Sodium nitroprusside: functions, dosage, side effects, how to use

What Drug Sodium Nitroprusside?

What is sodium nitroprusside for?

Nitroprusside is a vasodilator that works by relaxing the muscles in your blood vessels and helping them to dilate (widen). This will lower blood pressure and allow blood to flow more easily through the veins and arteries.

Nitroprusside is used to treat congestive heart failure and life-threatening high blood pressure (hypertension). Nitroprusside is also used to keep blood pressure low during surgery.

Nitroprusside can also be used for purposes other than those listed in the medication guide.

How is sodium nitroprusside used?

Nitroprusside is injected into a vein via an infusion pump. You will receive this injection at a clinic or hospital.

Nitroprusside is usually given as long as needed until your body responds to the drug.

Your breathing, blood pressure, oxygen levels, and other vital signs will be closely monitored while you are receiving nitroprusside. Blood and urine may also need to be tested during treatment.

How is sodium nitroprusside stored?

This medication is best stored at room temperature, away from direct light and damp places. Do not store in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Sodium Nitroprusside dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the sodium nitroprusside dosage for adults?

Usual adult dose for hypertension emergency:

Initial dose: 0.3 mcg / kg / min IBW given by continuous infusion.

Maintenance dose: Dosage can be titrated upwards to a maximum of 10 mcg / kg / min IBW.

Usual adult dose for congestive heart failure:

Initial dose: 10 to 15 mcg / minute given by continuous infusion.

Maintenance dose: Dosage can be titrated to 10 to 200 mcg / minute.

Maximum dose: 280 mcg / minute (4 mcg / kg / min).

What is the sodium nitroprusside dosage for children?

Safety and effectiveness have not been established in pediatric patients (less than 18 years).

In what dosage is sodium nitroprusside available?

Injection of 50mg / 2mL

Sodium Nitroprusside side effects

What side effects can be experienced due to sodium nitroprusside?

Seek immediate medical help if you experience any of the following signs of an allergic reaction: hives, difficulty breathing, swelling of the face, lips, tongue, or throat.

Tell your doctor if you have serious side effects such as:

• You feel like you might pass out, even when you lie down
• shortness of breath, shortness of breath, or shortness of breath
• confusion, ears buzzing
• dizziness with nausea and vomiting, fast breathing, seizures (convulsions);
• fast, slow, irregular heartbeat
• numbness or coldness in the arms and legs or
• shivering, sweating, tremors, twitching, overactive reflexes

Milder side effects

• mild skin rash
• mild stomach pain or nausea
• warmth, redness, or tingling feels under your skin
• darkening or deeper coloration of blood vessels through your skin or
• irritation around the infusion area

Not everyone experiences this side effect. There may be some side effects not listed above. If you have any concerns about side effects, please consult a doctor or pharmacist.

Sodium Nitroprusside Drug Warnings and Cautions

What should be known before using sodium nitroprusside?

You should not use this medication if you have an allergy to nitroprusside, or if you have hereditary vision loss (Leber's disease), vision problems caused by smoking, or a history of blood clots in your brain.

Before receiving nitroprusside, tell your doctor if you have high blood pressure, kidney or liver disease, anemia (deficiency of red blood cells), seizure disorders, or a history of head injury or brain tumor.

In an emergency situation you may not have time to tell your doctor about your health condition or if you are pregnant or breastfeeding before treatment. Make sure any doctor who treats you afterward knows that you have had treatment with this medicine.

Tell your doctor right away if you have serious side effects such as breathing problems, tremors or twitching, numbness or coldness in your arms and legs, confusion, ringing in your ears, or feeling like you might pass out.

Is sodium nitroprusside safe for pregnant and lactating women?

There is no adequate research on the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category B according to the US Food and Drug Administration (FDA).

The following references the pregnancy risk categories according to the FDA:

• A = No risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated,
• N = Unknown

Sodium Nitroprusside Drug Interactions

What medicines may interact with sodium nitroprusside?

Although some drugs should not be taken at the same time, in other cases some drugs can also be used together even though interactions may occur. In such cases, the doctor may change the dose, or take other preventive measures as needed. Tell your doctor if you are taking any other over-the-counter or prescription drugs.

Tell your doctor about all the drugs you use. This includes prescription, non-prescription drugs, vitamins, and herbal products.

Can food or alcohol interact with sodium nitroprusside?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with sodium nitroprusside?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems.

Sodium Nitroprusside overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is near the time of the next dose, skip the missed dose and return to your usual dosing schedule. Do not double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.