Moxifloxacin: functions, dosage, side effects, how to use it

What drug Moxifloxacin?

What is Moxifloxacin for?

Moxifloxacin is a drug used to treat various bacterial infections. This drug belongs to a class of drugs called quinolone antibiotics. It works by stopping bacterial growth.

This antibiotic treats only bacterial infections. This antibiotic will not work for viral infections (such as colds, flu). Unnecessary or excessive use of antibiotics can cause their effectiveness to decrease.

How to use Moxifloxacin?

Take this medication with or without food as directed by your doctor, usually once daily. The dosage and length of treatment are based on your medical condition and response to treatment. Drink plenty of fluids while using this medicine unless your doctor tells you otherwise.

Take this drug at least 4 hours before or 8 hours after using other drugs that may bind to the drug moxifloxacin and cause decreased effectiveness. Ask your pharmacist about other medicinal products you use. Some examples of these other drugs include: quinapril, sucralfate, vitamins / minerals (including iron and zinc supplements), and products containing magnesium, aluminum, or calcium (such as antacids, ddI solutions, calcium supplements).

Antibiotics work best when the amount of medicine in your body is at a constant level. Therefore, use this drug regularly.

Continue to use this medication until the prescribed amount is finished, even if symptoms have disappeared after a few days. Stopping treatment too early can result in the infection returning.

tell your doctor if your condition does not improve or gets worse.

Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

How to store Moxifloxacin?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Moxifloxacin dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage of Moxifloxacin for adults?

Usual Adult Dose for Bronchitis

Chronic acute bacterial bronchitis infection: 400 mg orally or IV every 24 hours for 5 days.

Usual Adult Dose for Intraabdominal Infection

Complications: 400 mg orally or IV every 24 hours for 5 to 14 days.

Usual Adult Dose for Pneumonia

Group-pneumonia infection: 400 mg orally or IV every 24 hours for 7 to 14 days.

Usual Adult Dose for Sinusitis

Acute bacterial sinusitis: 400 mg orally or IV every 24 hours for 10 days.

Usual Adult Dose for Skin Infections or Soft Tissue Infections

400 mg orally or IV every 24 hours. Duration: 7 to 21 days for complicated infections 7 days for uncomplicated infections.

Usual Adult Dose for Skin and Structural Infections

400 mg orally or IV every 24 hours. Duration: 7 to 21 days for complicated infections 7 days for uncomplicated infections.

Usual Adult Dose for Bacillus Anthracis Inhalation

Treatment of mass casualties or prevention of inhalation. Anthrax: 400 mg orally once daily for 60 days.

Usual adult dose for anthrax prophylaxis: treatment of mass victims or prevention of inhalation. Anthrax: 400 mg orally once a day for 60 days.

Usual Adult Dose for Active Tuberculosis

400 mg orally or IV once a day.

What is the dosage of Moxifloxacin for children?

The dosage for children has not been determined. Consult your doctor for more information.

In what dosage is Moxifloxacin available?

• Tablet, Oral: 400 mg
• Injectable, parenteral: 400 mg in 0.8% sodium chloride

Moxifloxacin side effects

What side effects can be experienced due to Moxifloxacin?

SIDE EFFECTS: Blurred vision, watery eyes, eye pain / dryness / redness / itching may occur. If any of these effects do not improve or get worse, inform your doctor.

Remember that your doctor has prescribed this medication because he or she has judged that the benefits to you outweigh the risk of side effects. Many people using this drug do not experience serious side effects.

Tell your doctor right away if you develop eye swelling, one of the possible side effects.

Allergic reactions to this drug do not usually occur, but seek medical help immediately if one occurs. Symptoms of an allergic reaction include: rash, itching / swelling (especially face / tongue / throat), dizziness, difficulty breathing.

Not everyone experiences this side effect. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Moxifloxacin Drug Warnings and Cautions

What should be known before using Moxifloxacin?

Before using moxifloxacin,

• tell your doctor and pharmacist if you are allergic to or have a severe reaction to moxifloxacin, other quinolones or fluoroquinolone antibiotics such as ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available in the US), gemifloxacin (factive), levofloxacin (Levaquin), lomefloxacin (Maxaquin)) (not available in the US), nalidixic acid (NegGram), norfloxacin (Noroxin), ofloxacin (Floxin), and Sparfloxacin (Zagam) (not available in the US), or other drugs
• tell your doctor and pharmacist about the prescription and nonprescription drugs, vitamins, nutritional supplements, and herbal products you are using or will be using. Be sure to mention the following: other anticoagulants such as anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven) certain antidepressants antipsychotics (drugs to treat mental illness) nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Naprosyn, others) cisapride (Propulsid) (not available in the US) diuretic ('water pill') erythromycin (EES, E-Mycin, Erythrocin, and others) or certain medications for irregular heartbeats including amiodarone (Cordarone), Disopyramide (Norpace), procainamide (Procanbid), quinidine, and sotalol (Betapace, Betapace AF, Sorine). Your doctor may need to change the dose of your medication or monitor you carefully for side effects
• use moxifloxacin at least 4 hours before or at least 8 hours after you take this medicine: antacids containing magnesium or aluminum (Maalox, Mylanta, Tums, others) ddI (Videx) sucralfate (Carafate) or vitamin supplements containing iron or zinc
• tell your doctor if you or someone in your family have or have had a prolonged QT interval (a rare heart problem that can cause an irregular heartbeat, blackout, or sudden death) or an irregular heartbeat, and if you have or have ever had nerve problems, cerebral arteriosclerosis (narrowing of blood vessels in or near the brain that can cause a stroke or mini-stroke), seizures, chest pain, slow heartbeat, potassium levels, low blood pressure, or liver disease
• tell your doctor if you are pregnant or planning to become pregnant or if you are breastfeeding. If you become pregnant while using moxifloxacin, call your doctor
• You should know that moxifloxacin can cause dizziness and lightheadedness. Do not drive a car, operate machinery, or participate in activities that require alertness or coordination until you know how moxifloxacin affects you.
• Avoid unnecessary or prolonged sun exposure or exposure to ultraviolet light (tanning beds and sunlamps) and wear protective clothing, sunglasses, and sunscreen. Moxifloxacin can make your skin sensitive to sunlight. Call your doctor if you experience skin redness or blisters during treatment with moxifloxacin.

Is Moxifloxacin safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA).

The following references the pregnancy risk categories according to the FDA:

• A = No risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated,
• N = Unknown

There are not sufficient studies in women to find out the risk to the baby when the mother takes this drug during breastfeeding. Consider the potential benefits and potential risks before taking this medication during breastfeeding.

Moxifloxacin Drug Interactions

What medicines may interact with Moxifloxacin?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval

Tell your doctor about all other medicines you use, especially:

• erythromycin
• diuretics or "water pills"
• insulin or oral diabetes medication
• a blood thinner - warfarin, Coumadin, Jantoven
• heart rhythm drugs - amiodarone, disopyramide, dofetilide, dronedarone, procainamide, quinidine, sotalol, and others
• medicine to treat depression or mental illness - amitriptylline, clomipramine, desipramine, iloperidone, imipramine, nortriptyline, and others
• NSAIDs (non-steroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, etc. or
• steroid drugs - prednisone, dexamethasone, methylprednisolone, and others

Can food or alcohol interact with Moxifloxacin?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions may interact with Moxifloxacin?

The presence of other health problems in your body may affect the use of this drug. tell your doctor if you have other health problems, such as:

• bradycardia (slow heart rate) or
• diabetes
• diarrhea
• heart disease
• heart rhythm problems (eg, long QT interval), or a family history
• hypoglycemia (low blood sugar)
• hypokalemia (low potassium in the blood)
• seizures (epilepsy), or a history. Use with care. It might make things worse.
• brain disease (for example, hardening of the arteries)
• Kidney illness
• liver disease (including cirrhosis)
• organ transplant (for example, heart, kidney, or lung), including history
• tendon disorders (eg, rheumatoid arthritis), history. Use with care. May cause side effects to be worse
• myasthenia gravis (severe muscle weakness), or the presence of-Should not be used in patients with this condition

Moxifloxacin overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.