Cefoxitin: functions, dosage, side effects, how to use it

Functions & Usage

What is Cefoxitin used for?

Cefoxitin is an antibiotic drug to treat a wide variety of bacterial infections. This medication can also be used before and during certain surgeries to help prevent infection.

Cefoxitin is a drug that belongs to a class of antibiotics called cephalosporins. Cefoxitin works by stopping the growth of bacteria.

Antibiotics such as cefoxitin will not work for viral infections such as colds and flu. Using unnecessary antibiotics increases your risk of getting an infection later in life that is resistant to antibiotic treatment. Use only as directed by your doctor.

How do you use the drug Cefoxitin?

Follow the medication instructions given by your doctor or pharmacist before you start using this medicine. If you have questions, ask your doctor or pharmacist.

This medication is given by injection into a muscle or vein as directed by your doctor. Dosage is based on your medical condition and response to treatment.

If you are giving this medication to yourself at home, learn all the preparation and instructions for use from your healthcare professional. Before using it, check this product visually for particles or discoloration. If one or both of these conditions occur, do not use liquid medications. Learn how to store and dispose of medical supplies safely.

Cefoxitin is an antibiotic drug that works best when the amount of medication in your body is at a constant level. Therefore, use this drug regularly.

Continue to use this medication until the prescribed treatment period is over, even if symptoms disappear after a few days. Stopping treatment too early can result in a recurrence of the infection.

Tell your doctor if your condition does not improve or gets worse.

Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

How to store Cefoxitin?

Store the medicine at room temperature away from light and moisture. Do not store in the bathroom and freeze medication. Medicines under different brands may have different storage methods. Check the product box for instructions on how to store it, or ask the pharmacist. Stay away from children and pets.

It is forbidden to flush the medicine in the toilet or throw it into the drain if not told to. Properly discard this product if it is past the deadline or is no longer needed. Consult a pharmacist or local waste disposal company for more in-depth details on how to safely dispose of the product.

Precautions & Warnings

What should be considered before using the drug Cefoxitin?

Cefoxitin is a drug that has interactions with certain drugs. Do not use this medication if you are allergic to cefoxitin, or other cephalosporin antibiotics, such as:

• cefaclor (Raniclor)
• cefadroxil (Duricef)
• cefazolin (Ancef)
• cefdinir (Omnicef)
• Cefditoren (Spectracef)
• cefpodoxime (Vantin)
• cefprozil (Cefzil)
• seftibuten (Cedax)
• cefuroxime (Ceftin)
• cephalexin (Keflex)
• cephradine (Velosef); and others

If you have any of the other conditions, you may need a dose adjustment or special tests to make sure you are safe using cefoxitin:

• Kidney illness
• Liver disease
• Stomach disorders or intestinal disorders such as colitis
• Diabetes
• Congestive heart failure
• Cancer
• If you are malnourished

If you have had a very recent surgery or a medical emergency

Is the drug Cefoxitin safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category B according to the US Food and Drug Administration (FDA).

(A = No risk, B = No risk in some studies, C = Possible risk, D = Positive evidence of risk, X = Contraindicated, N = Unknown)

Side effects

What are the possible side effects of Cefoxitin?

Less serious side effects of cefoxitin may occur, such as:

• Nausea, vomiting, stomach pain
• Mild skin rash
• Itching or discharge in the vagina

Call your doctor if you have any of the following serious side effects:

• Diarrhea that is watery or bloody
• Fever, sore throat, and severe headache, peeling skin, and red skin rash
• Swelling, pain, or irritation where the injection was given
• Skin rash, bruising, severe tingling, numbness, pain, muscle weakness
• Feel dizzy, faint
• Easy bruising or bleeding, unusual weakness
• Fever, chills, body aches, flu symptoms
• Urinating less than usual or not at all
• Seizures
• Jaundice (eyes or skin)

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Drug Interactions

What drugs can interfere with the drug Cefoxitin?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval

Tell your doctor about all other medicines you use, especially:

• Blood thinners, such as warfarin (Coumadin, Jantoven)
• Digoxin (digitalis, Lanoxin, Lanoxicaps)
• Dipyridamole (Persantine)
• Hydroxychloroquine (Plaquenil, Quineprox)
• ibuprofen (Advil, Motrin)
• Indomethacin (Indocin)
• Cigarette nicotine, gum, lozenges, or skin patches
• Nitroglycerin (Nitro Dur, Nitrolingual, Nitrostat, Transderm Nitro, etc.)
• Antibiotics such as demeclocycline (Declomycin), doxycycline (Adoxa, Alodox, Avidoxy, Oraxyl, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn), or tetracycline (Ala-Tet, Brodspec, Panmycin, Sumycin)
• Cold, allergy, or sleeping pills (Allerest, Benadryl, Chlor-Trimeton, Dimetapp, Sominex, Tylenol PM, and others)
• Salicylates such as aspirin, Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Faucet Formula, Pepto-Bismol, TRICOSAL, Trilisate, and others.

Can certain foods and drinks interfere with the work of the Cefoxitin drug?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interfere with the performance of the drug Cefoxitin?

The presence of other health problems in your body may affect the use of this drug. Tell your doctor if you have other health problems.:

• Colitis (inflammation in the intestines), history
• Severe diarrhea, history
• Seizures - Use with caution. It might make things worse.
• Kidney disease - Use with caution. The effect can be increased because the drug clears more slowly from the body.

Dose

The information provided is not a substitute for a doctor's prescription. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of cefoxitin for adults?

Usual Adult Dose for Pneumonia:

Lower respiratory tract infections (including pneumonia and lung abscesses), urinary tract infections, intraabdominal infections (including peritonitis and intraabdominal abscesses), gynecological infections (including endometritis, pelvic cellulitis, and pelvic inflammatory disease), septicemia, bone and joint infections, and skin and skin structure infections:

infection without complications (bacteremia does not occur or does not occur) can be used as much as 1 gram of IV injection (intravenously) every 6-8 hours

Severe or severe infection can be used as much as 1 gram IV injection every 4 hours or 2 g IV every 6-8 hours

Severe, life-threatening infection: 2 g IV every 4 hours or 3 g IV every 6 hours

Usual Adult Dose for Intraabdominal Infection

Lower respiratory tract infections (including pneumonia and lung abscesses), urinary tract infections, intraabdominal infections (including peritonitis and intraabdominal abscesses), gynecological infections (including endometritis, pelvic cellulitis, and pelvic inflammatory disease), septicemia, bone and joint infections, and skin and skin structure infections:

uncomplicated infection (bacteremia absent or absent): 1 g IV every 6-8 hours

moderate or severe infection: 1 g IV every 4 hours or 2 g IV every 6-8 hours

Severe, life-threatening infection: 2 g IV every 4 hours or 3 g IV every 6 hours

Cefoxitin dose for deep vein thrombosis

Continuous IV infusion: 5000 units IV for one time use as a bolus followed by IV infusion of 1,300 units / hour continuously. Or, one time using an IV bolus of 80 units / kg followed by an IV infusion of 18 units / kg / hour.

Intermittent injection of subcutaneous tissue under the skin: 17,500 units applied to the subcutaneous tissue under the skin every 12 hours.

Dosage should be adjusted for aPTT levels at 1.5-2.5 times the control.

Cefoxitin dose for myocardial infarction

One time using 5000 units IV as a bolus followed by infusion of 1000 units / hour continuously.

Cefoxitin dosage for angina pectoris:

One time use of 5000 units IV as a bolus dose followed by a continuous infusion of 1000 units / hour.

Cefoxitin dosage for anticoagulation during pregnancy:

5000 units are used under the skin every 12 hours. This dose can be adjusted to maintain 6-hour control of aPTT 1.5 times or greater.

Cefoxitin dose for thrombosis / thromboembolic disorders:

100 units / mL every 6 to 8 hours for PVC catheter and peripheral Cefoxitin lock. Additional flow should be given when blood is stagnant in the catheter, after the catheter has been used for medicine or blood, and after blood withdrawal from the catheter.

In addition 0.5 to 1 unit / mL for central and peripheral TPN has been shown to increase the duration of patency. The arterial line was treated with Cefoxitin at a final concentration of 1 unit / mL

What is the dose of cefoxitin for children?

3 months or more: 80-160 mg / kg / day IV divided in 4-6 equal doses. Maximum dose: 12 g / day.

In what dosages and preparations is Carbocisteine ​​available?

Cefoxitin is available in the following dosage forms and levels:

• Solution, intravenous (IV): 1g, 2g
• Solution, Injection: 10g

What to do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (119) or immediately to the nearest hospital emergency department.

What should I do if I forget to take medicine or forget to take medicine?

If you forget a dose of this medicine, use it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical consultation, diagnosis or treatment.