Table of contents:
- Functions & Usage
- What is Exenatide used for?
- What are the rules for using Exenatide drugs?
- How do I save Exenatide?
- Precautions & Warnings
- What should be considered before using Exenatide drugs?
- Is Exenatide safe for pregnant and breastfeeding women?
- Side effects
- What are the possible side effects of Exenatide?
- Drug Interactions
- What drugs can interfere with the drug Exenatide?
- Can certain foods and drinks interfere with the action of Exenatide drugs?
- What health conditions can interfere with the performance of the drug Exenatide?
- Dose
- What is the dosage of Exenatide for adults?
- What is the dosage of Exenatide for children?
- In what dosages and preparations Exenatide is available?
- What to do in an emergency or overdose?
- What should I do if I forget to take medicine or forget to take medicine?
Functions & Usage
What is Exenatide used for?
Exenatide is a drug to control high blood sugar in people who have type 2 diabetes. Exenatide is best used in conjunction with a proper diet and exercise program. Controlling high blood sugar can help prevent kidney damage, blindness, nerve problems, loss of limbs, and problems with sexual function. Proper diabetes control can also reduce the risk of heart attack or stroke.
Exenatide belongs to a class of drugs known as anti-diabetes drugs. This drug acts similar to a natural hormone in the body (incretin). This medication works by increasing insulin release (especially after a meal) and reducing the amount of sugar made by your liver. This medication also slows down the digestion of food in your stomach, reduces the amount of sugar absorbed from food, and can help reduce your appetite.
What are the rules for using Exenatide drugs?
Follow the medication instructions given by your doctor or pharmacist before you start using this medicine. If you have questions, ask your doctor or pharmacist.
Before using this medication, please check the visual state of this product. If there are particles or discoloration, do not use this medicinal liquid. Before injecting each dose, clean the injection area with alcohol. Change the injection area with each dose to reduce injury under the skin.
Inject this medication under the skin of your thigh, stomach, or upper arm as directed by your doctor, usually twice daily. The injection should be done within 60 minutes before breakfast and dinner (or before the two main meals of the day, at least 6 hours apart). Exenatide should not be used after eating because it will not work properly.
If you are also taking insulin, give exenatide and insulin as separate injections. Don't mix it up. You may inject these medications in the same area of your body, but the injection areas don't have to be next to each other.
Because exenatide can slow down the digestion of food or drugs in your stomach, certain medications (such as birth control pills, taking antibiotics) may not work very well if you take them at the same time. Take birth control pills or antibiotics at least 1 hour before using exenatide. If you must take any of these medicines with food, take them with meals or snacks when you are not taking exenatide. Ask your doctor or pharmacist if you have questions about when to use your medicine.
Dosage is based on your medical condition and response to treatment. Use this remedy regularly to get its benefits. To help you remember, use it at the same time every day. Be careful about following your diabetes management plan, including medications, diet, and exercise.
Check your blood sugar regularly as directed by your doctor. Watch the results and tell your doctor. Tell your doctor if your blood sugar measurement is often too high or too low. Your doctor may need to adjust your diabetes medications, exercise program, or diet.
Learn how to store and dispose of medical supplies safely. Consult the pharmacist for more details. Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.
How do I save Exenatide?
This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.
Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.
Precautions & Warnings
What should be considered before using Exenatide drugs?
Before using Exenatide,
- Tell your doctor and pharmacist if you are allergic to exenatide or any other medications.
- Tell your doctor and pharmacist about prescription drugs, nonprescription drugs, vitamins, nutritional supplements, and herbal products that you use or plan to use. Be sure to name one of the following: enzyme (ACE) angiotensin-converting inhibitor such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril, (Aceon), quinapril (Accupril), ramipril (Altace), and Trandolapril (Mavik); diuretics ('water pills'); aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); medications for high blood pressure; sulfonylureas such as chlorpropamide (Diabinese), glimepiride (Amaryl), glipizide (Glucotrol), glyburide (DiaBeta, Micronase), tolazamide, and tolbutamide; and warfarin (Coumadin).
- if you are using oral contraceptives (birth control pills) or antibiotics, take them at least 1 hour before you use the exenatide injection. If you have been told to take any of these medicines with food, take them with meals or snacks when you are not taking exenatide.
- Tell your doctor if you drink or have been drunk alcohol and if you experience nausea, vomiting, and diarrhea or think you may be dehydrated or if you experience any of these symptoms at any time during your treatment. Additionally tell your doctor if you have or have ever had pancreatitis (swelling of the pancreas), gallstones (solid deposits that form in the gallbladder), high levels of triglycerides (fat) in the blood; severe stomach problems; high blood pressure; or kidney disease.
- Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while using exenatide, call your doctor.
- Ask your doctor about the safe use of alcoholic beverages while you are using exenatide
Is Exenatide safe for pregnant and breastfeeding women?
There is no adequate research on the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA). (A = No risk, B = No risk in some studies, C = Possible risk, D = Positive evidence of risk, X = Contraindicated, N = Unknown)
Studies in women show that this drug poses minimal risk to the baby when used during breastfeeding.
Side effects
What are the possible side effects of Exenatide?
Get emergency medical help if you have any of these signs of an allergic reaction: nausea, vomiting, sweating, hives, itching, difficulty breathing, swelling of your face, lips, tongue, or throat, or feel like you might pass out.
Call your doctor if you have any of the following serious side effects:
- Swelling in the neck or throat (enlarged thyroid), hoarseness, difficulty swallowing or breathing;
- Swelling, weight gain, feeling short of breath, urinating less than usual or not at all;
- Drowsiness, confusion, mood changes, increased thirst, diarrhea;
- Pain in the middle or lower back;
- Severe pain in the upper abdomen that spreads to the back, vomiting; or
- Low blood sugar (headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling restless).
Less serious side effects may include:
- Nausea, stomach pain, diarrhea or constipation
- Weight loss
- Feeling itchy or a hard lump where the medicine was injected
Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.
Drug Interactions
What drugs can interfere with the drug Exenatide?
Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval
Using this medication with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If the two drugs are prescribed together, your doctor may change the dose or adjust how often you use one or both drugs.
- Digoxin
- Warfarin
Can certain foods and drinks interfere with the action of Exenatide drugs?
Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.
What health conditions can interfere with the performance of the drug Exenatide?
The presence of other health problems in your body may affect the use of this medicine. Tell your doctor if you have other health problems.:
- Diabetic ketoacidosis (ketones in the blood) or
- Type 1 diabetes - Should not be used in patients with this condition. Insulin is needed to control this condition.
- Gallstones
- Kidney disease (including kidney transplant)
- Pancreatitis (inflammation of the pancreas), history
- Thyroid tumors - Use with caution. It might make things worse.
- Gastroparesis (not emptying the stomach normally)
- Severe kidney disease
- Multiple endocrine neoplasia syndrome type 2 (MEN 2) or
- Stomach or intestinal disease, severe or
- Thyroid cancer, history - should not be used in patients with this condition.
Dose
The information provided is not a substitute for a doctor's prescription. ALWAYS consult your doctor or pharmacist before starting treatment.
What is the dosage of Exenatide for adults?
Usual Adult Dose for Type 2 Diabetes
Subcutaneous solution: 5 micrograms subcutaneously twice daily for a 60-minute period before breakfast and dinner. Exenatide should not be given after a meal. Based on clinical response, the dose can be increased to 10 micrograms twice daily after 1 month of therapy.
Subcutaneous powder for injections, extended release: 2 mg subcutaneously once every seven days (a week), at any time of day and with or without food. Use immediately after the powder is dissolved.
What is the dosage of Exenatide for children?
The dosage has not been established in pediatric patients. This medicine may not be safe for your child. It is always important to understand the safety of drugs before using them. Please consult a doctor or pharmacist for more information.
In what dosages and preparations Exenatide is available?
Solution, subcutaneous: 10 mcg / 0.04 mL (2.4 mL), 5 mcg / 0.02 mL (1.2 mL)
Suspension, subcutaneous: 2 mg
What to do in an emergency or overdose?
In case of an emergency or overdose, contact the local emergency services provider (119) or immediately to the nearest hospital emergency department.
Overdose symptoms may include:
- Severe stomach pain
- Severe vomiting
- Dizzy
- Symptoms of hypoglycemia
What should I do if I forget to take medicine or forget to take medicine?
If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.
Hello Health Group does not provide medical consultation, diagnosis or treatment.