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Dopamine (dopamine): functions, dosage, side effects, how to use

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Anonim

Dopamine (Dopamine) What Medicine?

What is dopamine used for?

Dopamine is a form of medicine from substances or substances that naturally exist in the body. Dopamine is a liquid that can be injected into the body through a vein.

This drug belongs to the class of prescription drugs, so you can only use this drug if it was prescribed by your doctor and you cannot buy it at a pharmacy freely.

Dopamine works by increasing the strength of the heart pumping and blood flow to the kidneys. Primarily, this drug is used to treat conditions that arise when you go into shock.

Usually, this condition is experienced when there is a heart attack, trauma, surgery, heart failure, kidney failure, and various other serious health conditions.

This indicates that the use of dopamine has the potential to neutralize blood pressure, blood flow to vital organs, and improve liver function in patients with shock disorders.

Dopamine may also be used for situations not described in this article.

How is dopamine used?

Here are some things that should be considered and done when you are using dopamine, namely:

  • Dopamine is injected into a vein through a vein access (IV line). You will be given the injection at a clinic or hospital.
  • Tell your doctor or nurse if you feel a burning sensation, pain, or swelling around the injection site.
  • Breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be closely monitored while you are receiving dopamine injections.
  • To make sure dopamine is helping your condition and isn't having any harmful effects, your blood cells and kidney function may need to be checked frequently. Don't skip the control schedule to check your blood or urine.
  • Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

How is dopamine stored?

As with most drug storage methods, this drug is best stored at room temperature and kept away from direct light exposure. Also put this drug away from damp places.

Do not store this medication in the bathroom and do not freeze it in the freezer. Other brands of this drug may have different storage rules.

Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed.

Consult your pharmacist or local waste disposal agency about how to safely dispose of your product.

Dopamine (Dopamine) Dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dopamine dosage for adults?

Adult dosage for thoracoplastics

  • Initial dose: 2-10 micrograms (mcg) / kilogram (kg) / minute by continuous IV infusion
  • Maintenance dose: 2-50 mcg / kg / minute by continuous IV infusion

Adult dosage for congestive renal failure

  • Initial dose: 2-10 mcg / kg / minute by continuous IV infusion
  • Maintenance dose: 2-50 mcg / kg / minute by continuous IV infusion

Adult dose for myocardial infarction

  • Initial dose: 2-10 mcg / kg / minute by continuous IV infusion
  • Maintenance dose: 2-50 mcg / kg / minute by continuous IV infusion

Adult dosage for chronic renal failure

  • Initial dose: 2-10 mcg / kg / minute by continuous IV infusion
  • Maintenance dose: 2-50 mcg / kg / minute by continuous IV infusion

Adult dose for shock

  • Initial dose: 2-10 mcg / kg / minute by continuous IV infusion
  • Maintenance dose: 2-50 mcg / kg / minute by continuous IV infusion

Adult dosage for sepsis

  • Initial dose: 2-10 mcg / kg / minute by continuous IV infusion
  • Maintenance dose: 2-50 mcg / kg / minute by continuous IV infusion

What is the dose of dopamine for children?

Children's dosage for thoracoplastics

  • Initial dose: 2-10 mcg / kg / minute by continuous IV infusion
  • Maintenance dose: 2-50 mcg / kg / minute by continuous IV infusion

Children's dosage for congestive heart failure

  • Initial dose: 2-10 mcg / kg / minute by continuous IV infusion
  • Maintenance dose: 2-50 mcg / kg / minute by continuous IV infusion

Children's dosage for myocardial infarction

  • Initial dose: 2-10 mcg / kg / minute by continuous IV infusion
  • Maintenance dose: 2-50 mcg / kg / minute by continuous IV infusion

Children's dosage for chronic renal failure

  • Initial dose: 2-10 mcg / kg / minute by continuous IV infusion
  • Maintenance dose: 2-50 mcg / kg / minute by continuous IV infusion

Child dosage for shock

  • Initial dose: 2-10 mcg / kg / minute by continuous IV infusion
  • Maintenance dose: 2-50 mcg / kg / minute by continuous IV infusion

Children's dosage for sepsis

  • Initial dose: 2-10 mcg / kg / minute by continuous IV infusion
  • Maintenance dose: 2-50 mcg / kg / minute by continuous IV infusion

In what dosage is dopamine available?

Dopamine is available in the following dosages.

Solution, Intravenous, with hydrochloride:

Generic: 0.8 mg / mL (250 mL, 500 mL); 1.6 mg / mL (250 mL, 500 mL); 3.2 mg / mL (250 mL); 40 mg / mL (5 mL, 10 mL); 80 mg / mL (5 mL); 160 mg / mL (5 mL).

Dopamine (Dopamine) side effects

What side effects can be experienced due to dopamine?

Dopamine side effects may include irregular heartbeat, onset, anxiety, and shortness of breath. Seek emergency medical help right away if you develop signs of an allergic reaction: Hives, difficulty breathing; swelling of the face, lips, tongue, or throat.

Not only that, the side effects of using dopamine drugs that may occur include:

  • chest pain
  • fast, slow, or pounding heart rate
  • pain or difficulty urinating, bloody urine
  • weakness, confusion, swollen feet or ankles, infrequent or no urination
  • breath feels weak
  • feel like you might pass out, even when you are lying down
  • a burning, painful, or swollen sensation around the injection site
  • feeling cold, numb, or your hands or feet appear blue
  • the skin of the hands or feet darkens or changes.

Tell your doctor or nurse immediately if you experience any of the side effects mentioned above.

The side effects that are less severe but possible include:

  • headache
  • feeling anxious
  • nauseous vomit
  • chills, goosebumps

You need to know that the doctor prescribes this drug to you after weighing the risks and benefits of using the drug to treat your health condition.

Not everyone experiences the side effects mentioned above. There may be some side effects not listed above. If you have concerns about certain side effects you feel after using dopamine, consult your doctor or pharmacist.

Dopamine (Dopamine) Drug Warnings and Cautions

What should be known before using dopamine?

There are several things you should know and do before you decide to use dopamine, including:

  • Tell your doctor if you have pheochromocytoma or a rare tumor of the adrenal glands. You should not receive dopamine injections if you have this condition.
  • If possible, tell your doctor if you have diseases such as heart rhythm problems, blockage of the arteries in the heart, asthma, diabetes, Raynaud's syndrome, and Buerger's disease.
  • Tell your doctor if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the past 21 days..
  • Tell your doctor if you have any allergies to other medicines, foods, preservatives, or dyes.
  • If you are pregnant, make sure your obstetrician knows how this medicine is given to you. Because in times of emergency, it may be difficult for you to tell your doctor if you are pregnant.
  • Always follow the guidelines given to you regarding medication use.

Is dopamine safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA).

The following references the pregnancy risk categories according to the FDA:

  • A = No risk,
  • B = not at risk in several studies,
  • C = May be risky,
  • D = There is positive evidence of risk,
  • X = Contraindicated,
  • N = Unknown

Meanwhile, in nursing mothers, the use of this drug has the potential to reduce the amount of production of breast milk (ASI), so if this medicine must be used, make sure that the benefits of its use outweigh the risks that the mother and her baby may get. As much as possible, first discuss the use of this drug with your doctor.

Dopamine (Dopamine) Drug Interactions

What other medicines may interact with dopamine?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Although certain drugs cannot be used together, in other cases 2 different drugs can be used simultaneously although drug interactions may occur. In this case, the doctor can change the dose, or other warnings may be needed. While you are using this medicine it is very important for your doctor to know if you are taking any of the drugs mentioned below. The following interactions were selected based on differences in drug potential and not necessarily all included.

Using this drug with other drugs is usually not recommended, but may be needed in some cases. If the two drugs are prescribed together, your doctor may have changed the dose or frequency of use of one or both drugs.

There are 188 types of drugs that can interact with dopamine. Some of them are as follows.

  • droperidol (Inapsine)
  • epinephrine (EpiPen, Adrenaclick, Twinject, and others)
  • haloperidol (Haldol)
  • midodrine (ProAmatine)
  • phenytoin (dilantin)
  • vasopressin (Pitressin)
  • diuretic (water pill)
  • antidepressants such as amitriptyline (Elavil, Vanatrip, Limbitrol), doxepin (Sinequan, Silenor), nortriptyline (Pamelor), and others
  • beta blockers such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Dutoprol, Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others -other
  • cough or cold medicines that contain antihistamines or decongestants
  • ergot medications such as ergotamine (Ergomar, Cafergot, Migergot), dihydroergotamine (D.H.E. 45, Migranal), ergonovine (Ergotrate), or methylergonovine (Methergine)
  • phenothiazines such as chlorpromazine (Thorazine), fluphenazine (Permitil, Prolixin), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), promethazine (Pentazine, Phenergan, Anergan, Antinaus), thioridazine (Mellarelazine), or

Can food or alcohol interact with dopamine?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with dopamine?

Not only drugs and food, dopamine drug use can also interact with various health problems. The presence of other health problems in your body may affect the use of this drug. Tell your doctor immediately if you have other health problems, namely:

  • coronary artery disease, which is a disease related to the blood vessels in the heart.
  • circulation problems such as Raynaud's syndrome, which is a condition that results from reduced blood flow to certain parts of the body.
  • history of blood clots
  • diabetes
  • dehydration
  • Buergers' disease, which is a blood vessel disease that primarily affects the limbs of the body.
  • asthma
  • arrhythmias, which are symptoms if you have problems with your heart rate or rhythm.
  • Peripheral artery disease, which is a condition in which blood vessels become narrowed, reducing blood flow to the legs.
  • pheochromocytoma, a rare tumor found in the adrenal glands

Dopamine (Dopamine) overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department. However, the drug that must be given by a medical professional should not cause an overdose because they have understood the correct dosage for your condition.

What should I do if I miss a dose?

The use of this drug must be given by a medical professional and cannot be used independently by you. That way, it is almost impossible if you miss a dose from using this drug because the medical professional who will inject it into you will certainly remind you. However, if you and a medical professional both forget, make an appointment to see a doctor or nurse so that you don't miss the dose of medication.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Dopamine (dopamine): functions, dosage, side effects, how to use
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