Isosorbide mononitrate: functions, dosage, side effects, how to use

Isosorbide Mononitrate What Drug?

What is isosorbide mononitrate for?

Isosorbide mononitrate is a drug to prevent angina pectoris attacks in people with coronary heart disease.

Angina is pain or discomfort in the chest due to lack of blood flow to the heart. This condition is caused due to narrowing or blockage of blood vessels in the body. Ordinary people are more familiar with sitting wind disease.

Isosorbide mononitrate belongs to the nitrate drug class. This drug works to relax blood vessels to improve blood circulation and facilitate the work of the heart.

In certain cases, this drug is also an adjunct therapy to treat congestive heart failure. This medication can also help lower blood pressure because it can dilate narrowed blood vessels.

This medicine cannot treat angina attacks that have already occurred. In addition, this drug is also ineffective at preventing chest pain if taken just before exercise or other physical activity.

These drugs are only available by prescription. Therefore, do not try to use this drug without your doctor's approval.

How do I use isosorbide mononitrate?

Here are the rules for taking Isosorbide mononitrate that you need to pay close attention to:

• Take this medication exactly as prescribed by your doctor or what is stated on the label on the package.
• Take this medication 30 minutes before meals, or on an empty stomach.
• Do not chew, crush, or crush the medicine. Swallow the drug whole with the help of a glass of water. Chewing or grinding the medicine can decrease its effectiveness.
• Your doctor may change the dose of your medication every now and then so that you can get optimal benefits.
• Do not add or reduce doses of medication without your doctor's knowledge. you, too
• Take medication regularly to get maximum benefits. To help you remember, take this medication at the same time each day.
• If you forget to take this drug, take it immediately if the interval from your next drinking schedule is not too close. Meanwhile, when it is close, ignore it and do not take double doses of medicine.
• If possible, try to rest or sit while you are taking this medicine. This is because this drug can cause dizziness or even fainting.
• You should not drive or operate heavy machinery after using this medicine. Also avoid getting up or standing up suddenly to prevent the risk of falling.
• You should not stop using the drug suddenly if the reason you are taking this medicine is to relieve angina attacks. The reason is, this can put you at risk of having a severe angina attack.
• If the symptoms continue to get worse, do not hesitate to seek medical care.

How is isosorbide mononitrate stored?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules.

Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Isosorbide Mononitrate Dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage for isosorbide mononitrate for adults?

The initial dose of 20 mg is taken 2-3 times a day. This drug can also be given in a dose of 40 mg orally twice a day.

Especially for patients who have never taken nitrate drugs at all, a dose of 10 mg can be given orally 2 times a day.

If needed, patients can also take this drug up to 120 mg a day, which is taken several times a day.

In principle, each person may get different doses of drugs. The dosage of the drug must be according to the doctor's prescription. Taking the drug at random doses can increase the risk of dangerous side effects that can be fatal.

The doctor will provide a drug dose according to age, overall health condition, and the patient's response to treatment.

What is the dose of isosorbide mononitrate for children?

There is no provision for the dosage of this drug for children. This medicine can be dangerous for children. It is important to understand the safety of drugs before use. Consult your doctor or pharmacist for more information.

In what dosage is isosorbide mononitrate available?

This drug is available in the form of film-coated tablets in doses of 30 mg, 60 mg, 120 mg.

Isosorbide Mononitrate side effects

What side effects can be experienced due to isosorbide mononitrate?

Every drug in principle has the potential to cause side effects, including this drug. Some of the side effects that can arise from using this drug include:

• Nausea
• Gag
• Constipation
• Diarrhea
• Bloated
• Discomfort in the stomach
• Dizziness or headache
• Heart palpitations
• Feelings of restlessness
• Low blood pressure
• Kliyengan
• Tingling sensation
• Red skin
• Pain in the leg joints or muscles
• Vertigo
• Back pain
• Hot flashes or a warm sensation all over the body
• Dry mouth
• Earache
• Feeling unwell like having a cold
• The body is weak, lethargic, and weak

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Drug Isosorbide Mononitrate Warnings and Cautions

What should be known before using isosorbide mononitrate?

Before using this drug, pay attention to the following:

• Tell your doctor or pharmacist if you have an allergy to isosorbide mononitrate, isosorbide dinitrate, nitroglycerin, or any other type of allergy.
• Tell your doctor or pharmacist if you have a medical history of low blood pressure (hypotension).
• Tell your doctor or pharmacist if you have early signs of a heart attack.
• Tell your doctor or pharmacist if you have congenital heart disease.
• Tell your doctor if you have kidney and liver problems.
• Tell your doctor if you are pregnant or breastfeeding.
• Tell your doctor if you have recently been taking certain medications regularly. Whether it's prescription drugs, non-prescription drugs, and herbal products.
• This medicine may make you dizzy. Therefore, do not drive, operate machinery, or engage in any activity that requires high alertness until the effects of the drug have completely worn off.
• This medicine should not be used carelessly. Keep out of reach of children.

Is isosorbide mononitrate safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication.

Isosorbide mononitrate is included in the pregnancy risk category C according to the Food and Drug Administration (FDA), which is equivalent to the Food and Drug Administration (BPOM) in Indonesia.

The following references the pregnancy risk categories according to the FDA:

• A = no risk
• B = no risk in some studies
• C = there may be some risks
• D = positive evidence of risk
• X = contraindicated
• N = unknown

There is not yet sufficient information about the safety of using this medicine during pregnancy and breastfeeding. Always consult your doctor to weigh the potential benefits and risks before using this medication.

Drug Interactions Isosorbide Mononitrate

What medicines may interact with isosorbide mononitrate?

Drug interactions can change the performance of your medications or increase the risk of side effects from mild to serious. Not all possible drug interactions are listed in this document.

Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Some drugs that have the potential to cause severe interactions with this drug include:

• Riociguat
• Sildenafil
• Tadalafil
• Vardenafil
• Avanafil

On the other hand, medications that can cause serious interactions with this drug include:

• Cabergoline
• Ergoloid mesylate
• Ergonovine
• Ergotamine
• Thereselibib
• Ivacaftor
• Methylergonovin

While drugs that can cause moderate (moderate) interactions with this drug are:

• Arginine
• Captopril
• Crofelemer
• Dabrafenib
• Dichlorphenamide
• Iloperidone
• Maraviroc
• Mitotane
• Nitroglycerin
• Tetracaine

Finally, drugs that have the potential to cause mild interactions include:

• Acetylcysteine

There may be many other drugs that can interact with this drug. So, be sure to tell your doctor about all the drugs you use. Even those that don't appear on the list already mentioned

Can food or alcohol interact with isosorbide mononitrate?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider

What health conditions may interact with isosorbide mononitrate?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

• Allergy to nitrates (eg, amyl nitrate, butyl nitrate) and nitrites
• Chronic anemia
• Closed angle galucoma
• Congestive heart failure
• Heart attack
• Acute myocardial infarction
• Hypertrophic cardiomyopathy
• Hypotension (low blood pressure)
• Hypovolemia (low blood count)
• Liver disease
• Kidney illness
• Hypothyroidism
• Hypothermia
• Pregnant and breastfeeding
• Malnutrition

Isosorbide Mononitrate overdose

What are the symptoms of an isosorbide mononitrate overdose?

Some of the typical signs and symptoms of an overdose of this drug that you should be aware of include:

• Severe headache
• High fever
• The heart is beating fast
• Dazed
• Severe nausea and vomiting

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the emergency medical services provider (119) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.