Lacidipine: functions, dosage, side effects, how to use

What Drug Lacidipine?

What is Lacidipine for?

Lacidipine functions to slow the movement of calcium through muscle cells in the walls of blood vessels. Lacidipine works by blocking calcium channels in these muscle cells. Calcium is needed by muscle cells to contract. By slowing down calcium intake, lacidipine exerts a relaxing effect on muscles.

Lacidipine acts specifically on muscle cells in the artery walls to relax muscles. This causes the arteries in the body to relax.
The process of relaxation and widening of the small arteries in the body will reduce the resistance of the heart muscle when it pumps blood around the body, thereby reducing blood pressure. In conclusion, lacidipine acts as a blood pressure-lowering drug.

How do I use lacidipine?

Take the medicine by mouth, once a day in the morning. Use this medication according to doctor's instructions.

Take this medicine regularly to get optimal benefits. To help you remember, take this medication at the same time every day, unless directed by your doctor to say otherwise.
Certain medical conditions may require different rules of use as directed by your doctor.

How is lacidipine stored?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.
Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Lacidipine dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of lacidipine for adults?

Oral

Hypertension

2 mg once a day in the morning; increase to 4 mg daily, as needed. In some patients, the dose increase can be up to 6 mg / day

What is the dosage of lacidipine for children?

There is no provision for the dosage of this drug for children. This medicine can be dangerous for children. It is important to understand the safety of drugs before use. Consult your doctor or pharmacist for more information.

In what dosage is lacidipine available?

Tablet, oral: 2 mg, 4 mg

Lacidipine side effects

What side effects can I experience due to lacidipine?

Side effects include:

• a sensation of burning and flushing on the body (flushing)
• palpitations (awareness of the heartbeat)
• headache
• dizzy
• chest pain (angina)
• muscle cramp
• skin rash
• ankle swelling
• ulcer
• unwell
• more urine volume than usual
• lethargic
• changes detected during a blood test, related to the liver
• swelling of the gums
• mood changes
• low blood pressure

If any of the above conditions arise, or get worse, contact your doctor.

Tell your doctor right away if you experience: chest pain (or getting worse), pulse weakness, shortness of breath and gasping, low blood pressure, cold and clammy skin, blue lips or you feel dizzy or want to faint, weakness, or general pain.

Remember that your doctor prescribes this medication to you after considering all factors, including the benefits that outweigh the risk of possible side effects. Not everyone experiences the above side effects.

Serious allergic reactions are very rare, but seek immediate medical attention if these side effects occur: hives, difficulty breathing, swelling of the face, lips, tongue, or throat.
Not everyone experiences the above side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Lacidipine Drug Warnings and Cautions

What should be known before using lacidipine?

Before using this medication, tell your doctor if:

• You are allergic to calcium-channel blockers (dihydropyridines), such as nifedipine, amlodipine
• You have angina that gets worse, both in duration and frequency (unstable angina)
• You have aortic stenosis, which is a narrowing of the main artery of the heart where blood is pumped out to the rest of the body
• You have had a heart attack, or a history of it for several months
• You have heart failure to maintain adequate blood circulation (cardiogenic shock)
• You have porphyriasis (an inherited blood disease)
• You have a rare disorder of galactose intolerance, Lapp's lactose deficiency, or glucose-galactose malabsorption (lacidipine tablets contain lactose)

This medicine is not recommended for children.

Is lacidipine safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using lacidipne in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication.

Isoconazole is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA)

The following references the pregnancy risk categories according to the FDA:

• A = Not at risk
• B = No risk in several studies
• C = May be risky
• D = There is positive evidence of risk
• X = Contraindicated
• N = Unknown

Lacidipine Drug Interactions

What medicines may interact with lacidipine?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

• ACE inhibitors, for example aldesleukin
• alpha-blockers, for example alprostadil
• angiotensin II receptor antagonists, eg losartan
• antipsychotics
• benzodiazepines, eg temazepam, diazepam
• baclofen
• beta-blockers, for example propranolol
• calcium-channel blockers, eg verapamil, nifedipine
• clonidine
• diazoxide
• diuretics, eg furosemide, bendroflumethiazide
• dopamine agonists, eg bromocriptine, apomorphine
• hydralazine
• levodopa
• MAOI antidepressants, for example phenelzine
• methyldopa
• minoxidil
• moxisylyte
• moxonidine
• nicorandil
• nitrates, for example glyceryl trinitrate
• tizanidine

The drugs below can increase the breakdown of lacidipine in the liver, which will reduce the effectiveness of the drug. If you are taking any of the following drugs together with lacidipine, your doctor will increase your dose of lacidipine:

• carbamazapine
• phenobarbital
• phenytoin
• primidone
• rifampicin
• St. John's wart

The drugs below can slow the breakdown of lacidipine in the liver, which increases the risk of side effects. If you are taking any of the drugs below along with lacidipine and experience lightheadedness or other side effects, contact your doctor. Your doctor will reduce your dose of lacidipine:

• cimetidine
• clarithromycin
• erythromycin
• itraconazole
• ketoconazole
• protease inhibitors for HIV infection (ritonavir, nelfinavir, saquinavir)
• telithromycin

The following medicines may reduce the blood pressure-lowering effect of this medicine:

• corticosteroids (dexamethasone or prednisolone)
• estrogen, such as those contained in birth control pills
• routine use of non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, diclofenac or indomethacin (small doses of painkillers will have no significant effect)

Can food or alcohol interact with lacidipine?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with lacidipine?

Any other health conditions you have can affect using lacidipine. Always tell your doctor if you have other health problems, especially:

• decreased liver function
• problems with the heart's electromagnetic path
• medical history of weak heart or heart failure, especially of the left ventricular

Lacidipine overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, use it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.