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Spiramycin: functions, dosage, side effects, how to use

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What Drug Spiramycin?

What is spiramycin for?

Spiramycin or spiramycin is a drug with a function to treat various kinds of bacterial infections. This drug belongs to the class of antibiotic drugs, especially the macrolide type.

Spiramycin is often used to treat toxoplasmosis infections in pregnant women. According to Drugs.com, this drug is safer for pregnancy than other antibiotic drugs, such as pyrimethamine or sulfadiazine. There have never been reports of cases of abnormalities or disorders in pregnancy after pregnant women take spiramycin antibiotics.

This drug can also be used for other bacterial and parasitic infections, especially those classified as gram-positive and negative bacteria such as:

  • Streptococcus pyogene (causes of sore throat, tonsillitis, cellulitis, rheumatic fever)
  • Staphylococcus aureus (causes of upper respiratory tract infection)
  • Corynebacterium diphtheriae (causes of diphtheria)
  • Neisseria meningitidis (causes of meningitis)
  • Bordetella pertussis (causes whooping cough)
  • Campylobacter (one of the causes of food poisoning and diarrhea)

Because spiramycin is an antibiotic, it cannot be used to treat colds, flu, or other illnesses caused by viral infections.

This drug is available under various trademarks, one of which is Rovadin.

How is spiramycin used?

Spiramycin is a drug that is available in oral and injectable forms. This medicine is best used before meals.

To completely cure the bacterial infection, continue using this medication until it wears off even though you feel better before the drug runs out. If you stop using antibiotics too soon, the infection may recur.

This medicine works best if the drug levels in the body are always in the same amount. This means that it is recommended that you take spiramycin at the same time.

Medicines in the form of tablets, capsules, caplets, or pills should not be crushed or crushed. This is because destroying the drug without the doctor's instructions can affect the performance of the drug itself.

If you really have trouble swallowing the drug without crushing it first, consult this with your doctor. Your doctor may be able to prescribe other drug options, such as liquid drugs or tablets that can be dissolved in water. For injection drugs, follow the rules of use given by the doctor and medical team.

Do not use this medication for more than the recommended dose, for less, or for longer than the recommended dosage. If your condition gets worse or shows no change, consult a doctor immediately.

How to store this drug?

Spiramycin is best stored at room temperature, which is between 15 and 30 degrees Celsius. Avoid storing this medicine in a humid place or in direct sunlight.

Do not store this medication in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush otilonium bromide down the toilet or down the drain unless instructed to do so. Discard this product when the drug has expired or when it is no longer needed.

Consult your pharmacist or local waste disposal agency about how to safely dispose of your medicine.

Spiramycin dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the spiramycin dosage for adults?

The following is the spiramycin dosage for adults:

  • Oral (tablets, capsules, syrup): 1-2 grams 2 times a day, or 500 mg - 1 gram 3 times a day
  • Injection: 500 mg every 8 hours

What is the dose of spiramycin for children?

The dosage is based on the child's weight. The dose given is generally 25 mg per kg of the child's body weight, 2 times a day.

In what dosage and form is this drug available?

The drug spiramycin is available in various shapes and sizes, namely:

  • Tablets (125 mg, 250 mg, and 500 mg)
  • Capsules (750,000 IU and 1,500,000 IU)
  • Syrup (100 ml Rovadin brand, per 5 ml contains 125 mg spiramycin)
  • Injection

Spiramycin side effects

What side effects can be experienced due to spiramycin?

Digestive problems, nausea, vomiting, diarrhea, or stomach pain may occur. If the side effects of these drugs persist or become more troublesome, contact your doctor.

If you experience a severe (anaphylactic) allergic reaction to this medicine, seek medical attention immediately. Symptoms of an allergic reaction can include:

  • itchy rash
  • difficulty breathing
  • swelling of the face, lips, tongue, or throat.

Not everyone experiences the above side effects. There may be some side effects not listed above.

If you have concerns about certain side effects, consult your doctor or pharmacist.

Drug Warnings and Cautions for Spiramycin

What should be known before using spiramycin?

Each medicine has its own warnings and risks that you should be aware of before using it. Here are some of the things you need to pay attention to when using spiramycin:

Certain drugs and diseases

Tell your doctor about any medications you are currently using, whether prescription, non-prescription, supplements, or herbal medicines. This is because several types of drugs may interact with spiramycin.

In addition, it is also important to inform your doctor about any diseases or other health conditions that you are currently suffering from. It is possible that this drug can trigger interactions with certain diseases or health conditions.

Allergy

Tell your doctor if you have a history of allergies to certain drugs, especially spiramycin or any other ingredients in this medicine. Also, get checked to see if you have any other allergies, for example to certain foods, dyes, or animals.

Children

The performance and safety of this drug in children is unknown. The exact dosage for children has not been established.

However, there may be some conditions that allow your child to use this medicine, and this of course can only be done based on doctor's instructions.

Therefore, make sure you consult your doctor before giving this drug to your child.

Elderly

There are still many drugs that have not been studied for safety and performance in older people, including spiramycin. It is possible that these drugs work differently, or have different side effects in the elderly.

Before giving this drug to the elderly, first consult a doctor.

Is this drug safe for pregnant and lactating women?

There is no adequate research on the risks of using the drug spiramycin in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication.

This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA). The following references the pregnancy risk categories according to the FDA:

  • A = Not at risk
  • B = No risk in several studies
  • C = May be risky
  • D = There is positive evidence of risk
  • X = Contraindicated
  • N = Unknown

Drug Interactions of Spiramycin

What medicines may interact with spiramycin?

Although certain drugs are not recommended to be used together, in other cases two different drugs can be used together even though drug interactions may occur.

In these cases, your doctor may change the dose, or other precautions need to be taken. Tell your doctor if you are using any other prescription or nonprescription drugs.

Increased risk ventricular arrhythmias at concomitant use with astemizole, cisapride, and terbenadine. Risk of acute dystonia with concomitant use of fluphenazine.

Can food or alcohol interact with spiramycin?

Certain drugs should not be used when eating certain foods because drug-food interactions can occur.

Smoking tobacco or consuming alcohol with certain drugs can also cause interactions to occur.

Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with spiramycin?

The presence of other health problems can affect the use of this drug. Tell your doctor if you have other health problems, especially:

  • liver disorders
  • history of arrhythmias
  • blockage or obstruction of the bile ducts

Spiramycin overdose

What should I do in an emergency or overdose?

In case of an emergency or signs of an overdose, contact the emergency services provider (118 or 119) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose, use this medication as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Make sure you don't double your dose in one shot.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Spiramycin: functions, dosage, side effects, how to use
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