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Nalmefene: functions, dosage, side effects, how to use it

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What Drug Nalmefene?

What is Nalmefene used for?

Nalmefene is a drug to reverse the effects of opioid medication, which is also called a narcotic. The effects of opioids include drowsiness, low blood pressure, and slow breathing.

Nelmefene is also used to treat narcotic overdose or other situations where the side effects of opioids can be dangerous.

Nalmefene is also used for other reasons not listed in this article.

How do you use the drug Nalmefene?

Nalmefene is given by injection through a needle that is directed directly into a vein or muscle. You will receive this injection in a hospital or emergency situation.

After treatment with nalmefene, you will be monitored to ensure that the treatment is effective and that you no longer have the effects of the opioids.

How to store Nalmefene?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Nalmefene dosage

What should be considered before using the drug Nalmefene?

Before using Nalmefene,

  • Tell your doctor that you have an allergy to Nalmefene or other medicines.
  • Tell your doctor and pharmacist about any medications you are currently taking, whether prescribed or not prescribed by your doctor, including vitamins.
  • Tell your doctor if you are pregnant, are planning to become pregnant or are breastfeeding. If you become pregnant while taking Nalmefene, contact your doctor.

Is Nalmefene safe for pregnant and breastfeeding women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category B. (A = No risk, B = No risk in some studies, C = Possible risk, D = There is positive evidence of risk, X = Contraindicated, N = unknown)

Nalmefene may leach into breast milk and can injure a nursing baby. Tell your doctor if you are breastfeeding.

Nalmefene side effects

What are the possible side effects of Nalmefene?

If you are addicted to narcotics or have used opioid drugs for a long time, you may experience uncomfortable symptoms when you receive nalmefene to reverse the effects of a narcotic overdose.

Get medical help right away if you experience symptoms of an allergic reaction: itching; difficulty breathing; swelling of the face, tongue, lips, or throat.

Tell your nurse right away if you experience any of these symptoms, some of which may indicate that you should receive an additional dose of nalmefene:

  • Great sleepiness
  • Weakness or shortness of breath
  • Chest pain or discomfort in the chest
  • Feeling about to pass out

Less serious side effects include:

  • Nausea, vomiting, stomach pain
  • Muscle or joint pain
  • Cheerful
  • Feeling nervous or depressed

Not everyone experiences this side effect. There are some side effects not listed above. If you have your own concerns about side effects, please consult your doctor or pharmacist.

Nalmefene Drug Warnings and Cautions

What medicines can interfere with the drug Nalmefene?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Can certain foods and drinks interfere with the drug Nalmefene?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interfere with the performance of the drug Nalmefene?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

  • History of drug addiction
  • Liver disease
  • Kidney disease
  • Heart disease (especially if you are taking heart medication)

Nalmefene Drug Interactions

The information provided is not a substitute for a doctor's prescription. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage for Nalmefene for adults?

Common Adult Dose for Reversing Opioid Sedation

Initial dose: 0.25 mcg / kg intravenously once as the starting dose, followed by an additional 0.25 mcg / kg dose at 2 to 5 minute intervals until the opioid reversal process is complete.

If there is no response after the cumulative dose of 1 mcg / kg registered, the additional dose will have no effect.

If there is a reason for opioid dependence, an initial dose of 0.1 mg / 70 kg IV should be registered. If, within 2 minutes, there is no reverse response, the recommended dosage should be continued.

If IV access is not available, give 1 mg intravenously or through a muscle.

What is the dosage of Nalmefene for children?

The dosage for children has not been determined. Consult your doctor for more information.

In what dosages and preparations is Nalmefene available?

Injection, Parenteral: 100 mcg / mL, 1 mg / mL.

What to do in an emergency or overdose?

Because nalmefene is given in moderation by a healthcare professional, it is unlikely that you will overdose on this drug.

What should I do if I forget to take medicine or forget to take medicine?

This medication is given in an emergency situation by a healthcare professional, so you will not miss a dose.

Hello Health Group does not provide medical consultation, diagnosis or treatment.

Nalmefene: functions, dosage, side effects, how to use it
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