Janumet: functions, dosage, side effects, how to use

Use

What is the function of Janumet?

Janumet is a drug commonly used to help lower blood sugar in adults with type 2 diabetes.

Each tablet of this medication contains metformin and sitagliptin. Both are essential medicines for diabetes.

Metformin works by reducing the production of glucose (sugar) in the liver. That's not all. This drug also works by increasing insulin sensitivity and reducing glucose absorption by the intestines.

While sitagliptin is a hyperglycemic agent from the dipeptidyl peptidase-4 (DPP-4) inhibitor class. This drug works by regulating the levels of insulin your body produces after eating.

Although it can help control blood sugar, this drug should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis.

You cannot buy this drug carelessly. Because, this drug is only available with a doctor's prescription.

How do you use Janumet?

In order for this drug to provide maximum benefits, it is important to use it as directed. Here are some rules for using drugs that you need to understand carefully.

• This medicine should be taken after meals to reduce stomach upset.
• This medicine should not be crushed, crushed, or crushed. Swallow the tablet whole with a glass of water.
• In order not to forget, take your medicine at the same time every day.
• If at any time you forget to take this medicine and the next interval for consumption is still far away, it is advisable to do so as soon as you remember.
• Meanwhile, if the time lag is near, ignore it and don't try to double the dose.
• Do not add or reduce doses of medication without your doctor's knowledge. Taking medication that is not according to the rules can increase the risk of side effects.
• While taking this medication, you should reduce or even stop drinking alcohol altogether.

It is important to understand that take this medication exactly as your doctor prescribes. Follow all the instructions for using the medicine listed on the prescription label and read all medication guides or instruction sheets carefully. Don't hesitate to ask a doctor if you don't really understand how to use it.

In addition, seek medical attention immediately if your condition does not improve or your symptoms continue to get worse. The sooner it is treated, the easier the treatment will be.

How to save Janumet?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medication down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Dose

The following information cannot be used as a substitute for a doctor's prescription. You MUST consult your doctor or pharmacist before using Janumet.

What is the Janumet dosage for adults?

Dosage for patients who are not taking the drug metformin

50 mg sitagliptin / 500 mg metformin hydrochloride orally 2 times a day.

Increasing the dosage is done gradually to reduce the side effects of digestive disorders due to metformin.

Dosage for patients already treated with metformin

Sitagliptin dose 50 mg orally 2 times a day (total daily dose 100 mg).

For patients taking metformin 850 mg, the recommended dose is 50 mg sitagliptin / 1000 mg metformin hydrochloride orally 2 times a day.

In principle, the dosage of the drug for each person may be different. Doctors usually determine the appropriate drug dosage based on the patient's age, overall health condition, and their response to treatment.

Be sure to always consult a doctor before taking any type of medication. This is solely to ensure that you are taking the drug according to the recommended dosage.

What is the dosage of Janumet for children?

The dose has not been established in pediatric patients (younger than 18 years). This medicine may not be safe for your child. It is always important to understand the safety of drugs before using them. Please consult a doctor or pharmacist for more information.

In what form is Janumet available?

This drug is available in the following dosage forms and levels:

• Film coated tablet with a strength of 50mg sitagliptin / 500mg metformin
• Film coated tablet with a strength of 50mg sitagliptin / 1000mg metformin

Side effects

What are the possible side effects of Janumet?

Just like other drugs, this drug has the potential to cause side effects from mild to severe. Some of the side effects that may occur as a result of taking this drug include:

• Muscle ache
• Body aches
• Limp, lethargic, and weak
• Sleepy
• Numbness or tingling sensation in the arms and legs
• Cold arms and legs
• Shortness of breath even when doing only light activity
• Stomach ache
• Nausea
• Gag
• Dizzy

In some people, this drug can also cause side effects such as:

• Severe pain in the upper abdomen spreading to the back
• Your appetite has decreased dramatically
• The heart was beating very fast
• You urinate less than usual
• Severe skin reactions
• Fever

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

You should also see a doctor immediately if you experience a severe allergic reaction.

Precautions & Warnings

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What should I pay attention to before using Janumet?

Consult your doctor or pharmacist if:

• You are pregnant or breastfeeding. This is because, while you are pregnant or breastfeeding your baby, you should only use drugs recommended by your doctor.
• You are taking other medicines, including those that are available without a prescription, such as herbal medicines and their supplements.
• You have an allergy to the drug metformin, sitagliptin, or other diabetes medication.
• You have a history of chronic diseases such as heart disease, hypertension, stroke, and cancer.
• You will get an injection of a dye or contrast agent for the x-ray procedure.
• You have acidosis, which is the high level of acidity of the blood.
• You experience hypoxia, which is a lack of oxidants in the tissues.

It is also important to know that this drug has side effects of dizziness and drowsiness. That is why, avoid driving, operating machinery, or other activities that require high alertness until the effects of the drug are completely gone.

Is Janumet safe for pregnant and lactating women?

There is no adequate research on the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category B according to the US Food and Drug Administration (FDA), the equivalent of the Food and Drug Administration (BPOM) in Indonesia.

The following references the pregnancy risk categories according to the FDA:

• A = Not at risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated,
• N = Unknown

Always consult your doctor or midwife before using any medicine, if you are pregnant, breastfeeding, or planning a pregnancy.

Drug Interactions

What medicines should not be taken at the same time as Janumet?

Janumet may interact with other drugs you are currently taking, which can change how your medication works or increase your risk of serious side effects. To avoid drug interactions, you should keep a list of all the drugs you use (including prescription drugs, non-prescription drugs and herbal products) and tell your doctor and pharmacist.

For your safety, do not start, stop using, or change the dosage of any of the medicines listed below without your doctor's approval.

A number of drugs that are allegedly able to interact negatively with the drug Janumet include:

• Acetazolamide (Diamox)
• Cimetidine (Tagamet)
• Ranitidine (Zantac)
• Morphine (MS Contin, Kadian, Oramorph)
• Ranitidine (Zantac)
• Topiramate (Topamax)
• Trimethoprim (Proloprim
• Primsol
• Bactrim
• Cotrim, Septra)
• Vancomycin (Vancocin, Lyphocin)
• Glipizide (Glucotrol, Metaglip),
• Glimepiride (Amaryl Avandaryl, Duetact)
• Glyburide (DiaBeta, Micronase, Glucovance
• Heart or blood pressure medications such as amiloride (Midamor), digoxin (Lanoxin), furosemide (Lasix), nifedipine (Nifedical, Procardia), procainamide (Procan, Pronestyl, Procanbid), quinidine (Quin-G), triamterene (Dyrenium).

You may be more likely to have high blood sugar if you take metformin and sitagliptin with other drugs that can increase blood sugar, such as:

• Isoniazid
• Diuretics (water pills)
• Steroids (prednisone and others)
• Heart or blood pressure medications (Cartia, Cardizem, Covera, Isoptin, Verelan, and others)
• Niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others)
• Phenothiazines (Compazine and others)
• Thyroid drugs (Synthroid and others)
• Birth control pills and other hormones
• Seizure drugs (Dilantin and others)
• Diet pills or medicines to treat asthma, colds or allergies

There may be many other drugs that can interact negatively with this drug and have not been mentioned above.

Therefore, make sure you always tell your doctor about medicines that are being regularly taken lately. Whether it's prescription drugs, non-prescription drugs, to natural and herbal medicines. This simple information can help your doctor determine other drugs that are safer and suitable for your condition.

Are there foods and drinks that should not be consumed when using Janumet?

Janumet may interact with food or alcohol, which can change how medications work or increase the risk of serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this medication.

Are there any health conditions you should avoid Janumet?

Janumet may interact with your health condition. These interactions can worsen your health condition or change the way the drugs work.

It is important to always let your doctor and pharmacist know all your current health conditions. Especially if you:

• Have or have had inflammation of the pancreas (pancreatitis).
• Have kidney problems.
• Having liver problems.
• Have heart problems, including congestive heart failure.
• Are pregnant and breastfeeding.

Overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (119) or immediately to the nearest hospital emergency department.

It is important to carry a written list of all prescription and nonprescription medicines you use in case of an emergency.

What should I do if I forget to take / take medicine?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.