Combantrin: functions, dosage, side effects, how to use it

Use

What is Combantrin used for?

Combantrin is a drug containing pyrantel, which is a drug that belongs to a class of drugs anthelmintic (anthelmintic). This drug class is a class of drugs commonly used to treat pinworms (enterobiasis, oxyuriasis) or other worm infections.

Combantrin is mainly used to treat various worm infections, such as pinworm infections, roundworm infections, and hookworm infections. This medicine can also be used to treat several types of worms at the same time.

The way this drug works is by paralyzing the worms in the body so that they can be excreted naturally in the feces.

This tablet-shaped drug is an over the counter medicine that you can buy at the nearest pharmacy without a doctor's prescription. Combantrin can also be used for other medical purposes not listed in this article. Contact your doctor or pharmacist for other uses of Combantrin.

How to use Combantrin?

There are several things that must be done while using this drug, namely:

• Read the packaging label to find out when to take deworming and at the recommended dosage.
• Also make sure that you know what kind of worms have infected your body. If you have any doubts, ask your doctor or pharmacist about taking medications.
• You may take this medicine before or after eating.
• Don't forget to shake the deworming container first before pouring it into a measuring spoon.
• Use a measuring spoon to make sure that you are taking the correct dosage.
• If you are taking this medication to treat a pinworm infection, do not use this medication more than once unless instructed by your doctor.
• Do not use this medication for more than 1 gram in one dose.

When using this drug, you should also pay attention to the following things:

• Use the same medication and care for the people you have physical contact with. The reason is, worms will very easily act on other people's bodies.
• Clothes, towels, sheets should be changed and washed daily. Bathrooms also need to be cleaned thoroughly.

How to store this drug?

Combantrin is best stored at room temperature and away from direct light and damp areas. Do not store in the bathroom and do not freeze.

Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush Combantrin down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed.

Consult your pharmacist or local waste disposal agency about how to safely dispose of your product.

Dose

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage of Combantrin for adults?

The dosage of Combantrin for adults is different, depending on the type of infection it infects.

Adult dosage for enterobiasis (pinworm infection)

11 milligrams / kilogram (mg / kg) (maximum 1 gram) taken by mouth once. Repeat the dosage after two weeks.

Adult dosage for hookworm infection

11 mg / kg (maximum 1 gram) taken by mouth daily for three consecutive days.

Adult dose for ascariasis (roundworm infection)

11 mg / kg (maximum 1 gram) taken by mouth once.

Consult your doctor for information about the correct Combantrin dosage for your condition. Dosage recommendations in some cases are based on body weight and will be determined by your doctor.

This medication is used as a single dose and may need to be repeated in two to three weeks. We recommend that you consult a doctor before repeating its use after two weeks.

What is the dosage of Combantrin for children?

The dosage of Combantrin for children is different, depending on the type of infection that they are infected with.

Child dosage for enterobiasis (pinworm infection)

For children two years of age and over: 11 mg / kg (maximum 1 gram). Repeated use after two weeks.

Children's dosage for hookworm infection

For children two years and over: 11 mg / kg (maximum 1 gram). Taken every day for three days in a row.

Children's dosage for ascariasis (roundworm infection)

For children two years of age and over: 11 mg / kg (maximum 1 gram) taken only once.

Consult your doctor for information about the correct Combantrin dosage for your condition. The dosage will usually be given based on body weight.

This medication is used as a single dose and may need to be repeated in two to three weeks. We recommend that you consult your doctor before repeating the use after two weeks.

Combantrin dosage has not been established in children younger than two years. This medicine may not be safe for your child who is not of age.

It is always important to understand the safety of drugs before using them. Please consult your doctor or pharmacist for more information before using this medication to treat various worm infections.

In what dosage is this drug available?

Combantrin is available in different dosage forms and dosages. In Indonesia, Combantrin is available in the following preparations:

• Syrup: 10 mL of orange flavor
• Tablets: 125 mg, 250 mg.

Side effects

What side effects can be experienced due to Combantrin?

Like the use of other medicines, the use of Combantrin can cause some side effects. Most of the following side effects are rare and do not require additional treatment.

However, it is important that you consult your doctor if you have any problems after taking this medicine.

There are several side effects of deworming medicine that may occur after you take Combantrin. The side effects that are listed include the following:

• Stomach ache
• Gag
• Diarrhea
• Loss of appetite
• Stomach cramps
• Sleep disturbance
• Easily sleepy
• Headache
• Anorexia

Call your doctor immediately and stop using the drug if you experience an allergic reaction as follows:

• Skin rash
• Skin feels itchy
• Difficulty breathing
• Chest tightness
• Swelling of the mouth, face, lips, or tongue

Even so, not everyone experiences the side effects mentioned above. There may be some side effects not listed above.

If you have concerns about certain side effects after taking Combantrin, consult your doctor or pharmacist.

Warnings & Precautions

What should be known before using Combantrin?

Before using Combantrin, there are a number of things you should know and do, including:

• Do not use Combantrin until you tell your doctor if you are pregnant or breastfeeding.
• Make sure you discuss the benefits and risks of using this medicine for you and your baby when you want to use this medicine.
• Do not give Combantrin to children less than two years of age.
• Avoid activities that require high concentration such as driving, because this drug can interfere with your concentration.
• Tell your doctor if you have any allergies to this drug.
• Also tell your doctor if you have allergies to other medicines, foods, dyes, preservatives, or even allergies to animals.
• Tell your doctor and pharmacist about any prescription, non-prescription drugs, vitamins, and herbal medicines you use, especially piperazine (another worm infection medication).
• Tell your doctor if you have certain health conditions, especially liver problems, because this drug can interact with the disease.
• Tell your doctor right away if you still find worms in your stool or if your symptoms don't go away or if they get worse.
• Also call your doctor if you think you have symptoms of another type of worm infection.

Also, keep in mind that worm infections are very easy to attack those around you, especially those with whom you live.

Therefore, it is advisable for people who live with you, or if you live with someone who is infected with worms, get tested and treated immediately so that they can prevent the spread of the infection.

Is this drug safe for pregnant and lactating women?

There is no adequate research on the risks of using Combantrin in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication.

However, pyrantel medicine was included in it pregnancy risk category C according to the US Food and Drug Administration (FDA). The following references the pregnancy risk categories according to the FDA:

• A = No risk,
• B = not at risk in several studies,
• C = May be risky,
• D = There is positive evidence of risk,
• X = Contraindicated
• N = Unknown

It is not known whether this drug can be released from breast milk (ASI) so, if you want to use this drug while breastfeeding, consult your doctor or pharmacist.

Only use this medicine when you are pregnant and breastfeeding if the benefits of using this medicine outweigh the risk of side effects you may experience.

Always consult your doctor before using any kind of medicine to avoid unwanted things.

Interaction

What other medicines may interact with Combantrin?

Combantrin may interact with other drugs you are currently taking, which can change how your medication works or increase your risk of serious side effects.

To avoid drug interactions, you should keep a list of all the drugs you use (including prescription drugs, non-prescription drugs and herbal products) and tell your doctor and pharmacist.

For your safety, do not start, stop using, or change the dosage of any of the medicines listed below without your doctor's approval.

Although certain drugs should not be used at the same time, in certain cases, two different drugs can be used together, even if interactions are possible.

In this case, your doctor may change the dose, or take other precautions that may be needed. Tell your health care professional if you are taking any other prescription or nonprescription drugs.

There are two types of drugs that may interact with Combantrin, namely:

• sodium iodide i-123 (ARI Sodium Iodide (I123) 1-12 MBq, ARI Sodium Iodide (I123) 100-750 MBq)
• sodium iodide-i-131 (Hicon, Iodotope, i3odine Max)

Can food or alcohol interact with this drug?

Certain drugs cannot be used with meals or when eating certain foods because drug interactions can occur.

Smoking tobacco or consuming alcohol with certain drugs, including Combantrin, can also cause interactions to occur.

Talk to your healthcare professional about using drugs with the food, alcohol, or tobacco you are using.

What health conditions can interact with this drug?

Combantrin has the potential to interact with your health condition. These interactions can worsen your health condition or change the way the drugs work and increase the risk of side effects from Combantrin. It is important to always let your doctor and pharmacist know all your current medical conditions.

There is only one health problem that is known to interact with this drug, which is liver disease (liver). If you want to use Combantrin but have these health conditions, contact your doctor whether using Combantrin is safe for you.

Overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (119) or immediately to the emergency department of the nearest hospital.

Symptoms of an overdose that may occur from using this drug are fainting or shortness of breath.

Hello Health Group does not provide medical advice, diagnosis or treatment.