Ergometrine: functions, dosage, side effects, how to use

What Drug Ergometrine?

What is ergometrine for?

Ergometrine is generally used to prevent and treat bleeding after childbirth or abortion. Can also be used for other conditions as directed by the doctor.

Ergonovine is a uterine stimulant. Ergonovine works by increasing uterine contractions, which can reduce blood loss after delivery.

How should I use ergometrine?

Follow the rules given by your doctor or pharmacist before starting treatment. Check the label on the package for precise dosing instructions. Ergonovine can be used with or without food. Eating grapefruit or grapefruit juice can affect Ergonovine levels in the blood. Tell your doctor before consuming grapefruit. Do not use Ergonovine for more than 1 week, unless instructed by your doctor. Ask your healthcare provider how to use Ergonovine.

How is ergometrine stored?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Ergometrine Usage Rules

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of ergometrine for adults?

Oral

Postpartum and post-abortion bleeding

0.2 - 0.4 mg 2 to 4 times daily until the danger of uterine atony and bleeding is gone (usually 48 hours). Maximum duration: 1 week postpartum.

Intramuscular
Management is active at the third level in labor
500 mcg is given with 5 units of oxytocin after delivery of the baby's anterior shoulder or immediately after delivery.

Intravenous
Excessive bleeding in the uterus

200 mcg by IV infusion for at least 1 minute. Can be continued with a drinking dose of 200-400 mch 2-4 times a day until the danger of uterine atony and bleeding disappears (usually 48 hours).

Intramuscular
Postpartum hemorrhage treatment and prophylaxis

200 mcg, can be repeated for severe bleeding every 2-4 hours as needed.

What is the dose of ergometrine for children?

There is no provision for the dosage of this drug for children. This medicine can be dangerous for children. It is important to understand the safety of drugs before use. Consult your doctor or pharmacist for more information.

In what dosage is ergometrine available?

Ergometrine is available in the following dosages.

Tablet: 0.2 mg

Solution: 500 mcg / mL

Ergometrine dosage

What side effects can be experienced due to ergometrine?

Medications can cause side effects, but most people do not experience, or experience minor side effects. Ask your doctor if any of the common side effects below persist or are bothering you:

• uterine cramps

Seek immediate medical help if you experience the following signs of an allergic reaction:

• severe allergic reaction (rash, hives, difficulty breathing, tightness in the chest, swelling of the face, lips, tongue, or throat); blood in the urine, pain or tightness in the chest; diarrhea; dizzy; hallucinations; headache; irregular heartbeat; leg cramps; mental or mood changes; numbness or tingling of the hands, feet or skin; ear rings; seizures; severe nausea or vomiting; hard to breathe.

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Ergometrine side effects

What should be known before using ergometrine?

Before using Ergometrine, tell your doctor if:

• You have an allergy to the composition of Ergonovine
• You are pregnant
• You are currently taking HIV protease inhibitors (delavirdine, indinavir, nelfinavir, ritonavir), efavirenz, a ketolide antibiotic (eg, telithromycin), a macrolide antibiotic (eg, clarithromycin, erythromycin), or selective 5-HT agonists (eg, sumatriptan, eletriptan)

Is ergometrine safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA).

The following references the pregnancy risk categories according to the FDA:

• A = No risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated,
• N = Unknown

Ergometrine has been detected in breast milk, but does not appear to affect breastfed babies.

Ergometrine Drug Warnings and Cautions

What drugs may interact with ergometrine?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Although some drugs should not be taken at the same time, in other cases some drugs can also be used together even though interactions may occur. In such cases, the doctor may change the dose, or take other preventive measures as needed. Tell your doctor if you are taking any other over-the-counter or prescription drugs.

Using this medication with some of the medicines below is not usually recommended, but in some cases it may be necessary. If both drugs are prescribed for you, your doctor will usually change the dosage or determine how often you should take them.

• Azole antifungals (itraconazole, ketoconazole, voriconazole), clotrimazole, ergot alkaloids (ergotamine), fluconazole, fluoxetine, fluvoxamine, nefazodone, saquinavir, or zileuton because side effects of ergonovine can increase
• HIV protease inhibitors (delavirdine, indinavir, nelfinavir, ritonavir), efavirenz, ketolide antibiotics (telithromycin), macrolide antibiotics (erythromycin, clarithromycin), or selective 5-HT agonists (esumatriptan, eletriptan) because of the risk of severe side effects, such as heartbeat An irregular or depletion of oxygen to the extremities (hands, feet) or brain, can increase

Can food or alcohol interact with ergometrine?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with ergometrine?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

• if you are pregnant, planning to become pregnant or are breastfeeding
• if you are taking medications, herbal products or dietary supplements
• if you have an allergy to drugs, food or other ingredients
• if you have a blood infection or a history of blood vessel problems, blood problems (porphyria), high blood pressure, stroke, liver problems, kidney problems, low blood calcium levels or heart problems
• if you have eclampsia or preeclampsia.

Ergometrine Drug Interactions

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

Overdose symptoms can include chest pain, coma, diarrhea, difficulty breathing, nausea, numbness, chills, tingling, seizures, severe headache or dizziness, vomiting, weak pulse.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.