Hepatitis B immunoglobulin: functions, dosage, side effects, how to use

Hepatitis B Immunoglobulin What Drugs?

What is hepatitis B immunoglobulin for?

Hepatitis B immunoglobulin is generally used to prevent people from contracting hepatitis B after receiving a liver transplant, and in babies born to mothers infected with hepatitis B. It can also be used on people who have been infected with hepatitis B through blood-related products, having sexual contact with an infected person, or living in the same house as an infected person.

Hepatitis B immunoglobulin is not a vaccine, because it cannot provide long-term protection from hepatitis B. For long-term protection, you should receive a hepatitis B vaccine such as Engerix-B, Recombivax HB, or Twinrix. Hepatitis B immunoglobulin may also be used for purposes not listed in this medication guide.

How is the hepatitis B immunoglobulin used?

Hepatitis B immunoglobulin is injected into a muscle or vein through an infusion pump. A health professional will administer this injection.

For prevention after exposure to contaminated blood :

Hepatitis B immunoglobulin is usually given immediately upon exposure to an infected person, preferably within 7 days. Boosters are usually given 24 hours later. Your doctor may also recommend that you receive the Hepatitis B vaccine when you start therapy with the Hepatitis B immunoglobulin

For prevention after sexual contact with an infected person:

Hepatitis B immunoglobulin is given in a single dose within 14 days after last contact. You must also receive the hepatitis B vaccine if you want to continue in contact with the person.

For the prevention of people living in the same house with an infected person:

This medicine should be given to children under 12 months of age, nurses who have had contact with the blood of an infected person, and people who share razors, toothbrushes, or other personal items with an infected person. Family members may also need the hepatitis B vaccine.

For babies born to mothers infected with hepatitis B:

This medicine is usually given within 12 hours of birth, or when the baby has become medically stable. In addition to hepatitis immunoglobulin, the baby should also receive the hepatitis B vaccine, which is given as a series of 3 shots.

The first hepatitis B vaccine shot is usually given when a child is 7 days old. Vaccinations are then given 1 month and 6 months after the first hepatitis B vaccine. If the baby does not receive the vaccine before 3 months of age, a second dose of Hepatitis B immunoglobulin should be given. Your child's vaccination schedule may also differ from the guidelines above. Follow your doctor's instructions or the schedule recommended by the health department in your area of ​​residence.

If the baby is not getting the hepatitis B vaccine at all, the second and third doses of hepatitis immuno globulin should be given 3 and 6 months after the first dose. When using Hepatitis B immunoglobulin, you may need periodic blood tests. This treatment can have an unusual effect on certain blood sugar tests.

How is the hepatitis B immunoglobulin stored?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Hepatitis B Immunoglobulin Dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the hepatitis B immunoglobulin dosage for adults?

Follow the dosage that has been determined by the doctor or according to what is written on the medicine package.

What is the dose of hepatitis B immunoglobulin for children?

Follow the dosage that has been determined by the doctor or according to what is written on the medicine package.

In what dosage is hepatitis b immunoglobulin available?

This drug is available in the following dosages:

HepaGam B
- Injections> 312 units / mL

HyperHEP B S / D
- Injection of 220 units / mL

Prophet-HB
- Injections> 312 units / mL

Hepatitis B Immunoglobulin side effects

What side effects can be experienced due to hepatitis b immunoglobulin?

Seek immediate medical help if you experience any of the following signs of an allergic reaction: hives, difficulty breathing, swelling of the face, lips, tongue, or throat.

Call your doctor immediately if you experience:

• fever, dry mouth, red or swollen gums
• lightheaded, like you wanted to pass out
• liver problems, pain in the upper abdomen, loss of appetite, blackened urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
• symptoms of fluid accumulating in the lungs (pain in the chest, pain when breathing in, fast heartbeat, feeling dizzy or short of breath especially when lying down
• symptoms of blood clots or stroke - sudden numbness or weakness (especially in one part of the body), chest pain, difficulty breathing, fast heartbeat, coughing up blood or pain, swelling, warmth, or redness in the hands or feet

Other side effects include:

• nausea, vomiting, diarrhea, stomach pain
• chills, memory problems, heat stroke, vision problems
• flu symptoms such as stuffy nose, sneezing, sore throat
• mild rash or
• pain, redness, bruising, or softening of the part of the body where the medicine is injected

Hepatitis B Immunoglobulin Caution and Warnings

What should be known before using hepatitis b immunoglobulin?

You should not receive hepatitis B immune globulin if you are allergic to it.

Hepatitis B immunoglobulin may increase your risk of developing blood clots, especially if you have:

• heart disease, coronary artery disease (hardened blood vessels), history of blood clots
• risk of causes of coronary artery disease (such as menopause, smoking, being overweight, have high blood pressure, high cholesterol, have a family history of coronary artery disease, or you are an elderly person)
• if you need blood thinners
• if you are taking birth control pills or hormone modifiers
• if you are using a urinary aid
• if you are bedridden or weak
• allergic to human immunoglobulins
• bleeding or irregular blood clots such as hemophilia or
• diabetes

Is hepatitis b immunoglobulin safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA).

The following references the pregnancy risk categories according to the FDA:

• A = No risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated,
• N = Unknown

There is not yet sufficient information about the safety of using this medicine during pregnancy and breastfeeding. Always consult your doctor to weigh the potential benefits and risks before using this medication.

Hepatitis B Immunoglobulin Drug Interactions

What drugs may interact with hepatitis b immunoglobulin?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Can food or alcohol interact with hepatitis B immunoglobulin?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with hepatitis B immunoglobulin?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

• allergy (severe) to human globulins, or a history thereof
• immunoglobulin (IgA) deficiency — never given to patients with this disease
• atherosclerosis (hardening of the blood vessels), or a history of it
• blood clotting problems, or a history
• diabetes
• have heart or blood vessel disease
• hyperviscosity (thick blood), contracted or diagnosed
• long-term paralysis — use with care or as it can cause more severe side effects
• blood clotting
• thrombocytopenia (low number of platelets) —do not be given to patients who have been exposed to prophylaxis unless the benefits outweigh the disadvantages.

Hepatitis B Immunoglobulin overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.