Trihexyphenidyl: functions, dosage, side effects, how to use

What medicine is Trihexyphenidyl?

What is Trihexyphenidyl for?

Trihexyphenidyl is a drug to treat the symptoms of Parkinson's disease or other uncontrolled movements caused by the side effects of certain psychiatric drugs (antipsychotics such as chlorpromazine / haloperidol).

This medication also helps reduce muscle stiffness, excessive sweating, and saliva production. Not only that, trihex is also able to help improve walking ability in Parkinson's patients.

Trihexyphenidyl belongs to a class of anticlonergic drugs that work by blocking certain natural substances (acetylcholine).

The drug trihexyphenidyl cannot help with the out-of-control movement problems that are caused by tardive dyskinesia. In fact, these drugs can make the condition worse.

What are the rules for taking Trihexyphenidyl?

Follow the rules given by your doctor or pharmacist before starting treatment with trihexyphenidyl. If you have any questions, consult your doctor or pharmacist.

Trihexyphenidyl is taken usually 3-4 times a day after meals and at bedtime, or as directed by a doctor.

Your doctor may give you a low dose to start with, and increase the dose gradually to get the right dose for you.

The dosage is based on your medical condition, age, and your body's response to therapy.

If you are using the liquid form of the drug trihexyphenidyl, measure your dose with a measuring spoon or measuring device. Do not use a home tablespoon as the dosage may not be correct.

Take medication regularly to get maximum results. To help you remember, drink it at the same time each day.

Take trihexyphenidyl at least 1 hour before antacids containing magnesium, aluminum, or calcium.

Allow at least 1-2 hours between doses of trihexyphenidyl and certain diarrhea medications (adsorbent antidiarrheals such as kaolin, pectin, attapulgite).

Take trihexyphenidyl medication at least 2 hours after ketoconazole. Antacids and some diarrhea medications can prevent trihexyphenidyl from being fully absorbed, and these products can prevent ketoconazole from being fully absorbed when these products are taken together.

If you are taking trihexyphenidyl to treat the side effects of another medicine, your doctor may instruct you to take it regularly on schedule or only when needed.

If you are taking the drug trihexyphenidyl for Parkinson's disease, your doctor may change the dose of your other medicine (for example, levodopa). Follow the doctor's instructions.

There is a small chance that trihexyphenidyl can be addictive. Do not increase your dose, increase your amount of medication, or take it for longer than recommended.

Stop using the drug completely when instructed. Even so, some conditions may become worse when treatment is stopped suddenly. That is why, you may need to decrease the dosage slowly.

When used for an additional period of time, this drug may not work well and may require a different dosage. Talk to your doctor if the trihexyphenidyl medication stops working. Tell your doctor if your condition remains the same or gets worse.

How is Trihexyphenidyl stored?

Trihexyphenidyl is best stored at room temperature, away from direct light and damp places.

Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules.

Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed.

Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Trihexyphenidyl dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage of Trihexyphenidyl for adults?

Trihexyphenidyl dosage for extrapyramidal symptoms in adults:

The initial dose is 1 mg once a day, can be increased to 5-15 mg per day in 3-4 divided doses.

Trihexyphenidyl dosage for Parkinson's disease:

• Initial dose: 1 mg / day; the dose may be increased by 2 mg in 3-5 day intervals
• Maximum dose: 6-10 mg / day in 3-4 separate doses

What is the dosage of Trihexyphenidyl for children?

The dosage for children has not been determined. Consult your doctor and pharmacist.

In what dosage is Trihexyphenidyl available?

• 2 mg tablet; 5 mg
• Elixir 2 mg / 5 ml

Trihexyphenidyl side effects

What side effects can be experienced due to Trihexyphenidyl?

The common side effects of trihexyphenidyl are:

• Dry mouth
• Big eyes or blurred vision
• Tired or dizzy
• Difficulty urinating or constipation
• Nervousness or anxiety
• Stomach upset
• Less sweat

If you experience any of the serious side effects below, stop using trihexyphenidyl and seek medical help or contact your doctor right away:

• Severe allergic reaction (difficulty breathing; closing of throat; swelling of the lips, tongue, or face; or freckles)
• Fever
• Fast or irregular heartbeat
• Anxiety, hallucinations, confusion, restlessness, hyperactivity, or loss of consciousness
• Convulsions
• The eye hurts
• Skin rash

Not everyone experiences the following side effects. There may be some side effects not listed above.

If you have concerns about certain side effects, consult your doctor or pharmacist.

Trihexyphenidyl Drug Warnings and Cautions

What should be known before using trihex?

Before using this drug, there are several things that need attention. These things will usually take into account the amount of benefits obtained.

Some things that doctors usually consider when deciding to give trihex, include:

Allergy

Tell your doctor if you have any allergies to this drug or any other medications. It will be his consideration for prescribing this drug or using other drugs.

Also tell any allergies you have, such as to food, coloring, preservatives, or animals. For over-the-counter products, read the labels or ingredients on the packaging carefully.

Children

No information is available regarding the relationship between age and the effect of trihexyphenidyl in the pediatric population. Safety and success have not been proven.

Elderly

No information is available regarding the relationship between age and the effect of trihexyphenidyl in elderly patients.

Even so, older men tend to have prostate problems as they age, and older people tend to have age-related problems with kidney, liver, or heart conditions.

This condition requires attention or an adjustment in the dose of trihexyphenidyl for elderly patients.

Is Trihexyphenidyl safe for pregnant and lactating women?

Pregnancy and breastfeeding: there is insufficient information regarding the safety of using trihexyphenidyl during pregnancy and breastfeeding.

Always consult your doctor and let him know your condition, especially if you are pregnant and breastfeeding.

Trihexyphenidyl Drug Interactions

What medicines may interact with Trihexyphenidyl?

Drug interactions can change the performance of the trihexyphenidyl drug or increase the risk of serious side effects. Not all possible drug interactions are listed in this document.

Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medicine without your doctor's approval.

Although several drugs should not be used simultaneously, in some cases the two drugs that have a risk of interaction may be prescribed together. If this is the case, the doctor will adjust the dose given or the schedule for taking the drug to prevent adverse drug interactions.

Also inform your doctor if you are using other prescription or nonprescription drugs.

Using the drug trihexyphenidyl with potassium not recommended. Your doctor may decide not to treat you with trihexyphenidyl or change some of the drugs you have used.

Using this medication with any of the following drugs is usually not recommended, but may be needed in some cases.

• Morphine
• Morphine Sulfate Liposome
• Oxymorphone
• Umeclidinium

Taking the above medicines together with trihex can increase the risk of certain side effects. Even so, this option will be taken with various adjustments by the doctor if it is considered the most appropriate treatment.

If both drugs are prescribed together, your doctor may change the dose or how often you use one or both drugs.

• Betel Nut
• Chlorpromazine
• Haloperidol
• Perphenazine

Can food or alcohol interact with trihex?

Certain drugs should not be used when eating or consuming certain foods because drug interactions can occur.

Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions may interact with Trihexyphenidyl?

Any other health problem in your body can affect the use of the drug trihexyphenidyl. Tell your doctor if you have other health problems, in particular:

• Blockage of the stomach or intestines
• Enlarged prostate
• Glaucoma
• Hypertension (high blood pressure)
• Urinary blockage — Use with caution. Can make conditions worse
• Kidney illness
• Liver disease — Use with caution. The effect will increase due to the slowly leaving the drug in the body

Trihexyphenidyl overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of the drug trihexyphenidyl, take it as soon as you remember. If you are close to taking the next medication, ignore the missed dose. Continue taking the medication according to the original schedule. Do not double your dose on a one-time schedule.