Reserpine: functions, dosage, side effects, how to use it

What Drug Reserpine?

What is reserpine for?

Reserpine is a drug used with or without other drugs to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It works by reducing certain substances in the body (such as norepinephrine). This relaxes the blood vessels so that blood can flow more easily and also slows down the heart rate. This effect helps to lower blood pressure.

How do I use reserpine?

Take this medication by mouth with or without food, usually 1 to 2 times a day or as directed by your doctor.

Dosage is based on your medical condition and response to treatment. Do not increase your dose or take this drug more often than prescribed. This can increase the risk of serious side effects.

Use this remedy regularly for optimal benefits. You need to remember to take this drug at the same time every day.

It may take several weeks before you get the full benefits of this drug. This medicine should be taken continuously even if your condition has improved. Most people with high blood pressure don't feel sick.

Tell your doctor if your condition does not improve or if it gets worse (for example, blood pressure remains high or rises).

How do I save a reserpine?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Reserpine Dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of reserpine for adults?

Normal Dosage for Adults with Hypertension

Starting dose: 0.5 mg orally once a day for 1 to 2 weeks.

Maintenance dose: 0.1-0.25 mg orally once a day.

Normal Dosage for Adults with Schizophrenia

Starting dose: 0.5 mg orally once a day, but may range from 0.1 to 1 mg.

Maintenance dose: Adjust dosage (decrease or increase dose) according to patient response

Normal Dosage for Adults with Hyperthyroidism

The consumption of Reserpine levels during a thyrotoxic crisis is unknown.

Data are limited where seven patients with thyrotoxic crisis received Reserpine 1 to 5 mg intramuscularly, then 0.07-0.3 mg per kg in the first 24 hours revealed a significant increase in symptom-related dose within four to eight hours of drug administration.

What is the dose of reserpine for children?

Safety and effectiveness in pediatric patients (less than 18 years) have not been determined.

In what dosage is reserpine available?

Tablets, ready to drink: 0.1 mg; 0.25 mg

Reserpine side effects

What side effects can be experienced due to reserpine?

Drowsiness, dizziness, fatigue, nausea, vomiting, diarrhea, slow heart rate, and nasal congestion may occur. If you continue to experience any of these effects or they tend to get worse, tell your doctor or pharmacist right away.

Remember that your doctor has prescribed this medicine because he or she has judged that the benefit to you outweighs the risk of side effects. Many people using this drug do not get serious side effects.

Tell your doctor right away if any of these very rare side effects occur, such as: severe stomach pain, black stools, fainting, severe dizziness, shortness of breath, swelling of the feet or ankles, sudden unusual weight gain, breasts enlarged (in men), enlarged breasts (in women).

Tell your doctor right away if any of the rare but very serious side effects occur: very slow / fast / irregular heartbeat, unusual bleeding / bruising, unusual / uncontrollable movements (such as tremors), muscle stiffness.

This drug has caused depression. Depression can last for several months after stopping the drug. Tell your doctor right away if you experience signs of depression, including mental / mood changes (such as persistent / severe sadness, suicidal thoughts), trouble sleeping, loss of appetite, decreased sexual ability.

Very serious allergic reactions to this drug are rare. However, get medical attention right away if you notice any of the symptoms of a serious allergic reaction, including: rash, itching / swelling (especially face / tongue / throat), severe dizziness, trouble breathing.

Not everyone experiences this side effect. There may be some side effects not listed above. If you have any concerns about side effects, please consult a doctor or pharmacist.

Reserpine Drug Warnings and Cautions

What should be known before using reserpine?

Before using certain drugs, consider the risks and benefits first. This is a decision you and your doctor will have to make. For this drug, pay attention to the following:

Allergy

Tell your doctor if you have any unusual or allergic reactions to this or any other medicine. Also tell your doctor if you have any other types of allergies such as to food, coloring, preservatives, or animal allergies. For over-the-counter products, read the labels on the packaging carefully

Children

Although there is no specific information regarding the comparison of use of this drug in children with use in other age groups, it is not expected to cause any different side effects or problems in children than it does in adults.

Elderly

Many drugs have not been specifically studied for their efficacy in the elderly. Therefore, it may not be known whether the drug works in the same way as in adults. Although there is no specific information comparing the use of reserpine, hydralazine, and combined hydrochlorothiazide in the elderly with use in other age groups, it is not expected that this drug causes different side effects or problems in the elderly than in adults. However, drowsiness, dizziness, or fainting, or symptoms of too much potassium loss are more likely in the elderly, who are usually more sensitive to the effects of this drug. Also, this drug can reduce tolerance to cold temperatures in elderly patients.

Is reserpine safe for pregnant and lactating women?

There is not yet sufficient information about the safety of using this medicine during pregnancy and breastfeeding. Always consult your doctor to weigh the potential benefits and risks before using this medication.

Reserpine Drug Interactions

What medicines may interact with reserpine?

Using this medication with any of the following medicines is not recommended. Your doctor may decide not to recommend that you take this drug or change some of the other drugs you are taking.

• Brofaromine
• Clorgyline
• Dofetilide
• Furazolidone
• Iproniazid
• Isocarboxazid
• Lazabemide
• Linezolid
• Moclobemid
• Nialamide

• Pargyline
• Phenelzine
• Procarbazine
• Rasagiline
• Selegilin
• Tetrabenazine
• Toloxatone
• Tranylcypromine

Using this medication with any of the following medicines is not usually recommended, but may be necessary in some cases. If the two drugs are prescribed together, your doctor may change the dose or how often you use one or both drugs.

• Acetyldigoxin
• Arsenic trioxide
• Colchicine
• Cyclophosphamide
• Deslanoside
• Digitalis
• digitoxin
• Digoxin
• Droperidol
• Flecainid
• Fosphenytoin
• Iobenguane I am 123
• Ketanserin
• Levomethadyl
• Lithium
• Methotrexate
• Metildigoxin
• Ouabain
• Phenytoin
• Proscillaridin
• Sotalol

Using this medication with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If the two drugs are prescribed together, your doctor may change the dose or how often you use one or both drugs.

• Aceclofenac
• Acemetacin
• Alacepril
• Amtolmetin Guacil
• Aspirin
• Benazepril
• Bepridil
• Bromfenac
• Bufeksamak
• Captopril
• Carbamazepine
• Celecoxib
• Chlorpropamide
• Cholestyramine
• Choline Salicylate
• Cilazapril
• Clonixin
• Delapril
• Dexibuprofen
• Dexketoprofen
• Diclofenac
• diflunisal
• dipyrone
• Enalaprilat
• Enalapril maleate
• Etodolac
• Etofenamate
• Etoricoxib
• Felbinac
• Fenoprofen
• Fepradinol
• Feprazone
• Floctafenine
• Flufenamic acid
• Flurbiprofen
• Fosinopril
• Ginkgo
• Glipizide
• Gossip
• Ibuprofen
• Ibuprofen Lysine
• Imidapril
• Indomethacin
• Ketoprofen
• Ketorolac
• Licorice
• Lisinopril
• Lornoxicam
• Loxoprofen
• Lumiracoxib
• Meclofenamate
• Mefenamic acid
• Meloxicam
• Moexipril
• Morniflumate
• nabumeton
• Naproxen
• Nepafenac
• Niflumic Acid
• Nimesulide
• Oxaprozin
• Oxyphenbutazone
• Parecoxib
• Pentopril
• Lerindopril
• Phenylbutazone
• Piketoprofen
• Piroxicam
• Pranoprofen
• Proglumetacin
• Propyphenazone
• Proquazone
• Quinapril
• Ramipril
• Rofecoxib
• Salicylic acid
• Salsalat
• Sodium Salicylate
• Spirapril
• Sulindac
• Temocapril
• Tenoxicam
• Periprofenic acid
• Tolfenamic Acid
• Tolmetin
• Topiramate
• Trandolapril
• Valdecoxib
• Yohimbine
• Zofenopril

Can food or alcohol interact with reserpine?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with reserpine?

The presence of other medical problems may affect the use of this drug. Make sure you tell your doctor if you have any other medical problems, especially:

• allergies or other breathing problems such as asthma - Reserpine can cause breathing problems
• Type 2 diabetes mellitus - Hydrochlorothiazide can change the amount of diabetes medication needed
• epilepsy
• gallstones
• stomach ulcers
• Ulcerative colitis - Reserpine increases stomach activity, which can make the condition worse
• gout (history) - Hydrochlorothiazide can increase the amount of uric acid in the blood, which can cause gout
• heart disease - Reserpine can cause heart rhythm problems or slow heart rate. Lowering blood pressure can make several conditions worse
• some kidney disease in patients which may not be treated properly when blood pressure is lowered by this medicine. The effect of Hydralazine may increase due to slower neutralization of the drug. If kidney disease is severe, Hydrochlorothiazide may not work
• liver disease - if Hydrochlorothiazide causes too much water loss from the body, liver disease can get much worse
• lupus erythematosus (history) - Hydrochlorothiazide can make the condition worse
• mental depression (or history) - Reserpine causes mental depression
• pancreatitis (inflammation of the pancreas)
• Parkinson's disease - Reserpine can cause effects like Parkinson's symptoms
• phaeochromocytoma
• stroke (recent) - lowering blood pressure can make the problems resulting from this condition worse

Reserpine overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.