Dienestrol: functions, dosage, side effects, how to use

Functions & Usage

What is Dienestrol used for?

Dienestrol is a drug that contains the hormone estrogen, usually used to treat atrophic vaginitis, an inflammation that makes the vagina dry, painful, red, itchy, smells, and secretes excess fluid. Dienestrol is also often prescribed to women during menopause or after menopause.

How are the rules for using Dienestrol drugs?

Vaginal estrogen products usually come with instructions for use for the patient. Read carefully before using this medication.

Wash hands before and after using the medicine. Also, keep dienestrols away from your eyes. If this medicine gets into your eyes, please wash them immediately with plenty of water. If your eyes still feel burning or painful, have them checked by your doctor.

Use this medication only as directed. Don't overuse it and don't use it for a longer time than your doctor recommends. This treatment can take up to 4 months to see the full effects of estrogen.

You may need to switch to oral estrogen for additional benefits or a higher dose. When using an estradiol vaginal insert or ring, you will need to replace it every 3 months or remove it after 3 months.

How to use dienestrol vaginal cream or suppositories:

• Do it in a relaxed position while lying on your back with your knees bent or standing with one leg on a chair.
• Hold the applicator in one hand. Insert the applicator slowly into the vagina.
• Gently press the push button until the end.
• Pull out the applicator. The medicine will be left in the vagina.

For the insertion or vaginal ring dosage form:

To insert a vaginal insertion:

• Do it in a relaxed position while lying on your back with your knees bent or standing with one leg on a chair.
• Pinch or press the insertion side of the vagina together, between the index and middle fingers.
• With one hand, separate the folds of skin around the vagina.
• Insert a vaginal insertion slowly into the upper third of the vagina. Stop if you feel uncomfortable.
• If it feels uncomfortable, then be careful when pushing the vaginal insertion into the deeper area of ​​the vagina.

To remove a vaginal insertion:

• Stand with one leg on a chair.
• Insert a finger into the vagina and hook the finger around the closest part of the vaginal insert.
• Gently pull out the vaginal insertion.
• Discard the vaginal insertion by wrapping it and throwing it in the trash. Don't flush it down the toilet.

Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

How to store Dienestrol?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Precautions & Warnings

What should be considered before using the drug Dienestrol?

Before using Dienesterol, tell your doctor if you have:

• Porphyria
• Undiagnosed abnormal vaginal bleeding
• Known or suspected estrogen-dependent neoplasia
• Deep vein thrombosis or pulmonary embolism
• Arterial thromboembolic disease
• Liver disease or disorder
• Hypersensitivity

Is the drug Dienestrol safe for pregnant and lactating women?

Animal studies have shown that dienestrol can be fatal to the fetus if used during pregnancy. Avoid using dienestrol if you are pregnant.

The use of dienetsrol is also not recommended for breastfeeding mothers. Estrogen passes into breast milk and can reduce the amount and quality of breast milk.

Side effects

What are the possible Dienestrol side effects?

Common side effects of dienestrol are:

• vaginal irritation
• dizzy
• the head feels light
• headache
• stomach ache
• bloating
• nausea
• changes in weight
• increase / decrease in interest in sex
• breast pain.
• indigestion
• dermatological reactions
• increased blood pressure (high doses)
• thromboembolic disorders
• fluid retention / edema
• decreased glucose tolerance
• hypercalcemia
• folate deficiency
• cholestatic jaundice
• liver tumor
• genitourinary effect
• mental depression
• dizzy
• altered libido
• chorea
• keratoconus
• contact lens intolerance
• hematological effect

Not everyone experiences the above side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Drug Interactions

What drugs can interfere with the drug Dienestrol?

Although certain drugs should not be used at the same time, in other cases two different drugs can be used together even if interactions are possible. In this case, your doctor may change the dose or take other precautions that may be needed. tell your healthcare professional if you are taking any prescription or nonprescription drugs on the market.

Can certain foods and drinks interfere with the work of the drug Dienestrol?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interfere with the performance of the drug Dienestrol?

The presence of other health problems in your body may affect the use of this medicine. Tell your doctor if you have other health problems.:

• Asthma
• Epilepsy
• Heart problems
• Kidney problems
• Migraine headaches - Estrogens can make this condition worse
• Blood clotting problems - Although worsening of the blood clotting condition is unlikely, some doctors do not prescribe vaginal estrogen for patients with blood clotting problems or a history of these problems.
• Breast cancer (active, suspected, or past history) - Estrogens should not be used
• Certain cancers, including breast, bone, or uterine cancer (active or suspected). Estrogens can interfere with the treatment of breast or bone cancer or worsen uterine cancer when these conditions are present.
• Cholestatic jaundice (blocked bile flow from the liver), past history - needs warning when this problem exists
• Diabetes mellitus. Estrogens can change your body's response to sugar in your diet.
• Endometriosis
• Uterine fibroid tumor. Estrogens can worsen endometriosis or increase the size of fibroid tumors.
• Gallbladder problems (gallstones). Estrogens can increase your chances of having a gallbladder attack.
• Heart attack
• Stroke (active history or in the past). Estrogens should not be used.
• Hemangioma of the liver (a non-cancerous tumor of the liver). Estrogen can make these health problems worse.
• High blood pressure. Estrogen can make these health problems worse.
• Hypercalcemia (too much calcium in the blood). Estrogen can make these health problems worse.
• Hypertriglyceridemia (too many triglycerides in your blood). Estrogen can increase the chance of getting pancreatitis or other side effects.
• Hypocalcemia (too little calcium in your blood). Your doctor should return your calcium levels to healthy limits before starting estrogen therapy.
• Vaginal irritation or infection. Usually estrogen relieves vaginal infection or irritation but sometimes therapy can make these conditions worse.
• Liver disease
• Liver problems - estrogen should not be used.
• Systemic lupus erythematosus (LES or lupus). Estrogen can make these health problems worse.
• Physical problems in the vagina, such as a narrow vagina, vaginal stenosis, or vaginal prolapse. Estradiol vaginal inserts or rings may be more likely to slip out of place or cause problems such as vaginal irritation
• Porphyria. Estrogens can make these health problems worse.
• Thyroid problems (underactive thyroid). Estrogens can change your body's response to your thyroid medications. Your doctor can change the amount of thyroid you use while on estrogen therapy
• Unusual vaginal or genital bleeding with no known cause. Using estrogen can delay diagnosis or make the condition worse. The cause of bleeding must be known before using estrogen.

Dose

The information provided is not a substitute for a doctor's prescription. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of dienestrol for adults?

The dosage of drugs in this class will be different for each patient. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If the dosage is different, do not change it unless your doctor tells you to.

The amount of medicine you have to use depends on the strength of the drug. In addition, the number of doses you take each day, the time between doses, and the length of time you take the drug will depend on your medical problem.

For conjugated estrogens vaginal cream dosage forms

Initially, 0.5 gram (g) of conjugated estrogen is introduced into the vagina once daily, or as directed by your doctor to achieve the lowest possible dose.

Usually your doctor will want you to use this drug only three weeks each month (three weeks of use, one week of stopping). The doctor may be able to increase the dose as needed. However, the dose is usually not more than 2 grams per day.

For estradiol vaginal cream dosage forms:

200-400 micrograms (mcg) of estradiol (2-4 grams of cream) are inserted into the vagina once a day for one to two weeks. Reduce dosage to one and a half if it lasts more than two and four weeks.

After four weeks, your doctor may ask you to use these medications less frequently, such as 100 mcg (one gram of cream) one to three times a week and only three weeks each month (three weeks on and one week off).

For insertion or ring dosage form estradiol:

One insertion containing 2-24.8 milligrams (mg) of estradiol is inserted into the vagina every three months. Insertion slowly releases estradiol at a rate of 7.5-100 micrograms (mcg) every twenty-four hours with continuous use.

For estrone vaginal cream dosage forms:

2-4 milligrams (mg) of estrone inserted into the vagina once daily or as directed by your doctor.

For estrone suppository dosage forms:

250-500 micrograms (mcg) inserted into the vagina once daily or as directed by your doctor.

What is the dosage of dienestrol for children?

The dosage for children has not been determined. Consult your doctor for more information.

In what dosages and preparations is dienestrol available?

Available in dosage form:

• Tablet
• Cream
• Insertion
• Suppository

What to do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (119) or immediately to the nearest hospital emergency department.

What should I do if I forget to take medicine?

For suppositories or creams used twice a week:

If you miss a dose of this medicine and remember it after 1 or 2 days, then use the missed dose as soon as possible. However, if it is almost time for your next dose, skip the missed dose and stick to your regular dosing schedule. Don't double the dose.

For creams or suppositories that are used more than twice a week:

If you miss a dose of this medicine, use it as soon as possible if you remember within 12 hours of the missed dose. However, if it is almost time for your next dose, skip the missed dose and return to your regular dosing schedule. Don't double the dose.

Hello Health Group does not provide medical consultation, diagnosis or treatment.