Griseofulvin: functions, dosage, side effects, how to use

What drug Griseofulvin?

What is griseofulvin used for?

Griseofulvin is a type of antifungal drug. This drug is generally available in tablet form. Griseofulvin works by fighting infections in the body caused by the presence of fungi.

Griseofulvin is commonly used to treat infections such as ringworm, athlete's foot, jock itch, and fungal infections of the scalp, fingernails, or toenails.

This medicine is included in a prescription drug, so you can only get it if it is accompanied by a prescription from your doctor. Griseofulvin can also be used for things other than those not listed in this article.

How do you use griseofulvin?

Here's how to use griseofulvin:

• Follow the rules on the recipe label. Do not use more or less or the longer recommended amount.
• Shake the oral suspension (liquid) before using this medication.
• Measure liquid medicine with the medicine gauge provided, or with a special measuring spoon or dose medicine cup . If you do not have a dose measuring device, ask your pharmacist.
• For easy swallowing, you can crush a Gris-PEG tablet and sprinkle it on a yogurt spoon. Swallow the medicine without chewing. Do not save the medicinal mixture for future use.
• Use this medicine until it runs out. For your symptoms to improve, it can take up to several weeks. Nail infections can take several months to completely heal.
• Griseofulvin does not treat bacterial infections, or viral infections such as the flu.
• If you are using this medicine long-term, you may need frequent medical tests at the doctor's office.
• Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

How to store this drug?

Griseofulvin is best stored at room temperature, away from direct light and damp places. Do not store in the bathroom and do not freeze. Other brands of this drug may have different storage rules.

Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed.

Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Griseofulvin dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the griseofulvin dosage for adults?

The following is the griseofulvin dosage for adults:

Adult dose for onychomycosis - fingernails

• Ultramicrosize formula: 660-750 mg / day orally in 2-4 separate doses.
• Microsize formula: 1000 mg / day taken in 2-4 separate doses.

Adult dose for onychomycosis - toenails

• Microsize formula: 1000 mg / day orally in 2-4 separate doses.
• Ultramicrosize Formula: 660-750 mg / day orally in 2-4 separate doses.

Adult dosage for tinea pedis

• Microsize formula: 1000 mg / day orally in 2-4 separate doses.
• Ultramicrosize Formula: 660-750 mg / day orally in 2-4 separate doses.

Adult dosage for tinea barbae

• Microsize formula: 500 mg / day orally in a single dose or 2 separate doses.
• Ultramicrosize Formula: 330-375 mg / day orally in single dose or separate dose.

Adult dosage for tinea capitis

• Microsize formula: 500 mg / day orally in a single dose or 2 separate doses.
• Ultramicrosize Formula: 330-375 mg / day orally in single dose or separate dose.

Adult dosage for tinea corporis

• Microsize formula: 500 mg / day orally in a single dose or 2 separate doses.
• Ultramicrosize Formula: 330-375 mg / day orally in single dose or separate dose.

Adult dosage for tinea cruris

• Microsize formula: 500 mg / day orally in a single dose or 2 separate doses.
• Ultramicrosize Formula: 330-375 mg / day orally in single dose or separate dose.

What is the dose of griseofulvin for children?

Here is the griseofulvin dosage for children:

Child dosage for dermatophytosis

• Microsize Formula:
  ≥ 1 year: 10-20 mg / kg / day orally in single or divided doses, not more than 1000 mg / day
• Ultramicrosize Formula:
  ≤ 2 years: Dosage unknown.
  over 2 years: 5-15 mg / kg / day in single or divided doses, not more than 750 mg / day

In what dosage is this drug available?

Griseofulvin is available in the following dosages.

Suspension, Oral: 125 mg / 5mL (118 mL, 120 mL)
Tablet, Oral: 125 mg, 250 mg, 500 mg

Griseofulvin side effects

What side effects can be experienced due to griseofulvin?

Seek emergency medical help immediately if you experience signs of an allergic reaction:

• itchy rash
• difficulty breathing
• swelling of the face, lips, tongue, or throat

In addition, there are several possible side effects ranging from mild to serious health conditions. Call your doctor if you have serious side effects such as:

• fever, chills, flu symptoms
• white or painful spots in your mouth or on your lips
• confused, problems in carrying out daily activities
• nausea, upper abdominal pain, itching, no appetite, dark urine, putty bowel movements, jaundice (yellowing of the skin or eyes)
• a serious allergic reaction such as fever, sore throat, swelling of the face or tongue, burning in the eyes, skin pain, followed by a red or purple skin rash that spreads (especially on the face or upper body) and causes blisters and peeling.

However, there are also less severe side effects, namely:

• flushing (feeling of warmth, redness, or tingling)
• nausea, vomiting, or diarrhea
• headache, drowsiness, feeling tired
• sleep problems (insomnia)
• Confused or dazed
• numbness or tingling in your hands or feet
• irregular menstruation.

Not everyone experiences the following side effects. There may be some side effects not listed above.

If you have concerns about certain side effects, consult your doctor or pharmacist.

Griseofulvin Drug Warnings and Cautions

What should be known before using griseofulvin?

Before using griseofulvin, there are a few things you should do, including:

• Tell your doctor and pharmacist if you are allergic to griseofulvin, or any other medications.
• Tell your doctor and pharmacist what prescription and nonprescription drugs you are taking.
• Tell your doctor if you have or have had liver disease, porphyria, lupus, or a history of alcohol abuse.
• Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant and are taking griseofulvin, call your doctor right away.
• Tell your doctor if you consume alcohol.
• Avoid unnecessary or prolonged sun exposure and wear protective clothing, sunglasses, and sunscreen. Griseofulvin can make your skin sensitive to the sun.

Is griseofulvin safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication.

This drug is included in the risk of pregnancy category X according to the US Food and Drug Administration (FDA) or the equivalent of the Food and Drug Administration (BPOM) in Indonesia. The following references the pregnancy risk categories according to the FDA:

• A = No risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated,
• N = Unknown

Griseofulvin Drug Interactions

What medicines might interact with griseofulvin?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document.

Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Drug interactions can increase your risk of serious side effects, but using both drugs may be the best treatment alternative for you. If the two drugs are prescribed together, your doctor may have changed the dose or frequency of use of one or both drugs.

• Desogestrel
• Dienogest
• Drospirenone
• Estradiol Cypionate
• Estradiol Valerate
• Ethinyl Estradiol
• Ethynodiol Diacetate
• Etonogestrel
• Levonorgestrel
• Medroxyprogesterone Acetate
• Mestranol
• Norelgestromin
• Norethindrone
• Norgestimate
• Norgestrel
• Phenobarbital
• Warfarin

Can food or alcohol interact with griseofulvin?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur.

Smoking tobacco or consuming alcohol with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with griseofulvin?

The presence of other health problems in your body may affect the use of this drug. Tell your doctor if you have other health problems, in particular:

• actinomycosis (bacterial infection)
• blastomycosis (Gilchrist's disease)
• candidiasis (yeast infection)
• histoplasmosis (Darling's disease)
• other infections (such as bacteria)
• sporotrichosis (Rose gardener's disease)
• tinea versicolor (Tinea flava). Griseofulvin will not work in patients with this condition
• heart failure
• porphyria (enzyme problems). This medicine should not be used in patients with this condition.
• lupus erythematosus or a lupus-like disease. Use with caution as it can worsen the condition.

Griseofulvin overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.