Iron polymaltose complex: functions, dosage, side effects, how to use

What Drug Iron Polymaltose Complex?

What is the iron polymaltose complex for?

Iron polymaltose complex is a drug to treat iron deficiency anemia that occurs in the following situations:

• Have contraindications from other oral anemia medications
• When the enteric absorption of iron is impaired
• When patients with gastrointestinal intolerance still render oral therapy useless.

This drug is commonly sold under the trademark Maltofer.

This medicine may be given to you for other reasons. Talk to your doctor about more information.

How to use the iron polymaltose complex?

It is important to know how to inject the correct medicine. This medicine should not be injected into the arm or any other open area. The wrong way of injecting it can result in constant pain and discoloration of the skin.

Iron polymaltose complex injection should be prescribed by medical personnel in MR / 645 intravenous preparation. The infusion is ordered in the form of iron content, not iron polymaltose. The iron polymaltose complex is only compatible with 0.9% sodium chloride, and should not be mixed with other drugs or solutions.

The calculated dose that must be given is added up to 500 ml of 0.9% sodium chloride. (NB: In fluid-restricted patients it may be necessary to give the total dose in divided doses with the same concentration in smaller volumes).

Add the required dose of iron polymaltose through a 5 micron filter, available at pharmacies (or stores). Iron should not be injected into the IV set tube. Up to 2,500mg elemental iron can be added to 500 ml of 0.9% sodium chloride.

The oral version of this medicine works better if you take it on an empty stomach. You can take the iron complex with food if the medicine is prone to causing stomach upset. However, some foods such as eggs, whole wheat bread, cereals, dairy products, coffee, and tea may make this medicine not work properly.

Talk to your doctor further about the best way to take the iron polymaltose complex with food.

How to store the iron polymaltose complex?

This medication is best stored at room temperature. Keep away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it.

Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so.

Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Rules of Use for Iron Polymaltose Complex

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the iron polymaltose dosage for adults?

Oral

Iron deficiency anemia

Adult: Chewable tablet / syrup / drop form: Dose equivalent to 100 mg of elemental iron daily, up to 300 mg per day.

Intramuscular

Iron deficiency anemia

Adults: Injection containing 100 mg Iron Polymaltose / 2 ml

Management by ventro-gluteal injection according to the Hochstetter method (see package details).

Total dose of iron required (mg): Wt (kg) x (normal hemoglobin-true hemoglobin in g / L) x 0.24 + iron depot. Iron depot is calculated as 15 mg / kg up to 34 kg, max 500 mg for body weight ≥34 kg.

Give an alternate injection dose of 2 ml (or 4 ml at longer intervals) until the total dose is reached. Maximum single dose:> 10-45 kg: 2 ml; > 45 kg: 4 ml.

Intravenous

Iron deficiency anemia

Adult: In the form of injection containing 100 mg Iron Polymaltose iron / 2 ml.

Total dose of iron required (mg): Wt (kg) x (normal hemoglobin-true hemoglobin in g / L) x 0.24 + iron depot. Iron depot is calculated as 15 mg / kg up to 34 kg, max 500 mg for body weight ≥34 kg.

See the product packaging section. The first 50 ml is infused slowly (5-10 drops / minute) and observe the patient carefully. If the patient's body is well tolerated, increase to 30 drops / min (based on 0.067ml drop volume).

What is the dose of iron polymaltose for children?

Intramuscular

Iron deficiency anemia

Child: In the form of an injection containing 100 mg iron Polymaltose iron / 2 ml: Manage by ventro-gluteal injection according to the Hochstetter method (see product packaging details) total required dose of iron (mg): Wt (kg) x (normal hemoglobin-hemoglobin which is actually in g / L) x 0.24 + iron depot.

Iron depot is calculated as 15 mg / kg up to 34 kg, a maximum of 500 mg for body weight ≥34 kg. Maximum single dose:> 10-45 kg: 2 ml; 5-10 kg: 1 ml; infant (up to 5 kg): 0.5 ml.

Intravenous

Iron deficiency anemia

Child: In the form of an injection containing 100 mg of iron. Iron Polymaltose / 2 ml: Total dose of iron required (mg): Wt (kg) x (normal hemoglobin-actual hemoglobin in g / L) x 0.24 + iron depot. Iron depot is calculated as 15 mg / kg up to 34 kg, max 500 mg for body weight ≥34 kg.

See the product packaging section. The first 50 ml to infuse slowly (5-10 drops / minute) and observe the patient carefully. If the patient's body is well tolerated, increase to 30 drops / min (based on 0.067ml drop volume).

In what dosage is the iron polymaltose complex available?

Iron polymaltose complex is a drug that is available in the form of an oral (oral medicine) or injection (injection drug).

The preparation and dosage of the iron polymaltose complex are:

• Solution (intramuscular): 100 mg / 2 ml
• Chewable tablets / syrup / drops (oral)

Iron Polymaltose Complex dosage

What side effects can be experienced due to the iron polymaltose complex?

Parenteral side effects are rare. However, the following reactions are known to occur after parenteral iron therapy.

Common side effects of the iron polymaltose complex are:

• Heat, sweating, chills and fever
• Chest and back pain

After intramuscular injection:

• Pain in the injection site
• Local inflammation with inguinal lymphadenopathy
• Lower abdominal pain

Hypersensitivity:

• Anaphylaxis

Gastrointestinal:

• Nausea and vomiting

Central nerve system:

• Headache
• Dizzy

Musculoskeletal:

• Joint and muscle pain
• Arthralgia
• Stiff sensation in the arms, legs or face

Cardiovascular:

• Fainting
• Tachycardia
• Hypotension
• Circulatory collapse

Respiration:

• Bronchospasm with dyspnoea

Hematological:

• Generalized lymphadenopathy

Dermatologist:

• Rash
• urticaria
• angioneurotic edema

The possibility of a new reaction will appear 1-2 days after injection of the drug. Not everyone experiences this side effect. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Iron Polymaltose Complex side effects

What should be known before using the iron polymaltose complex?

Before using this medication, tell your doctor if you:

• Hypersensitivity to iron (III) hydroxide polymaltose complex
• Have anemia not caused by simple iron deficiency (eg hemolytic anemia, megablastic anemia caused by vitamin B12 deficiency, erythropoiesis disorders, marrow hypoplasia)
• Excess iron (eg Hemochromatosis, Hemosiderosis)
• Has Osler-Rendu-Weber syndrome
• Have chronic polyarthritis
• Have bronchial asthma
• Have an acute kidney infection
• Have uncontrolled hyperparathyroidism
• Have decompensated liver cirrhosis
• Have infectious hepatitis
• Currently undergoing the first trimester of pregnancy

This medication may affect certain laboratory tests. Tell your healthcare provider and laboratory technician that you are taking an iron complex (iron / folic acid / vitamin C / vitamin B12) preparation.

Is Iron polymaltose complex safe for pregnant and lactating women?

There is not sufficient research to determine the risks of using the medication in women during pregnancy or breastfeeding. Always consult your doctor to weigh the potential benefits and risks before using this medication.

Iron polymaltose complex is a drug that belongs to it pregnancy risk category D according to the Foods and Drugs Association (FDA) in the United States.

• A = no risk
• B = no risk in several studies
• C = there may be a risk
• D = tested positive for risk
• X = contraindicated
• N = unknown

Iron Polymaltose Complex Drug Warnings and Cautions

What medicines may interact with iron polymaltose complex?

Drug interactions can change the performance of the drug or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

As with all parenteral iron preparations, ampoules should not be given at the same time as oral iron because oral iron absorption is reduced. Oral iron therapy should not be used until at least one week after the last iron injection.

Concurrent management with Angiotensin Converting Enzyme Inhibitor (ACE) will increase the adverse effects associated with parenteral iron preparations, eg erythema, stomach cramps, nausea, vomiting and hypotension.

Can food or alcohol interact with the iron polymaltose complex?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions may interact with iron polymaltose complex?

Your health condition can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

• bronchial asthma
• low ability to bind iron
• lack of folic acid
• a history of allergies
• hepatic insufficiency
• cardiovascular disease
• arthritis

Drug Interactions of Iron Polymaltose Complex

What should I do in an emergency or overdose?

Accidental overdose of drugs containing iron complex (iron / folic acid / vitamin C / vitamin B12) is the leading cause of death in children under 6 years due to poisoning.

In case of an emergency or overdose, contact the local emergency services provider (118) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.