Suxamethonium chloride: functions, dosage, side effects, how to use

What Drug Suxamethonium Chloride?

What is Suxamethonium Chloride used for?

Suxamethonium Chloride is a drug to be injected in the following conditions:

• To relax muscles during surgery in adults and children
• To help insert a tube down the throat (endotracheal intubation), if a person needs help breathing
• To reduce the strength of your muscle contractions if you have severe spasms

The active ingredient Suxamethonium Chloride is a drug that relaxes the muscles of the body.

How do you use the drug Suxamethonium Chloride?

Suxamethonium Chloride injection will be given to you as an injection into your vein (intravenously) and / or into a muscle (intramuscular). Dosage depends on your individual needs, body weight, amount of muscle relaxation required and how the medication is given.

How to store Suxamethonium Chloride?

Store in room or refrigerator with a temperature of 2 ° C-8 ° C, do not freeze. Keep away from light and moisture. Don't keep it in the bathroom. Other brands of this drug can have different storage rules. Pay attention to the storage instructions on the packaging of your product, or ask your pharmacist. Keep all medicines away from children and pets. Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Suxamethonium Chloride dosage

What should be considered before using the drug Suxamethonium Chloride?

You should not be given Suxametonium Chloride Injection if you:

• Allergy to Suxamethonium Chloride or any of the other ingredients listed in chapter 6 of this leaflet
• Have been told by a doctor that you have abnormal cholinesterase activity
• A member of your family has previously reacted badly to anesthetic that causes a very high body temperature (malignant hyperthermia)
• Has had a major accident, surgery or serious burns in the last three months
• Not being able to move for a long time such as allowing a broken bone to repair or rest long term
• Have high levels of potassium in the blood (hyperkalemia).
• Recently had an eye injury
• Suffering from a problem caused by putting too much pressure on your eyes which is called 'glaucoma'
• Or someone in your family has a muscle or nerve disease, such as muscle disease, paralysis, motor neuron disease, muscular dystrophy or cerebral palsy.

Is Suxamethonium Chloride safe for pregnant and lactating women?

There is no adequate research on the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This medicine is included in the pregnancy risk category C. (A = No risk, B = No risk in some studies, C = Possible risk, D = There is positive evidence of risk, X = Contraindicated, N = unknown)

Suxamethonium Chloride side effects

What are the possible side effects of Suxamethonium Chloride?

Like all medicines, Suxamethonium Chloride injection can cause side effects, although not everyone will get it.

Allergic reactions are very rare (this drug affects less than 1 in 10,000 people)

If you experience an allergic reaction, tell the doctor or nurse right away. Signs may include:

• Sudden wheezing, chest pain, chest tightness
• Swelling of the eyelids, face, lips, mouth or tongue
• Thickened skin rash or "hives" anywhere on your body
• Collapsed, fell off balance

Very common side effects (affect 1 in 10 people)

• Cramps or pain in the stomach and a feeling of nausea or a feeling of having a stomach (full stomach)
• The muscles under the skin appear to twitch
• Excessive production of saliva
• Muscle pain after surgery - the doctor will monitor your condition for things like this

General (affects less than 1 in 10 people)

• Fluid pressure in the eye that can cause headaches or blurred vision
• Speed ​​up or slow down your heart rate
• Reddish skin
• Skin rash
• High levels of potassium in the blood
• High blood pressure / low blood pressure
• Protein in the blood or urine due to muscle damage
• Muscle damage that can make your muscles sore or feel tender, stiff and weak, your urine may also look dark or red or have a cola-colored color.

Rarely (affects less than 1 in 1000 people)

• Abnormal heart rhythm
• Heart problems include changes in the way your heart works where it beats or the heart stops beating
• Temporary difficulty breathing or being unable to breathe
• Difficulty opening your mouth

Very rare (affects less than 1 in 10,000 people)

• High body temperature

If any of the above side effects become more serious

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Suxamethonium Chloride Drug Warnings and Cautions

What medicines can interfere with the drug Suxamethonium Chloride?

Although some drugs should not be taken at the same time, in other cases some drugs can also be used together even though interactions may occur. In cases like this, the doctor may change the dose, or take other necessary precautions. Tell your doctor if you are taking any other over-the-counter or prescription drugs.

Can certain foods and drinks interfere with the action of the drug Suxamethonium Chloride?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interfere with the performance of the drug Suxamethonium Chloride?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

• Tetanus
• Tuberculosis (TB) or other severe, long-term infection
• An illness that you have been suffering from for a long time, which makes your body feel weak
• Cancer
• Anemia
• Malnutrition (lack of nutrition)
• Liver or kidney problems
• Auto immune diseases, such as multiple sclerosis
• An underactive thyroid gland known as Myxoedema
• Muscle disease eg Myaesthenia Gravis
• Blood transfusion or heart bypass
• Insecticide
• An allergic reaction to any muscle relaxant given as part of surgery

Special care will be taken when this medicine is given to children and the elderly (elderly).

Drug Interactions of Suxamethonium Chloride

The information provided is not a substitute for a doctor's prescription. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage of Suxamethonium Chloride for adults?

Adults and parents (seniors) and children over 12 years:

By intravenous injection:

1 mg per kilogram of body weight.

An additional dose of about 50-100% of the initial dose given at 5-10 minute intervals will maintain muscle relaxation.

A maximum of 500mg / hr will be given.

By slow intravenous infusion (drip):

0.1-0.2% solution, 2.5-4mg per minute to a maximum of 500mg per hour.

What is the dosage of the drug Suxamethonium Chloride for children?

Children 12 years and under:

By intravenous injection (Children 1-12 years):

1mg per kilogram of body weight up to a maximum of 150mg

Infants (under 1 year):

2 mg per kilogram of body weight up to a maximum of 150mg

By intramuscular injection (Children 1-12 years):

up to 4 mg per kilogram of body weight up to a maximum of 150mg

Infants (under 1 year):

up to 4-5mg per kilogram of body weight to a maximum of 150mg

In what dosages and preparations is Suxamethonium Chloride available?

Injection of 20 mg / mL (10 mL); 100 mg / mL

What to do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (118/119) or immediately to the nearest hospital emergency department.

What should I do if I forget to take medicine or forget to take medicine?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical consultation, diagnosis or treatment.