride is an oral diabetes drug that belongs to the sulfonylurea group. The glimepiride in Avandaryl works by increasing the production of insulin by the body.

The use of Avandaryl combined with a proper diet and exercise program will make your blood sugar control better. Avandaryl is not recommended for use with insulin. Taking Avandaryl together with insulin will increase your risk of developing serious heart problems.

How do you use Avandaryl?

Take Avandaryl as directed by your doctor. This medication is usually taken with the first large meal of the day, once daily. Swallow this drug whole, do not break, crush, or chew it.

At first, your doctor may give you a low dose first, then increase it gradually until you find the optimal dose for your blood sugar control.

The dosage given to you takes into account your health condition and your body's response to Avandaryl. Do not change or stop taking this drug without consulting your doctor.

Take this drug regularly to get the best benefits. To make it easier for you to remember, take this medication at the same time each day as the first meal of the day.

How to save Avandaryl?

Store this medication at room temperature away from direct light. Do not store this medication in a damp place, such as a bathroom. Make sure to seal the bottle tightly when not in use.

Do not flush or flush this medication down the toilet or drain unless instructed to do so. Discard this medication when it has expired or is no longer used. Talk to your pharmacist or local waste management company for solutions regarding the best way to dispose of this medication.

Dose

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage of Avandaryl for adult patients with type 2 diabetes?

Initial dose: rosiglitazone 4 mg / glimepiride 1 mg, once daily at the same time as the first meal of the day.

Initial dose for adults who have received treatment with a sulfonylurea or rosiglitazone: 4 mg / 2 mg

Maximum daily dose: rosiglitazone 8 mg / glimepiride 4 mg.

Patients who wish to switch from rosiglitazone to Avandaryl can increase it to no more than 2 mg after 1-2 weeks. Meanwhile, patients who switch from sulfonylurea to Avandaryl can increase it after 8-12 weeks. Wait 2-3 months to see the effects.

In what dosage and preparation is Avandaryl (rosoglitazone / glimepiride) available?

Tablet, Oral: 4 mg / 1 mg; 4 mg / 2 mg; 4 mg / 4 mg; 8 mg / 2 mg; 8 mg / 4 mg.

Side effects

What side effects might be caused by consuming Avandaryl?

Get emergency medical help right away if you experience an allergic reaction due to using Avandaryl which is characterized by itching, shortness of breath, swelling of the face, eyes, lips, tongue, or throat.

Call your doctor if you notice any of the following symptoms:

• Shortness of breath even when lying down, swelling, rapid weight gain
• Chest pain or heaviness, which radiates to the arms and even the jaw, nausea, sweating
• Pale skin, easy to bruise or bleed, limp
• Upper abdominal pain, itching, loss of appetite, concentrated urine, clay-colored stools, and yellowing of the eyes or skin. This could be a sign of pancreatitis
• Vision disorders
• Skin reactions, such as fever, sore throat, swelling of the face and tongue, a reddish rash on the skin that spreads (especially on the face and upper body) and causes skin to peel off
• The use of rosiglitazone can cause fluid retention, which is a condition in which the body retains water that comes out. This condition can worsen or cause heart failure. Patients should continue to be supervised when taking rosiglitazone. Reducing the dose or stopping consumption may be considered if these symptoms occur.

Some of the common side effects of Avandaryl:

• Headache
• Flu symptoms, such as stuffy nose, sneezing and sore throat

Not all side effects that occur are listed above. Consult with your doctor about any possible side effects that you are worried about will occur.

Warnings and Precautions

What should be known before taking Avandaryl?

• Inform your doctor about any drug allergies you have, including rosiglitazone and glimepiride, as well as all other medicines
• Tell your doctor your entire medical history before taking this medicine, including any previous or current illnesses, such as heart disease, history of heart attack or stroke, enzyme deficiency, kidney or liver disease, and pituitary gland disorders.
• Tell your doctor if you have vision problems caused by diabetes you have
• The use of this drug in women is more prone to causing fractures in the arms, thighs, or legs. Consult your doctor about this possibility
• Tell your doctor if you plan to become pregnant or are pregnant. Like other diabetes medicines, this drug causes hypoglycemia in babies born to mothers who are taking diabetes drugs near the time of birth
• Avandaryl use can also affect the menstrual cycle and increase the chance of an unplanned pregnancy. Call your doctor if you need birth control
• Use of this medicine may make you more prone to sunburn (sensitive to sunlight). Avoid exposure to direct sunlight in frequent intensity. Use sun cream or protective clothing when you are outdoors

Is Avandaryl safe for consumption for pregnant women?

Animal trials have shown that this drug poses a risk to an unborn fetus, although no trials have been carried out on humans. The United States Food and Drug Administration (FDA) classifies these drugs into category C (possibly risky).

Breastfeeding mothers are also not advised to give breast milk to their children when taking this drug because there are no studies whether this drug passes out of the body through breast milk.

Drug Interactions

What medicines may interact with Avandaryl?

Certain drugs will cause interactions when used together. This causes one of the drugs to not work optimally or increases the risk of serious drug side effects. Even so, sometimes your doctor may prescribe the two drugs at the same time if needed by making a dose adjustment.

Tell your doctor about any medications you are taking before taking Avandaryl, especially if you are taking:

• Insulin
• Heart drugs or blood pressure-regulating drugs
• Medicines to lower cholesterol

The list above does not include all types of drugs that interact with this drug. Keep a list of all the medications you take, including prescription and non-prescription drugs, vitamins, and herbal products.

Overdose

What should I do if I overdose on Avandaryl?

Seek emergency medical help immediately if you overdose on Avandaryl. Call 119 or go to the nearest hospital immediately. Avandaryl overdose can cause severe hypoglycemia which is life threatening.

Symptoms of extreme hypoglycemia include weakness, blurred vision, sweating, difficulty speaking, trembling, stomach pain, confusion, and seizures.

What should I do if I miss my scheduled medication?

Take the missed dose as soon as you remember. However, if it is too close to the next schedule, ignore the missed schedule and continue with the regular schedule. Do not double the dose at one time to make up for a missed dose.