Probucol: functions, dosage, side effects, how to use it

Functions & Usage

What is the drug Probucol used for?

Probucol is a drug to reduce cholesterol levels in the blood, which may help prevent medical disorders caused by cholesterol blocking blood vessels.

Probucol is only valid by prescription.

Probucol was withdrawn voluntarily from the market in the US during 1995 for safety reasons.

What are the rules for using the drug Probucol?

Many patients who have high cholesterol levels will not be aware of the signs of this problem. Many people may even feel normal.

Take this medication exactly as directed by your doctor, even if you may feel well. Try not to skip doses and don't take more of your medication than your doctor recommends.

Remember that probucol will not cure the condition but it does help control it. Therefore, you should continue taking this medicine as instructed if you expect your cholesterol levels to remain low.

Follow the special diet given by the doctor carefully. This is the most important part of controlling the condition, and it is important if the medication is working well. Probucol works better when taken with food.

Before prescribing medication for your condition, your doctor may try to control your condition by suggesting a special diet for you. It may be a diet low in fat, sugar, and / or cholesterol. Many people are able to control their condition by following their doctor's orders carefully for proper diet and exercise. Medication is only prescribed when additional help is needed and is only effective if a proper diet and exercise schedule is followed.

Also, probucol is less effective if you are extremely overweight. It may be important that you stick to a stricter diet. However, check with your doctor before undergoing any diet.

Make sure your healthcare professional knows if you are on a low sodium, sugar, or other special diet.

How do you store Probucol?

Store the medicine at room temperature away from light and moisture. Do not store in the bathroom and freeze medication. Medicines under different brands may have different storage methods. Check the product box for instructions on how to store it, or ask the pharmacist. Stay away from children and pets.

It is forbidden to flush the medicine in the toilet or throw it into the drain if not told to. Properly discard this product if it is past the deadline or is no longer needed. Consult a pharmacist or local waste disposal company for more in-depth details on how to safely dispose of the product.

Precautions & Warnings

What should be considered before using the drug Probucol?

Before using, first consider the benefits and risks. This is a decision that must be made after you discuss it with your doctor. For Probucol the following should be considered:

Allergy

Tell your doctor if you have had any unusual or allergic reactions to Probucol or any other medicines. Also, tell your healthcare professional if you have any other types of allergies, such as food, coloring, preservatives, or animals. For over-the-counter products, read labels or packaging materials carefully.

Pediatrician

There is no specific information on the benefits of probucol in children. However, use is not recommended in children younger than 2 years because cholesterol is needed for normal development.

Geriatric

Many drugs have not been studied, especially in the elderly. Hence, it may not be known whether the mode of action of the drugs is appropriate for the action of young adults or whether they cause different side effects or disorders in the elderly. There is no specific information comparing the benefits of probucol in the elderly with benefits in other age groups.

Is the drug Probucol safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This medication is a risk category B pregnancy (no risk in some studies).

Side effects

What are the possible side effects of Probucol?

Together with the required effects, the drugs may cause some unwanted effects. While not all of these side effects are possible, if they do occur they may need medical attention. Check with your doctor as soon as possible if the following side effects appear:

More general

• Dizziness or fainting
• Fast or irregular heartbeat

Rarely

• Swelling of the face, hands, or feet, or in the mouth
• Bleeding or bruising is not uncommon
• Tiredness or weakness is not uncommon

Several side effects may arise that usually do not require medical attention. These side effects may disappear during treatment as the body adjusts to the drug. In addition, your healthcare professional may be able to advise you on ways to prevent or reduce some of these side effects. Check with a healthcare professional if the following side effects persist or bother you or you have any questions:
More general

• Bloating
• Diarrhea
• Nausea and vomiting
• Stomach ache

Less often

• Headache
• Numbness or tingling in the fingers, toes, or face

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Drug Interactions

What drugs can interfere with the drug Probucol?

Using this medication with the following medicines is not recommended. Your doctor may decide not to treat you with this drug or change some of the drugs you take.

• Amifampridine
• Bepridil
• Cisapride
• Dronedarone
• Foscarnet
• Levomethadyl
• Mesoridazine
• Pimozide
• Piperaquine
• Sparfloxacin
• Terfenadine
• Thioridazine
• Ziprasidone

Using this medication with the medicines below is usually not recommended, but may be needed in some cases. If the two drugs are prescribed together, your doctor may change the dose or the length of time you take one or both drugs.

• Acecainide
• Ajmaline
• Amiodarone
• Amisulpride
• Anagrelide
• Aprindine
• Aripiprazole
• Arsenic Trioxide
• Astemizole
• Azimilide
• Bretylium
• Buserelin
• Chloral Hydrate
• Chloroquine
• Chlorpromazine
• Clarithromycin
• Crizotinib
• Dabrafenib
• Delamanid
• Deslorelin
• Disopyramide
• Dofetilide
• Dolasetron
• Domperidone
• Droperidol
• Enflurane
• Erythromycin
• Escitalopram
• Fingolimod
• Flecainide
• Fluconazole
• Fluoxetine
• Gemifloxacin
• Gonadorelin
• Goserelin
• Halofantrine
• Haloperidol
• Halothane
• Histrelin
• Hydroquinidine
• Ibutilide
• Isoflurane
• Isradipine
• Ivabradine
• Ketoconazole
• Leuprolide
• Lidoflazine
• Lorcainide
• Mefloquine
• Metronidazole
• Moxifloxacin
• Nafarelin
• Octreotide
• Ondansetron
• Pasireotide
• Pazopanib
• Pentamidine
• Pirmenol
• Prajmaline
• Procainamide
• Prochlorperazine
• Propafenone
• Quetiapine
• Quinidine
• Risperidone
• Sematilide
• Sertindole
• Sevoflurane
• Sotalol
• Spiramycin
• Sulfamethoxazole
• Sultopride
• Tedisamil
• Telithromycin
• Trifluoperazine
• Trimethoprim
• Triptorelin
• Vandetanib
• Vasopressin
• Vemurafenib
• Vinflunine
• Zolmitriptan
• Zotepine

Using this medication with any of the following medicines may increase your risk of side effects, but using both drugs may be the best treatment for you. If the two drugs are prescribed together, your doctor may change the dose or the length of time you take one or both drugs.

• Cyclosporine

Can certain foods and drinks interfere with the drug Probucol?

Certain drugs cannot be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss with a healthcare professional about using drugs with food, alcohol, or tobacco.

What health conditions could interfere with the performance of the drug Probucol?

The presence of other medical disorders may affect the use of this drug. Make sure you tell your doctor if you have any other medical problems, especially:

• Gallbladder or gallstone disease or
• Heart disease - Probucol might make this condition worse.
• Liver disease - higher levels of probucol in the blood are possible, which may increase the chance of side effects.

Dose

The information provided is not a substitute for a doctor's prescription. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of the drug Probucol for adults?

For oral dosage form (tablet): 500 mg 2 times a day taken at breakfast and at dinner.

What is the dosage of the drug Probucol for children?

For oral dosage form (tablets):

• Up to 2 years - use is not recommended.
• 2 years and older - the dose must be determined by a doctor.

In what dosages and preparations is Probucol available?

Tablet

What to do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (118/119) or immediately to the nearest hospital emergency department.

What should I do if I forget to take medicine or forget to take medicine?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical consultation, diagnosis or treatment.