Ciclosporin: functions, dosage, side effects, how to use

What drug ciclosporin?

What is ciclosporin for?

Ciclosporin is an immunosuppressant drug. This drug works by slowing down the immune system to prevent your body from rejecting transplanted organs such as a liver, kidney, heart, cornea, pancreas, or bone marrow transplant. Not only that, ciclosporin can also be used to treat various health conditions that affect the immune system, such as Crohn's disease and culative colitis.

Usually this medicine is used in conjunction with other medicines to allow your new organs to function normally.

How to use the drug ciclosporin?

Before using this medicine or every time you buy it again, always read the instructions for using the medicine listed on the package or the information brochure provided at the pharmacy. If you have further questions, please ask your doctor or pharmacist.

How is the drug ciclosporin stored?

Ciclosporin is a drug that must be stored at room temperature. Keep this drug away from direct sun exposure and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Ciclosporin dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of ciclosporin for adults?

For oral treatment after organ transplantation, the dosage of ciclosporin is:

• The initial dose, 10-15 mg / kg / day, is started 4-12 hours before the procedure and continued for 1-2 weeks
• Adjusted dose, 2-6 mg / kg / day

Lower doses can be used when the drug is combined with other immunosuppressant drugs

For the oral treatment of severe atopic dermatitis, the dosage of ciclosporin is:

• The initial dose, 2.5 mg / kg / day, is divided into two doses
• Maxima dose: 5mg / kg / day

For the treatment of oral psoriasis, ciclosporin dosages are:

• The initial dose, 2.5 mg / kg / day, is divided into two doses
• Maximum dose, 5 mg / kg / day

For the oral treatment of rheumatoid arthritis, ciclosporin dosages are:

• The initial dose, 2.5 mg / kg / day, is divided into two doses
• Maximum dose, 4 mg / kg / day

For oral treatment gnephrotile symptoms, ciclosporin dosages are:

• The starting dose, 5mg / kg per day, is divided into two doses.

For intravenous (infusion) treatment after organ transplantation, the dose of ciclosporin is:

• Initial dose, 5-6 mg / kg / day in the first dose, infusion dose for 2-6 hours. Change to an oral dose as soon as possible.

What is the dose of ciclosporin for children?

For the oral treatment of nephrotic symptoms, the dose of ciclosporin is 6mg / kg daily, which is divided into 2 doses.

In what dosage is ciclosporin available?

• Capsule
• Drinking medicine
• Intervenous (infusion)

Ciclosporin side effects

What side effects can be experienced from the drug ciclosporin?

The side effects that can be caused by using this drug include:

• Hypertension
• Hepotoxicity
• Tremor
• Tingling sensation
• Hypertrichosis
• Facial edema
• Acne
• Gingival hypertrophy (gum disorders due to blood disease)
• Hyperkalaemia
• Indigestion

Not everyone experiences this side effect. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Cyclosporin Drug Warnings and Cautions

What should be known before using the drug ciclosporin?

You should tell your doctor if you have:

• Kidney and liver disorders
• Hyperuricaemial anaphylaxis
• Allergy symptoms
• Pregnant and breastfeeding

Is ciclosporin safe for pregnant and lactating women?

There is no adequate research on the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA).

The following references the pregnancy risk categories according to the FDA:

• A = Not at risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated,
• N = Unknown

Ciclosporin Drug Interactions

What medicines may interact with the drug ciclosporin?

Although some drugs should not be taken at the same time, in other cases some drugs can also be used together even though interactions may occur. In such cases, the doctor may change the dose, or take other preventive measures as needed. Tell your doctor if you are taking any other over-the-counter or prescription drugs.

Can food or alcohol interact with the drug ciclosporin?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions may interact with the drug ciclosporin?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems.

Ciclosporin overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.