Iopamidol: functions, dosage, side effects, how to use

What drug Iopamidol?

What is Iopamidol used for?

Iopamidol belongs to a group of drugs called radiopaque, a contrast agent. Iopamidol contains iodine, a substance that absorbs X-rays. Radiopaque contrast agents are used to allow blood vessels, organs, and other non-bone tissue to be seen more clearly on a CT scan or other radiological examination (X-ray). Iopamidol is commonly used to help diagnose certain disorders of the heart, brain, blood vessels, and nervous system. Iopamidol can also be used for medications that are not listed in the Medication Guide.

How is Iopamidol used?

Iopamidol is injected into a vein or artery through an IV. The health care provider will provide this injection. You may be given medication to prevent certain side effects while you are receiving Iopamidol. Tell your doctor if you feel burning, pain, or swelling around the IV needle when Iopamidol is injected. Drink extra fluids before and after undergoing radiological tests. Iopamidol can cause dehydration which is dangerous to the kidneys. Follow your doctor's instructions regarding the type and amount of fluids to drink before and after the test.

Adults may need special care to avoid dehydration. Kidney function needs to be checked after receiving Iopamidol. Some people who receive Iopamidol experience no reaction 30-60 minutes after the drug is first given. The nurse will monitor you for a few moments after the injection to make sure you don't experience any unwanted side effects or delayed reactions.

This medication may cause unusual results with certain medical tests. Tell the nurse doctor that you are taking Iopamidol.

How is Iopamidol stored?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Rules of Use Iopamidol

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage for Iopamidol for adults?

Intravenous

Peripheral venography

Adults: Use 200 mg iodine / ml (41% Iopamidol injection). 25-150 ml per lower limb. The total dose for several injections should not exceed 350 ml.

Intravenous

Excretory urography

Adults: 250 mg iodine / ml (Iopamidol inj 51%): 50-100 ml; 300 mg iodine / ml (61% Iopamidol injection): 50 ml; 370 mg iodine / ml (76% Iopamidol injection): 40 ml. administer by rapid IV injection.

Intravenous

Computed tomography imaging

Adult: Head: 250 mg iodine / ml (injection of Iopamidol 51%): 130-240 ml; 300 mg iodine / ml (61% Iopamidol injection): 100-200 ml. Manage by IV infusion. Body: 250 mg iodine / ml (51% Iopamidol injection): 130-240 ml; 300 mg iodine / ml (Iopamidol inj 61%): 100-200 ml. Manage by rapid IV infusion or bolus injection. The total dose for the procedure should not exceed 60 g of iodine.

Intra-arterial

Cerebral arteriography

Adults: Use 300 mg iodine / ml (Iopamidol injection 61%). Carotid puncture or transfemoral catheterization: 8-12 ml. A total of several doses for the procedure up to 90 ml.

Intra-arterial

Peripheral arteriograph

Adults: Use 300 mg iodine / ml (Iopamidol injection 61%). Femoral or subclavian artery: 5-40 ml. Aorta for distal states: 25-50 ml. Up to 250 ml have been used.

Intra-arterial

Selective visceral arteriography or aortography

Adults: Use 370 mg iodine / ml (Iopamidol injection 76%). Larger blood vessels eg aorta or celiac artery: Up to 50 ml. Renal artery: Up to 10 ml. Lower doses are often sufficient. Multiple dosage amounts up to 225 ml have been used.

Intra-arterial

Coronary arteriography and ventriculography

Adults: Use 370 mg iodine / ml (76% Iopamidol injection). Selective coronary arteries: 2-10 ml. Ventriculography or selective opacification of multiple coronary arteries followed by injection of the aortic root: 25-50 ml. The total dose for the combined procedure up to 200 ml has been used. ECG monitoring is essential.

What is the dosage of Iopamidol for children?

Intravenous

Angiocardiography

Children: Use 370 mg iodine / ml (76% Iopamidol injection). For single injection: <2 years: 10-15 ml; 2-9 yr: 15-30 ml; 10-18 yrs: 20-50 ml. Manage by injection into a large peripheral vein or by direct cardiac catheterization. For cumulative injection: <2 years: 40 ml; 2-4 yr: 50 ml; 5-9 yr: 100 ml; 10-18 yrs: 125 ml.

Intravenous

Excretory urography

Children: Children: 250 mg iodine / ml (51%): 1.2-3.6 ml / kg; 300 mg iodine / ml (61%): 1-3 ml / kg. Maximum dose for the procedure: 30 g of iodine.

Intravenous

Computed tomography imaging

Children: 250 mg iodine / ml (51% Iopamidol injection): 1.2-3.6 ml / kg; 300 mg iodine / ml (61% Iopamidol injection): 1-3 ml / kg. The total dose should not exceed 30 g of iodine.

In what dosage is Iopamidol available?

Injection: 41%, 61%, 76%.

Iopamidol dosage

What side effects can iopamidol have?

Seek immediate medical help if you experience any of the following signs of an allergic reaction: hives, difficulty breathing, swelling of the face, lips, tongue, or throat.

Call your doctor right away if you experience:

• dizzy, like about to pass out
• swelling, rapid weight gain, little or no urination
• difficulty breathing or wheezing
• Seizures
• swelling of the neck or throat (enlarged thyroid)
• heart attack symptoms, chest pain or pressure, pain spreading to the jaw or shoulder, nausea, sweating
• signs of a stroke: sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, impaired vision or balance
• signs of a blood clot in the lungs: chest pain, cough suddenly, wheezing, rapid breathing, coughing up blood

Common side effects include:

• chest pain
• slow heart rate
• heat, burning sensation
• flushing (warmth, redness, or tingling feeling)
• nausea
• itchy rash
• dizzy

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Iopamidol side effects

What should be known before using iopamidol?

What should be known before using Iopamidol?

Tell your doctor if you have had any reactions to other types of contrast agents.

Is Iopamidol safe for pregnant and lactating women?

There is not sufficient research to determine the risks of using the medication in women during pregnancy or breastfeeding. Always consult your doctor to weigh the potential benefits and risks before using this medication. This medicine falls into the risk category of pregnancy D.

A = no risk

B = no risk in several studies

C = there may be a risk

D = tested positive for risk

X = contraindicated

N = unknown

Iopamidol can pass into breast milk and harm a nursing baby. Tell your doctor if you are breastfeeding a baby.

Iopamidol Drug Warnings and Cautions

What medicines may interact with iopamidol?

Drug interactions can change the performance of the drug or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Can food or alcohol interact with Iopamidol?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with Iopamidol?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

• liver or kidney disease
• heart disease, including congestive heart failure
• a history of stroke, blood clots, or coronary artery disease
• asthma, hay fever, food allergies
• epilepsy or other seizure disorder
• sickle cell anemia
• diabetes
• active infection
• pheochromocytoma (tumor of the adrenal glands)
• multiple myeloma (bone cancer)
• thyroid disorders

Iopamidol Drug Interactions

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

Because Iopamidol is only used during radiological tests, you will not need a dosage schedule for the drug.

Hello Health Group does not provide medical advice, diagnosis or treatment.