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Gofen 400: functions, dosage, side effects, how to use it

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Use

What is the function of Gofen 400?

Gofen 400 is a drug used to relieve pain associated with colds, flu, headaches, toothaches, muscle pain, back pain, minor pain from arthritis, menstrual pain (dysmenorrhea) and fever.

How do you use Gofen 400?

Use the medication exactly as directed on the label, or as prescribed by your doctor. Do not use in amounts greater than or for longer than recommended. Use the lowest dose that is effective in treating your condition.

Do not take more than the recommended dose. An ibuprofen overdose can damage the stomach or intestines. The maximum amount of ibuprofen for adults is 800 milligrams per dose or 3200 mg per day (4 doses maximum). Use only the smallest amount necessary to relieve your pain, swelling, or fever.

The dose of ibuprofen for a child is based on the child's age and body weight. Carefully follow the dosage instructions provided with your child's medicine for your child's age and weight. Ask your doctor or pharmacist if you have any questions.

Take ibuprofen with food or milk to reduce stomach pain.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

How to store Gofen 400?

In dry conditions protected from light, at temperatures below 25 ° C. Expiration date for Gofen 400: 3 years.

Warning

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What should I pay attention to before using Gofen 400?

This drug should be used with caution in patients with kidney disease, chronic heart failure, dyspepsia symptoms before treatment, used immediately after surgery, with indications of a history of gastrointestinal bleeding in gastrointestinal diseases, allergic reactions associated with the use of NSAIDs.

Be careful using this medicine if you have liver and stool disease. Do not use as an external medicine on injured skin.

This medicine may increase your risk of fatal heart attack or stroke, especially if you use it long-term or take high doses, or if you have heart disease. Even people without heart disease or risk factors can have a stroke or heart attack while on this medicine.

Do not use this medication before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Ibuprofen can also cause stomach or intestinal bleeding, which can be fatal. This condition can occur without warning when you are using ibuprofen, especially in the elderly.

You should not use Gofen 400 if you are allergic to ibuprofen, or if you have had an asthma attack or a severe allergic reaction after taking aspirin or an NSAID.

Is Gofen 400 safe for pregnant and lactating women?

Do not use this medication in the third trimester of pregnancy. Use in the I and II trimesters of pregnancy is justified only in cases where it is hoped that the drug will have more benefit to the mother than any possible harm to the fetus.

Ibuprofen in small amounts is mixed into breast milk. You are usually allowed to use this drug during lactation to reduce pain and fever. If this medicine has to be used in a long-term or high dose (800 mg / 24 hours) medication, you should stop breastfeeding.

Side effects

What are the possible side effects of Gofen 400?

  • Digestive system: frequent nausea, anorexia, vomiting, discomfort in the epigastrium, diarrhea, may lead to erosions and ulcerative sores in the digestive tract; rare bleeding from the gastrointestinal tract, possibly triggering liver problems when used long term.
  • Central nervous system and peripheral nervous system: frequent headaches, dizziness, sleep disturbances, agitation, visual disturbances.
  • Hemopoietic system: long-term use may cause anemia, thrombocytopenia, agranulocytosis.
  • Urinary tract: long-term use may cause kidney dysfunction
  • Allergic reactions: frequent skin rashes, edema, rare aseptic meningitis (usually in patients with autoimmune diseases), bronchospasm syndrome.
  • Local reactions: when topical drugs are used it may cause skin hyperemia, skin burning or tingling.

Drug Interactions

What medicines should not be taken at the same time as Gofen 400?

  • Simultaneous use with ibuprofen can reduce the effects of antihypertensive drugs (ACE inhibitors, beta-blockers), diuretics (furosemide, hypothiazide).
  • Simultaneous use with anticoagulants can increase the effect.
  • Simultaneous use with SCS increases the risk of side effects from the gastrointestinal tract.
  • Simultaneous use can replace the compound with an indirect anticoagulant plasma protein (acenocoumarol), a derivative of hydantoin (phenytoin), a sulfonylurea derivative oral hypoglycemic drug.
  • Simultaneous use of amlodipine may slightly reduce the antihypertensive action of amlodipine, with acetylsalicylic acid: decrease the concentration of ibuprofen in the blood plasma, with baclofen: increase the toxicity of baclofen.
  • When used together with warfarin can increase bleeding time, as well as microhematuria, bruising with hydrochlorothiazide: maybe a slight decrease in the antihypertensive action of hydrochlorothiazide, captopril: can reduce the antihypertensive effect of captopril, with cholestyramine: decrease the absorption of ibuprofen.
  • Simultaneous use with lithium carbonate increases the concentration of lithium in blood plasma.
  • Simultaneous use with magnesium hydroxide can increase the initial absorption of ibuprofen, with methotrexate can increase methotrexate toxicity.

Are there foods and drinks that should not be consumed when using Gofen 400?

Ask your doctor before using Ibuprofen along with ethanol. Do not drink alcohol while taking Ibuprofen. Alcohol can increase the risk of stomach bleeding caused by ibuprofen. Call your doctor if you have symptoms of bleeding in the stomach or intestines. These include black, bloody, or tar-like stools, or coughing up blood or vomiting that looks like coffee grounds. It is highly recommended to tell your doctor about all other medicines you use, including vitamins and herbs. Do not stop using any medication without first consulting your doctor.

Fluid retention and edema have been reported in association with the use of nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs should be given with caution in patients with pre-existing fluid retention, hypertension, or a history of heart failure. Blood pressure and cardiovascular status should be monitored during the initiation of NSAID treatment and throughout therapy.

Dose

The following information cannot be used as a substitute for a doctor's prescription. You MUST consult your doctor or pharmacist before using Gofen 400.

What is the dosage of Gofen 400 for adults?

Take 1 capsule every 4-6 hours when symptoms occur.

The maximum daily dose for adults when given orally is 2.4 g.

Rheumatoid arthritis: 0.8 g 3 times a day.

Osteoarthrosis and ankylosing spondylitis: 0.4-0.6 grams, 3-4 times a day.

What is the dosage of Gofen 400 for children?

Children over 12 years: 1 capsule every 4-6 hours when symptoms occur.

Juvenile rheumatoid arthritis - 30-40 mg / kg / day in several stages.

But do not exceed 3 capsules in 24 hours unless directed by a doctor.

In what forms is Gofen 400 available?

This drug is available in 400 mg Softgel capsules.

What should I do in an emergency or overdose?

In case of an overdose, immediately call the local emergency services or rush to the hospital.

Overdose symptoms may include: dizziness; fast eye movements that you can't control; breathing slowly or not breathing for short periods of time; lips, mouth and nose are bluish in color.

What should I do if I forget to take / take medicine?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Gofen 400: functions, dosage, side effects, how to use it
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