Corticorelin: functions, dosage, side effects, how to use it

What is Corticorelin?

What is corticorelin for?

Corticorelin is a drug used as part of a medical test for people with Cushing's syndrome. Cushing's syndrome is caused by high levels of cortisol (a steroid hormone produced by the adrenal glands).

Corticorelin is a drug that is also used to help doctors determine why your body is producing too much cortisol.

Corticorelin dosage

How is corticorelin used?

Corticorelin is a drug that is used by injection into a vein through an IV. The health care provider will give this injection in a hospital or clinic.

Corticorelin is usually given as a single injection for the corticorelin test. Your healthcare provider will need at least 5 blood samples from you before and after you receive your medicine.

In most cases, blood is tested 15 minutes before injection and right before you receive an injection. This test will give the doctor two measurement conditions.

After you receive corticorelin, your blood will be drawn again 15 minutes, 30 minutes, and 60 minutes after the injection. This method will help your doctor further diagnose your condition.

The timing of blood tests before and after the injection is very important in ensuring the most accurate results of the corticorelin test. Plan to be in health care, at least 1 hour after your injection.

Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

How is corticorelin stored?

Corticorelin is a drug that is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Corticorelin side effects

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of corticorelin for adults?

Corticorelin is a drug that can be used with the following rules:

• Maintenance dose: 1 mcg / kg intravenously for every 30 seconds
• Maximum dose: Doses greater than 1 mcg / kg are not recommended.

Important to note! Some of the side effects can be reduced by administering the drug as an infusion for more than 30 seconds, not as a bolus injection.

Usage: differentiate pituitary and ectopic ACTH production in patients with ACTH-dependent Cushing's syndrome.

What is the dose of corticorelin for children?

Corticorelin is a drug that can be used with the following rules:

• Maintenance dose: 1 mcg / kg intravenously for every 30 seconds
• Maximum dose: Doses greater than 1 mcg / kg are not recommended.

Important to note! Some of the side effects can be reduced by administering the drug as an infusion for more than 30 seconds, not as a bolus injection.

Usage: Distinguish pituitary and ectopic ACTH production in patients with ACTH-dependent Cushing's syndrome.

In what dosage is corticorelin available?

Corticorelin is a drug that is available as an injectable liquid.

Corticorelin Drug Warnings and Cautions

What side effects can be experienced due to corticorelin?

Corticorelin is a drug that can cause side effects. Get emergency medical help if you have signs of this allergic reaction such as: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.

Tell your doctor if you feel like you might pass out, or if you have:

• rapid heart rate
• a feeling of tightness in your chest
• if you feel like you need to take a deep breath.

Less serious side effects may include warmth, redness, or a tingling feeling in the face, neck, or chest.

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Corticorelin Drug Interactions

What should be known before using corticorelin?

Before you receive this medicine, tell your doctor about all your medical conditions and allergies.

Is corticorelin safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the Food and Drug Administration in the United States (BPOM).

Following are references to pregnancy risk categories according to the Food and Drug Administration in the United States (BPOM):

• A = No risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated,
• N = Unknown

Corticorelin overdose

What medications might interact with corticorelin?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval

Although certain drugs should not be used at the same time, in other cases two different drugs can be used together even if interactions are possible. In this case, your doctor may want to change the dose or take other precautions that may be needed. Tell your health care professional if you are taking any other prescription or nonprescription drugs on the market.

Can food or alcohol interact with corticorelin?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with corticorelin?

The presence of other health problems in your body may affect the use of this drug. Tell your doctor if you have other health problems.

Overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.