Metamizole: functions, dosage, side effects, how to use it

Functions & Usage

What is metamizole used for?

Metamizole is a drug commonly used to relieve pain, reduce fever, and reduce inflammation in the body. This drug has another name methamphycone and dipyrone.

This drug belongs to the class non-steroidal anti-inflammatory drugs or NSAIDs. The way it works is by inhibiting inflammation in the body, so that body temperature decreases and pain is reduced.

Usually, this medication is given to treat pain due to a tumor, pain after surgery, or other severe pain.

Metamizole is not used to treat minor pain (toothache, headache, menstrual pain).

What are the rules for using metamizole drugs?

Taking metamizole or methampyrone must follow the medication rules in the patient brochure or your doctor's instructions, including:

• Take this medication after meals. Swallow the drug directly with the help of plain water.
• Do not chew or crush the tablet as this can increase the side effects of the drug.
• Take this medicine at the same time every day so that the drug can work more effectively.
• Do not use this medication for more than the recommended dose, for less, or for longer than the recommended dosage.
• If your condition gets worse or shows no change, consult a doctor immediately.

How to store this drug?

Here are some of the ways to store the drug metamizole or methampirone:

• Store this medication at room temperature. Do not be in a place that is too cold or too hot.
• Keep this medication away from exposure to sunlight or direct light.
• Keep this medication out of reach of children and pets.
• Do not store this medication in the bathroom or other damp places.
• Do not also store this drug until it freezes in the freezer.
• Other brands of this drug may have different storage rules.
• Always pay attention to the drug storage rules listed on the packaging.

If you are no longer using this medicine or if the medicine has expired, discard this medicine immediately according to the procedure for disposing of the medicine.

One of them, do not mix this drug with household waste. Do not also throw this drug in drains such as toilets.

Ask the pharmacist or staff from the local waste disposal agency about the proper and safe way to dispose of drugs for environmental health.

Do not flush medication down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Talk to your pharmacist about how to safely dispose of your medicine.

Dose

The information provided is not a substitute for a doctor's prescription. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose for metamizole for adults?

According to European Medicines Agency , here are the recommended doses of metamizole or methampyrone for adults:

Tablet

Adults and ages 15 and over: 500 - 1,000 mg 4 times a day, 6-8 hours apart for each dose.

The maximum daily dose for metamizole tablets is 4,000 mg (4 mg).

Injection (injection)

Adults and ages 15 and over: 500 - 1000 mg 4 times a day, 6-8 hours apart for each dose.

The maximum daily dose of metamizole in injection form is 4,000 - 5,000 mg (4-5 mg).

What is the dose of metamizole for children?

It is not known the safety and effectiveness of this drug for children. The use of metamizole drugs for children must be under the supervision of a doctor.

In what dosages and preparations is this drug available?

Metamizole is available in the following dosages and forms:

Tablet

Metamizole sodium tablet form is available in sizes 250 or 500 mg. Tablets are packaged in the form of blisters, strips and plastic bottles.

Injection (injection)

Metamizole sodium in the form of an injectable injection is available in a size of 2 mL (content 500 mg / mL).

Precautions & Warnings

What should be considered before using metamizole drugs?

Before taking metamizole, pay attention to the following:

Certain drugs and diseases

Tell your doctor about any medications you are currently using, whether prescription, non-prescription, supplements, or herbal medicines. This is because several types of drugs may interact with metamizole sodium.

In addition, it is also important to inform your doctor about any diseases or other health conditions that you are currently suffering from. It is possible that this drug can trigger interactions with certain diseases or health conditions.

Allergy

Tell your doctor if you have a history of allergies to metamizole sodium or other NSAID medicines.

Is this drug safe for pregnant and lactating women?

Metamizole or methampyrone should not be taken during pregnancy, especially during the first 12 weeks and the last 12 weeks because of the risk of fetal damage.

Avoid breastfeeding while you are using metamizole. After you stop using the medicine, give it a break of at least 2 days before returning to breastfeeding.

There is no adequate research on the risks of using metamizole in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using metamizole.

Side effects

What are the possible side effects of metamizole?

Metamizole or methampyrone can cause the following side effects:

Indigestion

• Nausea
• Gag
• Diarrhea
• Pain and discomfort in the stomach

Nervous system disorders

• Drowsiness
• Nervous
• Headache
• Drunk

Kidney disorders

• Blood in urine, change in urine color

Allergic reactions

• Skin rash
• Itchy
• Swollen
• Shortness of breath
• Cold sweat and more

Not everyone experiences this side effect. There are side effects not listed above.

If you have your own concerns about side effects, consult your doctor or pharmacist.

Drug Interactions

What drugs can interfere with the drug metamizole?

Metamizole or methampyrone can interact with a drug that you are taking, which can change how the drug works or increase the risk of serious side effects.

To prevent interactions, it's best to keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

The following medicines may cause side effects:

• penicillin
• metformin
• glimepiride
• gliclazide
• glipizide
• warfarin
• heparin
• nadroparin
• prednisone
• methylprednisolone
• dexamethasone

Can certain foods and drinks interfere with metamizole drugs?

Certain drugs, including metamizole, should not be used while eating certain foods because drug-food interactions can occur.

Smoking tobacco or consuming alcohol with certain drugs can also cause interactions to occur.

Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

Avoid eating grapefruit or drinking red grapefruit juice while using the medicine unless your doctor allows it.

Grapefruit and grapefruit drugs can increase the risk of interactions. Consult your doctor and pharmacist for more info.

What health conditions can interfere with the performance of this drug?

Metamizole can interact with your health condition. These interactions can worsen health conditions or change how the drugs work.

It is very important to always let your doctor and healthcare provider know all about your current health condition, especially:

• Hypotonia
• Hypovolemia
• Dehydration
• Gastric ulcer
• Bronchial asthma
• Kidney disorders
• Alcohol dependence

Overdose

What to do in an emergency or overdose?

In case of an emergency department or signs of an overdose due to metamizole consumption, contact the local emergency services provider (119) or immediately to the nearest hospital emergency department.

What should I do if I forget to take medicine or forget to take medicine?

If you miss a dose, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical consultation, diagnosis or treatment.