Cefoperazone: functions, dosage, side effects, how to use it

Cefoperazone What Medicine?

What is cefoperazone for?

Cefoperazone is an antibiotic used to treat a wide variety of bacterial infections. This drug belongs to the cephalosporin class of antibiotics. The way cefoperazone antibiotics work is to stop bacterial growth.

Some types of bacterial infections that can be treated with cefoperazone are as follows:

• respiratory tract infections (eg bacteria S. pneumoniae , H. influenzae, S. aureus)
• peritonitis
• septicemia
• skin infection
• pelvic inflammatory disease, endometritis, and other genital infections
• urinary tract infections (eg bacteria E. coli and P. aeruginosa)

Cefoperazone is an antibiotic that will not work for viral infections such as colds and flu. Using antibiotics when they are not needed can increase your risk of getting an infection and can then refuse antibiotic treatment. Please use only as directed by your doctor.

How do you use cefoperazone?

Cefoperazone is a drug that can only be obtained by prescription. Read the medication instructions provided by your pharmacist before you start using this medicine and each time you buy it again. If you have questions, ask your doctor or pharmacist.

Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

How to store this drug?

Cefoperazone is a drug that can be stored at room temperature, which is below 25 degrees Celsius. Keep away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it.

Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush cefoperazone down the toilet or down the drain unless instructed to do so. Discard this product when the drug has expired or when it is no longer needed.

Consult your pharmacist or local waste disposal agency about how to safely dispose of your medicine.

Cefoperazone dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of cefoperazone for adults?

For cases of susceptible infection, adults can take 2-4 g of cefoprazen daily in 2 divided doses. Increase to 12 g daily in 2-4 divided doses for severe infections given by injection or infusion.

What is the dose of cefoperazone for children?

Safety and effectiveness have not been established in pediatric patients (less than 18 years). For more information, consult your doctor or medical team.

In what dosage is this drug available?

Cefoperazone is available in the following forms:

• Intravenous (infusion)
• Injection

Cefoperazone side effects

What side effects can be experienced due to cefoperazone?

Just like drugs in general, cefoperazone may cause side effects of drugs in some people. The severity and symptoms of side effects may vary.

According to MIMS, some of the side effects you may have after using cefoperazone are:

• skin rash
• urticaria
• eosinophilia
• diarrhea
• nausea
• gag
• phloebitis
• the infection gets worse

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Cefoperazone Drug Warnings and Cautions

What should be known before using Cefoperazone?

Before using cefoperazone, here are a few things you need to pay attention to:

• Tell your doctor about any medications you are currently using, whether prescription, non-prescription, supplements, or herbal medicines.
• In addition, it is also important to inform your doctor about any diseases or other health conditions that you are currently suffering from.
• Tell your doctor if you have a history of drug allergy, especially to cefoperzone or other antibiotics.
• This drug has not been tested for safety in children. Before giving cefoperazone to children, first consult a doctor.
• Especially for the elderly, consult the use of this drug to your doctor first.
• This medication may affect the results of certain laboratory tests. Consult with your doctor about using this drug before undergoing any medical tests.
• Do not use this medication for longer than recommended.

Is this drug safe for pregnant and lactating women?

This drug is included in the risk of pregnancy category B according to the US Food and Drug Administration (FDA). The following references the pregnancy risk categories according to the FDA:

• A = Not at risk
• B = No risk in several studies
• C = May be risky
• D = There is positive evidence of risk
• X = Contraindicated
• N = Unknown

Studies in women show that this drug poses minimal risk to the baby when used during breastfeeding.

Cefoperazone Drug Interactions

What medicines may interact with cefoperazone?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this article.

Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Medicines that may interact with cefoperazone are:

• aminoglycoside
• furosemide
• anticoagulants or blood thinners

In such cases, the doctor may change the dose, or take other preventive measures as needed. Tell your doctor if you are taking any other over-the-counter or prescription drugs.

Can food or alcohol interact with Cefoperazone?

Certain drugs should not be used when eating certain foods because drug-food interactions can occur.

Smoking tobacco or consuming alcohol with certain drugs can also cause interactions to occur.

Discuss your use of drugs with food, alcohol, or tobacco with your doctor, nurse, or other healthcare provider.

What health conditions can interact with Cefoperazone?

The presence of other health problems in your body may affect the use of this drug. Tell your doctor if you have other health problems, such as:

• heart disease
• liver disease
• diabetes
• high blood pressure
• cystic fibrosis
• allergic to antibiotics

Cefoperazone overdose

What should I do in an emergency or overdose?

In case of emergency or overdose, call the medical team, ambulance (118 or 119), or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.