Midazolam: functions, dosage, side effects, how to use

What Medication Midazolam?

What is Midazolam for?

Midazolam is an anesthetic drug that belongs to the benzodiazepine group. This drug acts directly on the central nervous system by increasing the response of nerve cells which are responsible for sending the signal "calm". By taking medication, a person will feel more relaxed, sleepy, or unconscious.

Usually the doctor will give this drug before the surgical procedure. In addition, this drug can also be used to treat other conditions which include:

• Psychological problems such as anxiety disorders, excessive panic, and acute depression
• Prevent as well as overcome seizures
• Remove the alcohol
• Sleep disorders such as insomnia

It is important to know that you cannot just get this drug. This is because the benzodiazepine class of drugs is included in the list of drugs that must be redeemed by a doctor's prescription.

While using this drug, you may be closely monitored by a doctor or nurse. This is done to monitor your body's overall health response to treatment.

Your doctor may also be able to prescribe this medication for other purposes that are not described in the following article. Please ask your doctor and pharmacist for more information.

How to use Midazolam?

Midazolam is an anesthetic drug that must be used under a doctor's supervision. You are not allowed to use this medication on your own. As a result, you have to go to a clinic or hospital to get one.

This medication is usually given as a single dose before any surgical or surgical procedure takes place. The dosage is adjusted to the medical condition and the patient's response to the drug.

This medicine can cause shortness of breath, especially if you are taking opioid drugs. Therefore, before using this medicine, make sure you tell the doctor and nurse about all medicines that you are currently using or will be using regularly.

After the medication has been successfully administered, you will be closely monitored by doctors and nurses. Your blood pressure, pulse and oxygen levels will be continuously monitored. This is done to ensure that the drug works optimally and does not cause dangerous side effects.

It's also important to note that this drug can cause a withdrawal reaction. This condition generally occurs if you use the drug for a long time or in high doses. Drug reactions are characterized by a number of characteristic symptoms such as shaking, profuse sweating, vomiting, stomach and muscle cramps, and convulsions.

A withdrawal reaction may also be triggered because you suddenly stop using this drug. To prevent these reactions, the doctor may reduce the dose gradually. Please consult a doctor or nurse for more information.

Avoid eating grapefruit or drinking grapefruit juice while using this medicine. The reason is, the fruit can increase the amount of certain drugs in the bloodstream, which can trigger side effects.

Basically, use whatever medication your doctor recommends or is listed on the drug packaging label. Don't hesitate to ask your doctor or pharmacist directly if you don't really understand how to use it.

In addition, consult a doctor immediately if the condition does not improve or gets worse. Your doctor can change the dose of your medication or prescribe another one that's safer for you.

How to store Midazolam?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it.

Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed.

Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Midazolam dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dosage of Midazolam for adults?

Only doctors or medical personnel may give this drug to patients. The dosage for each person can be different. The dose of the drug is adjusted according to the patient's age, overall health condition, and their response to treatment.

Be sure to always consult a doctor or pharmacist before taking any type of medication. This is to ensure that you are taking the drug according to the recommended dosage.

What is the dosage of Midazolam for children?

Dosage for children is based on their age and body weight. Doctors also consider the child's health condition and response to medications.

Therefore, the dosage of medicine for each child can be different. To find out the exact dosage, please consult directly to a doctor.

In what dosage is Midazolam available?

Midazolam is an anesthetic that is available as an injectable liquid.

Midazolam side effects

What side effects can be experienced due to Midazolam?

Depending on the size of the medical procedure that you are going to undergo, the doctor will usually inject an anesthetic to numb pain in the body during surgery or surgery. This anesthetic can make a patient immune from aches and pains for a while. Even so, that does not mean the drug is free of risk of side effects.

Here are some of the most common and frequently complained about side effects of anesthetics:

• Amnesia or mild memory loss after undergoing the procedure
• Sleepy
• Dizzy
• Mild headaches
• Nausea and vomiting
• Runny nose
• Sneezing
• Blurred vision
• Limp body is not powerful

The sedative effect of the drug Midazolam will generally last longer in the elderly (elderly). This makes parents more at risk of falling. Therefore, make sure your parents (seniors) get extra tight supervision so you don't experience these side effects.

This medication can also cause a severe allergic reaction known as anaphylactic shock. When this happens, you will experience:

• Skin rash
• Itchy rash
• Difficulty breathing
• Swelling of the face, lips, tongue, or throat
• Consciousness was almost lost

You should also tell your nurse or doctor immediately if you have chronic cough, difficulty breathing, very weak body, slow heartbeat, and hallucinations.

Not everyone experiences the side effects mentioned above. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Midazolam Drug Warnings and Cautions

What should be known before using Midazolam?

Some things you need to know and do, before using Midazolam are:

• Tell your doctor and nurse if you have any allergies to midazolam or other benzodiazepine drugs, such as alprazolam, chlordiazepoxide, clorazepate, diazepam, lorazepam, or oxazepam. Ask them for a list of the ingredients that make up the drug you are going to use.
• Tell your doctors and nurses if you are, will, or have routinely taken certain medications. Including prescription drugs, non-prescriptions, to medicines made from herbal ingredients, especially St. John's Wort.
• Tell your doctor and nurse if you have a history of narrow and open angle glaucoma.
• Tell your doctor and nurse if you have a history of chronic respiratory disease, including asthma, emphysema, bronchitis, COPD, and other conditions.
• Tell your doctor and nurse if you have a history of chronic liver disease.
• Tell your doctor and nurse if you have a history of congestive heart failure.
• Tell your doctors and nurses if you have a history of addiction to certain drugs or alcohol.

You should also tell your doctor and nurse if you are planning to become pregnant, are pregnant, and are actively breastfeeding. Because, this drug has the potential to cause birth defects in the fetus.

On the other hand, this drug is also reported to pass into breast milk so that it has the potential to harm the baby. Therefore, this medicine generally should not be used during pregnancy and should be used with caution in nursing mothers.

You also need to know that this drug can make you drowsy, affect memory, dizziness, and feel weak. We recommend that you avoid driving a car / motorcycle and other activities that require high alertness until the effects of the drug are completely gone.

The side effects of dizziness from this drug may also make a person prone to falling. Especially in the elderly (elderly). To help avoid this problem, ask them to get out of bed slowly. Place your feet on the floor for a few minutes before standing.

In addition, be sure to follow all doctor's advice and / or therapist's instructions. Your doctor may need to change your medication dose or monitor you carefully to prevent certain side effects.

Is Midazolam safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication.

According to the US Food and Drug Administration (FDA), this drug is a pregnancy riskcategory D.

The following references the pregnancy risk categories according to the FDA:

• A = Not at risk
• B = No risk in several studies
• C = May be risky
• D = There is positive evidence of risk
• X = Contraindicated
• N = Unknown

Because this medicine is in category D, avoid taking it while pregnant. If you have recently become pregnant, stop taking it immediately.

This is because midazolam can cause injury or death to the fetus especially if it is taken during the second or third trimester.

Meanwhile, for breastfeeding mothers, there is no clear evidence whether this drug harms the baby or not. To avoid various negative possibilities, do not take this medicine carelessly or without the doctor's permission.

Midazolam Drug Interactions

What medicines may interact with Midazolam?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this article.

Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

Using midazolam with other medicines that make you drowsy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before using this medication with sleeping pills, narcotic pain medicine, muscle relaxer, or medication for anxiety, depression, or seizures.

Many drugs can interact with this anesthetic. Unfortunately, not all interactions are listed here. Tell your doctor about all medications you are, have, or will use while using this anesthetic, in particular:

• Bored
• Imatinib
• Nefazodone
• St. John's Wort
• Antibiotics such as clarithromycin, erythromycin, telithromycin
• Antifungal drugs eg itraconazole, ketoconazole, posaconazole, voriconazole
• Heart medications such as nicardipine and quinidine
• Hepatitis C drugs such as boceprevir and telaprevir
• HIV / AIDS drugs including atazanavir, delavirdine, efavirenz, fosamprenavir, indinavir, nelfinavir, nevirapine, ritonavir, and saquinavir
• Seizure drugs, namely carbamazepine, fosphenytoin, oxcarbazepine, phenobarbital, phenytoin, and primidone
• TB drugs which include isoniazid, rifabutin, rifampin, and rifapentine

Can food or alcohol interact with Midazolam?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur.

Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions may interact with Midazolam?

The presence of other health problems in your body can affect the use of this drug. Tell your doctor if you have other health problems, especially:

• Sleep disturbance
• Heart disease
• Hypoventilas
• Infection
• Chronic lung disease
• Blockage of the lungs or airway
• Congenital heart failure
• Kidney illness
• Liver disease
• Glaucoma, acute narrow angle

Midazolam overdose

In case of an emergency or overdose, contact the local emergency services provider (119) or immediately to the nearest hospital emergency department. Bring a medicine box, container, or label with you when you go to the hospital to help the doctor with any necessary information.

When someone has an overdose, various symptoms that may arise are:

• Too low blood pressure (hypotension) which makes the head dizzy
• Fainting
• Fast and irregular heartbeat
• Slower than normal heart rate

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and continue on your dosing schedule. Do not use extra doses to make up for a missed dose.

If you continue to miss doses, consider setting an alarm or asking a family member to remind you.

Please consult with your doctor to discuss changes in your dosing schedule or a new schedule to make up for a missed dose, if you have missed too many doses recently.

Hello Health Group does not provide medical advice, diagnosis or treatment.