Ornidazole: functions, dosage, side effects, how to use

Use

What is Ornidazole for?

Ornidazole is a drug that fights protozoa and anaerobic bacteria. These drugs are converted into reduction products that interact with DNA to destroy the structure and helical strands of DNA, and cause inhibition of protein synthesis and cell death in susceptible organisms.

How do you use Ornidazole?

Must be used with food.

How to store Ornidazole?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Dose

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of Ornidazole for adults?

Oral

• For amoebiasis: 0.5 g twice daily for 5-10 days.
• For amoebic dysentery: 1.5 g as a single daily dose for 3 days. Alternative for patients> 60 kg: 1 g twice daily for 3 days.
• For giardiasis: 1-1.5 g as a single daily dose for 1-2 days.
• For trichomoniasis: 1.5 g as a single daily dose or 0.5 g twice daily for 5 days. Use in conjunction with a sexual partner.

Intravenous

• For severe amoebic dysentery: Initially, 0.5-1 g infusion followed by 0.5 g every 12 hours for 3-6 days.
• For amoebic liver abscess: Initially, 0.5-1 g infusion followed by 0.5 g every 12 hours for 3-6 days.
• For anaerobic bacterial infections: Initially, 0.5-1 g followed by 1 g daily as a single dose or in 2 divided for 5-10 days. The dose is given by infusion. Change to 500 mg orally every 12 hours as soon as possible.
• For prophylaxis of postoperative anaerobic bacterial infections: 1 g by infusion about 30 minutes before surgery.

What is the dosage of Ornidazole for children?

Oral

• For amoebiasis: 25 mg / kg as a single daily dose for 5-10 days.
• For amoebic dysentery: 40 mg / kg per day.
• For giardiasis: 30-40 mg / kg per day.
• For trichomoniasis: 25 mg / kg as a single dose.

Intravenous

• For amoebic dysentery weight: 20-30 mg / kg per day.
• For amoebic liver abscess: 20-30 mg / kg per day.
• For anaerobic bacterial infections: 10 mg / kg every 12 hours for 5-10 days.

In what dosage and preparation is Ornidazole available?

Ornidazole is available in the following dosages:

Tablet

Side effects

What side effects may occur due to Ornidazole?

Drowsiness, headache, nausea, vomiting, dizziness, tremors, stiffness, poor coordination, seizures, fatigue, vertigo, temporary loss of consciousness and signs of peripheral sensory or mixed nerve pain, taste disturbances, abnormal LFT, skin reactions.

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Precautions & Warnings

What should be known before using Ornidazole?

Kidney and liver damage. CNS diseases such as epilepsy or multiple sclerosis. May interfere with the ability to drive or operate machinery. Pregnancy and lactation.

Is Ornidazole safe for pregnant or breastfeeding women?

There is not yet sufficient information about the safety of using this medicine during pregnancy and breastfeeding. Always consult your doctor to weigh the potential benefits and risks before using this medication.

Interaction

What medicines may interact with Ornidazole?

Although some drugs should not be taken at the same time, in other cases some drugs can also be used together even though interactions may occur. In such cases, the doctor may change the dose, or take other preventive measures as needed. Tell your doctor if you are taking any other over-the-counter or prescription drugs.

Can food or alcohol interact with Ornidazole?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions may interact with Ornidazole?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems.

Overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (119) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.