Petrazole: functions, dosage, side effects, how to use

Functions & Uses

What is Petrazole used for?

Petrazole is an antifungal drug. This drug is effective for fighting and eradicating fungal infections in the skin, throat, mouth, lungs, toenails and hands.

Each capsule of this drug contains 100 grams of Itraconazole. Itraconazole is an azole class antifungal agent that has strong antifungal activity with a broad spectrum.

By taking this medicine, the growth and development of fungi in the body can be minimized or even stopped.

Antifungal drugs will not work to treat viral infections such as flu or colds. So, use this drug with caution and as directed. These drugs are only available by prescription.

How do you use Petrazole?

In order for the drug to work optimally, here are some rules for using the Petrazole drug that you need to pay close attention to.

• Take this medication exactly as directed by your doctor. Follow all the instructions for using the medicine listed on the prescription label and read all medication guides or instruction sheets carefully. Don't hesitate to ask a doctor if you don't really understand how to use it.
• This medicine can be taken after meals 1-2 times a day, depending on doctor's orders.
• The capsule form of the drug must be swallowed whole. So, avoid crushing, chewing, or opening this medication from its protective capsules.
• Take this medication 2 hours before or 1 hour after taking antacids. This is because antacids can reduce the absorption of these drugs in the body.
• This medicine can also be taken at the same time as colas if you have achlorhydria (too little stomach acid) or if you are regularly taking medicines that reduce stomach acid. Call it ranitidine and omeprazole. Sikakan asked directly to the doctor or pharmacist for clearer information.
• Use this medicine for the length of time prescribed by your doctor. Even if your symptoms have improved, do not stop treatment.
• This medicine should not be used interchangeably with other people. Even if the person has the same symptoms as you. Because, the dosage of drugs for each person may vary.
• So that you remember, take this medicine at the same time every day. You can also make a reminder on your cellphone or notebook if you have to take this medication in a certain cycle.
• Do not add or reduce doses of medication without your doctor's knowledge. Taking medication that is not according to the rules can increase the risk of side effects.
• Immediately seek medical attention if your condition does not improve or your symptoms continue to worsen. The sooner it is treated, the easier the treatment will be.

How to store Petrazole?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Dose

What is the dosage for Petrazole for adults?

• Systemic yeast infection: 100-200 mg orally once daily. The dose can also be increased to 200 mg orally twice a day if the infection is widespread.
• Oropharyngeal candidiasis: 100 mg per day orally for 15 days. In patients with AIDS or neutropenia the dose is increased to 200 mg orally for 15 days.
• Oral candidiasis: 200 mg per day orally 1-2 times daily for 1-2 weeks. For infections that are resistant to the drug fluconazole, the dose is 100-200 mg orally 2 times a day for 2-4 weeks.
• Oropharyngeal candidiasis: 100 mg once daily for 15 days. For people with AIDS or neutropenia, the dose is 200 mg once a day orally for 15 days.
• Vulvonaginal Candidiasis: 200 mg orally twice daily. The drug is given for 1 day.
• Fungal nail infection: 200 mg per day by mouth for 3 months.
• Tinea corporis and tinea cruris. 100 mg per day orally for 15 days, or 200 mg per day for 7 days.
• Tinea manuum and tinea pedis. 100 mg per day orally for a full month, or 200 mg orally twice a day for 7 days.

In principle, the dosage of the drug for each person may be different. Doctors usually determine the appropriate drug dosage based on the patient's age, overall health condition, and their response to treatment. Be sure to always consult a doctor before taking any type of medication. This is solely to ensure that you are taking the drug according to the recommended dosage.

What is the dosage of Petrazole for children?

There is no definite dosage requirement for children. This medicine can be dangerous for children. It is important to understand the safety of drugs before use. Consult your doctor or pharmacist for more information.

In what dosages and preparations is Petrazole available?

This drug is available in capsule form with a strength of 100 mg.

Side effects

What are the side effects of Petrazole?

The side effects most often complained of after taking this medicine include:

• Nausea and vomiting
• Sleepy
• Body feels weak
• Headache
• Dizzy
• Stomach ache
• Constipation
• Diarrhea
• A reddish rash appears on the skin
• Itching all over or part of the body
• Fever
• Unusual taste in mouth
• Hair loss
• Muscle pain or cramps
• Changes in menstrual periods

While side effects that are less common and need to be aware of include:

• Kliyengan seemed to want to pass out
• Blurred vision
• Ringing in ears
• Heart pounding
• Difficulty urinating
• Pain or burning sensation when urinating
• Decreased appetite
• Hypokalemia, low potassium levels
• Edema aka swelling all over or part of the body
• Pale stool color
• Jaundice
• Cold sweat often appears
• Dark urine
• Severe skin reactions

Not everyone experiences side effects when using this drug. There may also be some side effects not mentioned above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Precautions & Warnings

What should be known before using Petrazole?

There are several things you need to know before using this drug, including:

• Tell your doctor if you have a history of allergies to Itraconazole or other antifungal drugs.
• Tell your doctor if you have a history of liver and kidney disease.
• Tell your doctor if you have a history of chronic diseases including heart disease, stroke, diabetes, cancer, and so on.
• Tell your doctor if you have a history of cystic fibrosis or other lung problems.
• Tell your doctor if you have a history of a weak immune system due to certain diseases, such as HIV / AIDS.
• Tell your doctor if you have recently been taking certain medications regularly. Whether it's prescription drugs, non-prescription drugs, to herbal medicines.
• Tell your doctor if you plan to become pregnant, are pregnant, and are breastfeeding.
• This drug has side effects of dizziness and drowsiness. Therefore, avoid driving, operating machinery, or other activities that require high alertness until the effects of the drug are completely gone.
• Stop using this drug if you experience an allergic reaction. If left untreated, this drug can cause dangerous reactions that are fatal.

Is Petrazole safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA), the equivalent of the Food and Drug Administration (BPOM) in Indonesia.

The following references the pregnancy risk categories according to the FDA:

• A = Not at risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated,
• N = Unknown

Always consult your doctor or midwife before using any medicine, if you are pregnant, breastfeeding, or planning a pregnancy.

Drug Interactions

What medicines should not be taken with Petrazole?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Some drugs that have the potential to cause interactions with petrazole include:

• Itraconazole
• Nexium (esomeprazole)
• Omeprazole
• Prednisone
• Avanafil
• Cisapride
• Eliglustat
• Ranolazine
• Ticagrelor
• Irinotecan
• Isavuconazonium
• Methadone
• Naloxegol
• Lurasidone or pimozide (antipsychotic medication)
• Lomitapide, lovastatin, simvastatin (cholesterol-lowering drug)
• Dihydroergotamine, ergonovine, ergotamine, or methylergonovine (ergot drugs)
• Eplerenone, felodipine, ivabradine, or nisoldipine (heart or blood pressure medicine)
• Disopyramide, dofetilide, dronedarone, or quinidine (medicines for heart rhythm disorders)
• Midazolam or triazolam (sedative)

There may be many other drugs that can interact with this drug. So, be sure to tell your doctor about all the drugs you use. Even those that don't appear on the aforementioned list.

What foods and drinks should not be consumed while using Petrazole?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your doctor.

Are there certain health conditions you should avoid Petrazole?

The presence of other health problems in your body may affect the use of this drug. Some of the health problems that can interact with the drug Petrazole include:

• Hypersensitivity to the drug Itraconazole
• Are pregnant and planning to become pregnant
• Breastfeeding
• Kidney and liver disease
• Heart disease
• Cystic fibrosis or other lung problems
• Weak immune system

Overdose

What should I do in an emergency or overdose?

In an emergency or overdose situation, call 119 or take it to the nearest hospital immediately.

What should I do if I forget to take medicine or forget to take medicine?

If you miss a dose, take it as soon as you remember. However, if you just remember when it's time for the next dose, just ignore the missed dose, and continue taking it as scheduled. Do not use this medication in double doses.

Hello Health Group does not provide medical consultation, diagnosis or treatment.