Inviclot: functions, dosage, side effects, how to use it

Use

What is inviclot used for?

Inviclot is a brand of medicine in the form of an injection liquid. This drug contains the main active ingredient in the form of heparin, which is one of the anticoagulant drugs or blood thinners. This drug works by reducing the blood's ability to clot.

This drug also helps blood circulation by making natural substances in the body in the form of proteins that can prevent clots.

Inviclot is usually used to treat or prevent blood clots that occur due to certain health conditions or medical procedures. In addition, this drug is also used before surgery to reduce the risk of blood clots.

This medicine is included in prescription drugs, so you can only get it at a pharmacy with a prescription from a doctor.

How do I use inviclot?

There are several things you should pay attention to when using inviclot, including:

• Read the drug use guide every time you want to use this drug.
• If you have any questions, don't hesitate to ask your doctor or pharmacist.
• Usually, this medicine will be given by a medical professional, such as a doctor, the first time it is used.
• After that, you will be taught how to use this remedy independently at home.
• This drug is given by injection through a vein or directly through the skin, not through a muscle.
• The dose given to you is usually adjusted to your health condition and response to drug use.
• Only provide the injecting device when you are ready to do so.
• Do not use the medicine if there are small particles in the liquid, or when the liquid has changed color.
• While using this medicine you will need to have frequent blood tests.
• The timing of the examination must be right so that the doctor can help determine whether you can continue to use this medicine or not.
• Use the syringe and injection fluid bottle only once at a time.
• Make sure you are using the correct dosage, as wrong doses can lead to fatal conditions.

How do I save inviclot?

If you are able to use this medicine independently at home, then you must store the liquid of this medicine properly so that the drug does not spoil easily. Things that you should pay attention to include:

• This drug is best stored at room temperature.
• Keep this medication away from exposure to sunlight and direct light.
• Also keep this drug away from damp places.
• Do not store this medication in the bathroom.
• Do not also store and freeze this drug in the freezer.
• Keep this medication out of reach of children and pets.

Meanwhile, if this drug can no longer be used, it has expired, or you have indeed stopped using this drug, you must dispose of it in a good waste disposal procedure.

Do not combine medicinal waste with other household waste. In addition, do not dispose of the medicine by flushing it in the toilet or other sewer because it can pollute the environment.

If you are not sure how to properly dispose of a medicine, ask your pharmacist or a local waste disposal agency and get more information.

Dose

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the adult dosage for inviclot?

Adult dosage for deep vein thrombosis (DVT)

Using a follow-up infusion

• Initial dose: 5000 International Units (IU) injected intravenously.
• Maintenance dose: 20000-40000 IU once every 24 hours given by continuous intravenous infusion.

Using a temporary infusion

• Initial dose: 10000 IU injected intravenously
• Maintenance dose: 5000-10000 IU injected intravenously every 4-6 hours.

Using subcutaneous injection

• 333 IU / kilogram (kg) body weight followed by 250 IU / kg body weight every 12 hours.

Adult dose for prevention of thromboembolism in atrial fibrillation

Using a follow-up infusion

• Initial dose: 5000 IU by IV injection
• Maintenance dose: 20000-40000 IU every 24 hours

Using a temporary infusion

• Initial dose: 10000 IU by IV injection
• Maintenance dose: 5000-10000 IU by IV injection, given every 4-6 hours.

Using subcutaneous injection

• 333 IU / kilogram (kg) body weight followed by 250 IU / kg body weight every 12 hours.

Adult dose for pulmonary embolism (blockage of one of the pulmonary arteries)

Using a follow-up infusion

• Initial dose: 5000 IU by IV injection
• Maintenance dose: 20000-40000 IU every 24 hours

Using a temporary infusion

• Initial dose: 10000 IU by IV injection
• Maintenance dose: 5000-10000 IU by IV injection, given every 4-6 hours.

Using subcutaneous injection

• 333 IU / kilogram (kg) body weight followed by 250 IU / kg body weight every 12 hours.

Adult dosage for thrombotic disorders

Using a follow-up infusion

• Initial dose: 5000 IU by IV injection
• Maintenance dose: 20000-40000 IU every 24 hours

Using a temporary infusion

• Initial dose: 10000 IU by IV injection
• Maintenance dose: 5000-10000 IU via IV injection that is given every 4-6 hours.

Using subcutaneous injection

• 333 IU / kilogram (kg) body weight followed by 250 IU / kg body weight every 12 hours.

Adult dose for blood clots in small blood vessels (disseminated intravascular coagulation)

Using a follow-up infusion

• Initial dose: 5000 IU by IV injection
• Maintenance dose: 20000-40000 IU every 24 hours

Using a temporary infusion

• Initial dose: 10000 IU by IV injection
• Maintenance dose: 5000-10000 IU via IV injection that is given every 4-6 hours.

Using subcutaneous injection

• 333 IU / kilogram (kg) body weight followed by 250 IU / kg body weight every 12 hours.

Adult dosage for arterial thrombosis

Using a follow-up infusion

• Initial dose: 5000 IU by IV injection
• Maintenance dose: 20000-40000 IU every 24 hours

Using a temporary infusion

• Initial dose: 10000 IU by IV injection
• Maintenance dose: 5000-10000 IU via IV injection that is given every 4-6 hours.

Using subcutaneous injection

• 333 IU / kilogram (kg) body weight followed by 250 IU / kg body weight every 12 hours.

Adult dosage for thoracoplastic surgery

• Initial dose: at least 150 IU / kilogram (kg)
• Time of procedure: 300 IU / kg used for 60 minutes
• 400 IU / kg is used for those that need more than 60 minutes

Adult dosage for vascular surgery

• Initial dose: at least 150 IU / kilogram (kg)
• Time of procedure: 300 IU / kg used for 60 minutes
• 400 IU / kg is used for those that need more than 60 minutes

What is the child's dosage for inviclot?

Children's dosage for thrombotic disorders

• Treatment dose: 50-100 IU / kilogram (kg) via IV bolus
• Preventive dose: 10-15 IU / kg / hour via continued infusion
• Dosage for patients at risk of congenital heart disease: 10-15 IU / kg / hr via a follow-up infusion.

In what dosage is Inviclot available?

Inviclot is available as an injection liquid: 5000 IU / mL

Side effects

What side effects may occur due to using Inviclot?

As with other side effects of use, inviclot can also cause symptoms of side effects. These symptoms can range from mild to serious health conditions.

Mild side effects that may arise are:

• Allergic reaction in the area where this medicine is injected. Usually in the form of redness, pain, bruising, or soreness.
• Hair loss

The side effects mentioned above will disappear over time. However, if the condition gets worse or doesn't get better soon, tell your doctor.

In addition, there are other serious side effects that may arise as a result of using this drug, including:

• Bleeding or bruising of unknown cause
• Vomiting blood
• The stool contains blood or is dark in color
• Dark urine
• Very, very tired feeling, but it is not known what causes it
• Nausea and vomiting
• The chest hurts as if it is pressed
• Coughing up blood
• Excessive sweating
• Headaches that appear suddenly
• The head felt light as if it was about to pass out
• The body suddenly loses balance
• Suddenly it couldn't go well
• Impaired eyesight
• The skin turns purple or dark
• Fever to chills
• Gasping for breath
• Hoarseness
• Difficulty breathing and swallowing
• Osteoporosis (for long-term use)

If you experience serious side effects, contact your doctor immediately and get medical care right away.

Not all possible side effects are listed in this list. If you experience other side effects from using Inviclot, ask your doctor how to deal with them.

Warnings & Precautions

What should I know before using inviclot?

Before you decide to use inviclot, there are a few things you should know, including:

• Do not use inviclot if you have it against this drug or its main active ingredient, heparin.
• While using this medication, avoid activities that can increase your risk of getting injured. The reason is, if you are injured, you may experience bleeding.
• This medicine also contains sodium in it. If you are on a sodium diet, ask your doctor if this medication is safe for you to use.
• Women who are 60 years of age and over may be more sensitive to the side effects that may occur from using this drug. One of them is bleeding.
• Do not use this medication if you have an allergy to products containing pork.
• Do not use this medication if you have experienced a decrease in the number of platelets due to previous use of drugs containing heparin.
• Do not use this medication if you experience frequent, uncontrolled bleeding.
• Ask your doctor if this drug is safe for you to use, especially if you have experienced conditions such as high blood pressure, blood clotting disorders, intestinal problems, liver problems, and bacterial endocarditis.

Is inviclot safe to use for pregnant and lactating women?

It is not certain whether this drug is safe for use by pregnant and lactating women. However, this drug is included in pregnancy risk category C according to the Food and Drug Administration (FDA) or equivalent to the Food and Drug Supervisory Agency (BPOM) in Indonesia. The following references the pregnancy risk categories according to the FDA:

• A = No risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated,
• N = Unknown

Likewise with pregnant women. It is still unknown whether this drug can pass through breast milk (ASI) and be consumed by a nursing infant. If you are taking this medication, make sure you are aware of the potential benefits and risks of using the drug for you and your baby.

Interaction

What medicines can interact with Inviclot?

Drug interactions may occur if used at the same time. If this happens, drug interactions can be good or bad, depending on what drug the inviclot interacts with. The good effect that may occur is that the interaction becomes one of the best types of treatment for your condition.

However, interactions can also cause adverse effects where the way the drug works may change or the risk of side effects may increase. Therefore, record all types of drugs you use, from prescription drugs, non-prescription drugs, to multivitamins and dietary supplements. Then, give it to the doctor so that you can help determine the appropriate dose for your condition.

The following are some of the types of drugs that may interact with Inviclot, including:

• Advil (ibuprofen)
• aspirin
• Coumadin (albuterol / ipratropium)
• ibuprofen
• Lovenox (enoxaparin)
• Plavix (clopidogrel)
• Vitamin B12 (cyanocobalamin)
• Vitamin D3 (cholecalciferol)
• Vitamin K (phytonadione)
• warfarin
• Zofran (ondansetron)

What foods and alcohol can interact with Inviclot?

Certain medications should not be consumed at mealtimes or when eating certain types of food because interactions may occur. Consuming alcohol or tobacco-derived products with certain drugs can also cause interactions. Discuss with your health care professional the use of drugs with food, alcohol, or products derived from tobacco.

What health conditions can interact with Inviclot?

There are several health conditions that can interact with inviclot. The interactions that occur may increase the risk of side effects or make your health condition worse. Tell your doctor if you have certain conditions, and make sure whether you are safe using this medicine or not. These conditions include:

• Active bleeding
• Hypertension or high blood pressure
• Premature
• A malfunctioning kidney
• Hyperkalemia, or calcium levels that are too high
• Thrombocytopenia, a lack of platelet or platelet levels in the body

Overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you miss a dose by mistake, ask your doctor what you should do about it. Do not double the dose, because doses that are not according to the rules may increase the risk of overdose.

In order not to forget to use a dose of medicine, use the medicine at the same time every day. It also helps you get the most of it.

Hello Health Group does not provide medical advice, diagnosis or treatment.