Brufen: functions, dosage, side effects, how to use it

Use

What is the function of Brufen?

Brufen is a drug used to treat minor aches and pains caused by flu symptoms, headaches, toothaches, back pain or muscle pain, menstrual pain, or arthritis. Can also be used to reduce fever.

How do you use Brufen?

Use Brufen as recommended by your doctor. Check the label on the medicine for dosing instructions.

• Brufen is available with medically instructed information. Read it carefully.
• Take by mouth with or without food. Can be consumed with food if it upsets your stomach. Consumption with food will not lower the risk of stomach or digestive problems. Consult your doctor or pharmacist if you have stomach pain problems.
• Take Brufen with a full glass of water (8 oz / 240 ml) as directed by your doctor.

How to save Brufen?

Do not store above 25 ° C. Keep in the original packaging.

Warning

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What should I pay attention to before using Brufen?

Brufen should not be used in patients with hypersensitivity to active substances or to excipients.

Brufen should not be used in patients who have hypersensitivity reactions (asthma, urticarials, angioedema or rhinitis) after taking ibuprofen, aspirin, or other NSAIDs.

Brufen is also contraindicated in patients who have a history of gastrointestinal bleeding or perforation, regarding NSAID therapy. Brufen should not be used in patients who have had or still have gastric ulcers or gastrointestinal bleeding.

Brufen should not be used in patients with conditions that are prone to bleeding.

Brufen should not be used in patients with severe heart failure (NYHA class IV), hepatic failure, and kidney failure.

Brufen should not be used during the last trimester of pregnancy.

• Brufen can increase your risk of fatal heart attack or stroke, especially if you use it for a long time or at high doses, or if you have heart disease. Even people without heart disease or risk factors can have a stroke or heart disease if they take this medicine.
• Do not use Brufen before or after bypass surgery (coronary artery bypass graft, or CABG).
• Brufen can cause stomach or intestinal bleeding, which can be fatal. This condition can appear without warning when you use Brufen, especially in adults.
• You should not use Brufen if you are allergic to Brufen, or if you have had an asthma attack or a severe allergic reaction after taking aspirin or an NSAID.

Is Brufen safe for pregnant and lactating women?

During the first and second trimesters, Brufen should not be given unless absolutely necessary. If Brufen is used in women who are trying to become pregnant, or during the first or second trimester, the dose should be given very low and of short duration.

During the third trimester of pregnancy, all prostaglandin synthesis inhibitors can expose the fetus to the following risks:

• Cardiopulmonary poisoning (premature ductus arteriosus and pulmonary hypertension)
• Renal dysfunction, which can lead to kidney failure with oligohydramnios.

Late in pregnancy, prostaglandin synthesis inhibitors can expose mother and baby to:

• Prolonged bleeding time
• Obstruction of uterine contractions, which can result in delay or prolongation of the birth process.

Brufen should not be used in pregnant women in the third trimester.

In limited studies so far, Brufen can be absorbed in breast milk even at low concentrations. Therefore, all NSAIDs including Brufen should be avoided while breastfeeding.

Side effects

What are the possible side effects of Brufen?

• The most common side effects: constipation; diarrhea; dizzy; gas; headache; stomach heat; nausea; stomach ache.
• Severe side effects: severe allergic reaction (rash; itching; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; bloody or black, loose stools; changes in urine production; chest pain; confusion; dark urine; depression; fainting; fast or irregular heartbeat; fever, chills, or sore throat; mood or mental changes; numbness of the arms or legs; one-sided weakness; redness, swelling, blistering, peeling skin or; ringing in the ears; seizures severe headache or dizziness; severe or persistent stomach pain or nausea, vomiting; severe; shortness of breath; neck stiffness; sudden weight gain; swelling of the hands, feet, or legs; unusual bruising or bleeding; no muscle pain. usual; unusual tiredness or weakness; vision or speech changes; vomiting that looks like coffee grounds; yellowing of the skin or eyes.

Drug Interactions

What medicines should not be taken at the same time as Brufen?

Caution should be paid to patients who are also taking any of the following drugs:

• Antihypertensives, beta-blockers and diuretics
• Cardiac glycosides
• Cholestyramine
• Lithium: reduces lithium elimination.
• Methotrexate: NSAIDs can inhibit tubular secretion of methotrexate and reduce methotrexate clearance.
• Cyclosporin: Increases the risk of nephrotoxicity.
• Mifepristone
• Analgesics and other cyclooxygenase-2, selective inhibitors
• Aspirin (Acetylsalicylic acid) and low doses of Aspirin
• Corticosteroids
• Anticoagulants
• Quinolone antibiotics
• Sulfonylureas
• Anti-platelet agents and selective serotonin reuptake inhibitors (SSRI)
• Tacrolimus
• Zidovudine
• Aminoglycosides
• Herbs: Ginkgo biloba can potentially be a bleeding risk with NSAIDs.
• CYP2C9 inhibitors: ibuprofen dose reductions should be considered when potency CYP2C9 inhibitors are registered concurrently, half when high-dose ibuprofen is registered with voriconazole or fluconazole.

Are there foods and drinks that should not be consumed when using Brufen?

Ask your doctor before using ibuprofen together with ethanol. Do not drink alcohol while taking ibuprofen. Alcohol can increase the risk of stomach bleeding caused by ibuprofen. Call your doctor when you have symptoms of bleeding in the stomach or intestines. These include black, bloody, soft stools, or coughing up blood that looks like coffee grounds. It is very important to tell your doctor about all medications you are taking, including vitamins and herbs. Don't stop using any medication without talking to your doctor first.

Fluid retention and edema have been reported in association with the use of nonsteroidal anti-inflammatory drugs. Therapy with this drug should be managed with caution in patients who have previously had fluid retention, hypertension, or a history of heart failure. Continuously monitored blood pressure and cardiovascular status during use of this medicine.

Dose

The following information cannot be used as a substitute for a doctor's prescription. You MUST consult your doctor or pharmacist before using Brufen.

What is the dose of Brufen for adults?

The recommended dose is 1200-1800 mg per day divided into different doses. Some patients can take 600-1200 mg per day. In acute conditions, increase the dose until the symptoms are controlled, the total daily dose should not exceed 2400 mg divided into different doses.

What is the dose of Brufen for children?

• Children over 12 years of age: The recommended dose is 1200-1800 mg per day divided into different doses. Some patients can take 600-1200 mg per day. In acute conditions, increase the dose until the symptoms are controlled, the total daily dose should not exceed 2400 mg divided into different doses.
• Children under 12 years: The daily dose of Brufen is 20 mg / kg of body weight in different doses.
• For juvenile rheumatoid arthritis, up to 40 mg / kg body weight in divided doses
• Not recommended for children weighing less than 7 kg.

In what form is Brufen available?

Brufen is available in the following dosages and strengths:

• Brufen 400 mg tablet
• Brufen 200 mg tablet

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (119) or immediately to the nearest hospital emergency department.

Signs and symptoms of poisoning in general have not been observed at doses below 100 mg / kg in children or adults. However, children have seen symptoms of poisoning after ingesting 400 mg / kg or more.

What should I do if I forget to take / take medicine?

If you forget a dose of Brufen, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.