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Nebivolol: functions, dosage, side effects, how to use

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What Drug Nebivolol?

What is nebivolol for?

Nebivolol is used to treat high blood pressure. Reducing high blood pressure can help prevent strokes, heart attacks, and kidney problems.

This drug belongs to a class of drugs called beta blockers . This drug works by blocking the action of natural substances in the body such as epinephrine on the heart and blood vessels. This effect can reduce heart rate, blood pressure, and heart spasms.

OTHER USES: This section deals with uses for drugs that are not listed on professional labels, but may be prescribed by your doctor. Use this medication for the conditions below if your doctor has prescribed it.

This medicine can prevent chest pain (angina), heart failure, and increase safety after a heart attack.

How is nebivolol used?

Take this medication as directed by your doctor, usually once a day with or without food. The dosage will be given according to your medical condition and response to treatment.

Use this remedy regularly for optimal results. To remind you, you can take this medication at the same time every day.

It may take several weeks before you experience the optimal benefits of this medication. It is very important to keep taking this drug even if you feel better. Generally, people with high blood pressure don't feel sick.

Tell your doctor if your condition does not improve or gets worse (for example, if your regular blood pressure checks remain the same or increase).

How is nebivolol stored?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Nebivolol dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage for nebivolol for adults?

Adult dosage for high blood pressure:

Initial dose: take 5 mg once a day.

Maintenance dose: take 40 mg once daily, titrated to patient response and tolerance.

The dose can be increased after 2 weeks.

What is the dose of nebivolol for children?

The safety and effectiveness of the drug has not been announced by pediatricians. Consult a doctor for more information.

In what dosage is nebivolol available?

Tablets: 2.5 mg, 5 mg. 10 mg, 20 mg.

Nebivolol side effects

What side effects can be experienced due to nebivolol?

Serious side effects generally don't occur. Stop using Nebivolol and contact a doctor if an allergic reaction occurs (hives, difficulty breathing, closure of the throat, swelling of the lips, face, or tongue).

Call your doctor if you have serious side effects such as:

  • difficulty breathing, although not active
  • swelling of the ankles or feet
  • slow or unstable heart rate
  • numbness or coldness in the feet and hands

Less serious side effects include:

  • dizzy
  • feels tired
  • nausea, stomach pain
  • diarrhea
  • insomnia (insomnia)

Not everyone experiences the following side effects. There may be some unspecified side effects. If you have concerns about certain side effects, consult your doctor or pharmacist.

Nebivolol Drug Warnings and Cautions

What should be known before using nebivolol?

Before using nebivolol, tell your doctor or pharmacist if you are allergic to nebivolol, acebutolol (Sectral), atenolol (Tenormin, for Tenoretic), betaxolol (Kerlone), bisoprolol (Zebeta, to Ziac), carvedilol (Coreg), labetalol (Trandate)), metoprolol (Lopressor, Toprol XL), nadolol (Corgard, on Corzide), pindolol, propranolol (Inderal, InnoPran XL, on Inderide), sotalol (Betapace, Betapace AF, Sorine), timolol (Blocadren, on Timolide), drugs other components, or any other composition contained in the nebivolol tablet. Ask your pharmacist about the composition of nebivolol.

Tell your doctor and pharmacist about the prescription and nonprescription drugs, vitamins, supplements, and herbal products you are currently using. Be sure to mention: amiodarone (Cordarone, Pacerone); beta blockers such as acebutolol (Sectral), atenolol (Tenormin, in Tenoretic), betaxolol (Kerlone), bisoprolol (Zebeta, pda Ziac), carvedilol (Coreg), labetalol (Trandate), metoprolol (Lopressor, Toprol XL), nadolol (Corgard, on Corzide), pindolol, propranolol (Inderal, InnoPran XL, on Inderide), sotalol (Betapace, Betapace AF, Sorine), timolol (Blocadren, on Timolide); bupropion (Wellbutrin); calcium channel blockers such as diltiazem (Cardizem, Dilacor, Tiazac, etc.) and verapamil (Calan, Isoptin, Verelan); chlorpheniramine (antihistamine in allergy and cold medicines); cimetidine (Tagamet); clomipramine (Anafranil); clonidine (Catapres); digoxin (Digitek, Lanoxicaps, Lanoxin); disopyramide (Norpace); duloxetine (Cymbalta); fluoxetine (Prozac, Sarafem); haloperidol (Haldol); insulin; oral medications for diabetes; methadone (Dolophine, Methadose); paroxetine (Paxil); propafenone (Rythmol); quinidine (Quinaglute, Quinidex); reserpine; ritonavir (Norvir, in Kaletra); and sildenafil (Revatio, Viagra). Your doctor may change the dose of your medication or watch your possible side effects more carefully.

Tell your doctor if you have a slow heart rate or liver problems or heart failure. Your doctor may forbid you to use nebivolol.

Tell your doctor if you have asthma or other lung disease, diabetes, hyperthyroidism, circulation problems, kidney disease, allergies, or pheochromocytoma (a tumor that is near the kidney and can cause high blood pressure and speed up the heart rate).

Tell your doctor if you are pregnant or planning a pregnancy, or are breastfeeding. If you become pregnant while using nebivolol, call your doctor.

If you are having surgery, including dental surgery, tell your doctor if you are taking nebivolol.

You should know that nebivolol might cause drowsiness. Do not drive or use machinery until you know what effect the drug is on you.

You should know that if you experience symptoms of allergies to a different substance, your reaction may worsen when you take nebivolol and your allergic reaction may not respond to the usual dose of epinephrine.

Is nebivolol safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medicine. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA).

The following references the pregnancy risk categories according to the FDA:

  • A = No risk,
  • B = not at risk in several studies,
  • C = May be risky,
  • D = There is positive evidence of risk,
  • X = Contraindicated,
  • N = Unknown

It is not known whether nebivolol passes to breast milk or injures a nursing baby. Do not use this medication without telling your doctor if you are breastfeeding.

Nebivolol Drug Interactions

What medicines may interact with nebivolol?

Drug interactions can change how medications work or increase the risk of serious side effects. This document does not contain all the drugs that can interact. Make a list of all the products you use (including prescription / nonprescription drugs and herbal medicines) and tell your doctor and pharmacist. Do not start, stop, or change the dose without your doctor's approval.

  • cimetidine (Tagamet)
  • clonidine (Catapres)
  • digitalis (digoxin, Lanoxin)
  • isoniazid (for treating tuberculosis)
  • methimazole (Tapazole)
  • reserpine
  • ropinirole (Requip)
  • ticlopidine (Ticlid)
  • beta-blockers others such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Dutoprol, Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others
  • antibiotics such as terbinafine (Lamisil)
  • antidepressants such as clomipramine (Anafranil), desipramine (Norpramin), duloxetine (Cymbalta), fluoxetine (Prozac, Rapiflux, Sarafem, Selfemra, Symbyax), imipramine (Tofranil), paroxetine (Paxil, Pexeva), sertraline Parnate)
  • anti-malarial drugs such as chloroquine (Aralen) or pyrimethamine (Daraprim), or quinine (Qualaquin)
  • heart or high blood pressure medications such as amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta, Amturnide), clonidine (Catapres, Clorpres, Kapvay, Nexiclon), diltiazem (Cardizem, Cartia, Dilacor, Diltia, Diltzac, Taztia, Tiazac), nicardipine (Cardene), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan, Tarka), etc.
  • heart rate medications such as amiodarone (Cordarone, Pacerone), quinidine (Quin-G), procainamide (Pronestyl), disopyramide (Norpace), flecaininde (Tambocor), mexiletine (Mexitil), propafenone, (Rythmol), etc.
  • HIV or AIDS drugs such as delavirdine (Rescriptor) or ritonavir (Norvir, Kaletra)
  • drugs to treat psychiatric disorders, such as aripiprazole (Abilify), chlorpromazine (Thorazine), clozapine (Clozaril, FazaClo), fluphenazine (Permitil, Prolixin), haloperidol (Haldol), perphenazine (Trilafon), or thioridazine (Mellarilaf)

Can food or alcohol interact with nebivolol?

Certain drugs should not be used with meals or at certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with nebivolol?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

  • angina (chest pain) - can make the chest hurt if it stops too quickly
  • peripheral vascular disease (closure of blood vessels) —use with caution; can make matters worse
  • bradycardia (slow heart rate)
  • cardiogenic shock (shock after a heart attack)
  • heart block
  • heart failure
  • liver disease
  • lung diseases (eg, bronchitis, emphysema)
  • sick-sinus syndrome (Heart rate problems), Without sedation, should not be used in patients with these conditions
  • diabetes
  • hyperthyroidism (overactive thyroid)
  • hypoglycemia (low blood sugar) - can mask the symptoms and signs of this disease, such as a fast heartbeat
  • Kidney illness
  • liver disease, severe - use with caution. The effect may be increased due to the slow depletion of the drug in the body
  • pheochromocytoma (adrenal tumor) —Use medications alpha-blockers before using this drug

Nebivolol overdose

What should I do in an emergency or overdose?

In case of emergency or overdose, contact your local emergency services provider (112) or immediately to the nearest hospital emergency department.

Symptoms of an overdose include:

  • slow heart rate
  • dizziness or fainting
  • feeling shaky
  • sweating
  • feeling confused
  • tense, disturbed, or sudden mood swings
  • dizzy
  • numbness or a tingling feeling around the mouth
  • feeling of weakness
  • pale skin
  • suddenly hungry
  • jerky movements
  • difficulty breathing
  • relapse
  • tired
  • gag

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Nebivolol: functions, dosage, side effects, how to use
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