Pergolide: functions, dosage, side effects, how to use it

What is the drug Pergolide?

What is the drug Pergolide used for?

Pergolide is a drug used to treat Parkinson's disease. Parkinson's disease is associated with low levels of the chemical dopamine in the brain. Pergolide has some of the same effects as dopamine in the body.

Pergolide is used to treat stiffness, tremors, spasms, and weak muscle control due to Parkinson's disease. Pergolide is often used together with other drugs in the treatment of Parkinson's disease.

Pergolide may also be used for purposes other than those listed in the medication guide.

What are the rules for using Pergolide drugs?

Use the pergolide exactly as directed by your doctor. If you do not understand the directions for use on the product flyer, ask your pharmacist, nurse or doctor to explain it to you.

Take medicine with a glass of water.

It is important to use pergolide regularly to reap its benefits.

Don't stop using pergolide without talking to your doctor first. Stopping the use of pergolide suddenly can cause dangerous side effects such as high body temperature, muscle stiffness, confusion or altered consciousness, and other problems.

Your doctor may want you to have blood tests or other medical tests during treatment with pergolide to monitor progress and side effects.

Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

How to save Pergolide?

This medication is best stored at room temperature, away from direct light and damp places. Don't keep it in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product package or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medicines down the toilet or down the drain unless instructed to do so. Discard this product when it has expired or when it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.

Pergolide dosage

What should be considered before using the drug Pergolide?

Do not use pergolide mesylate if:

• You are allergic to any of the ingredients in pergolide mesylate
• You are allergic to any type of ergot medicine (for example, ergotamine)

Is the drug Pergolide safe for pregnant and lactating women?

There are no adequate studies regarding the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the pregnancy risk category B_ according to the US Food and Drug Administration (FDA). (A = No risk, B = No risk in some studies, C = Possible risk, D = Positive evidence of risk, X = Contraindicated, N = Unknown)

Warning for Breastfeeding Mothers

There are no data on the excretion of pergolide into human milk. The manufacturer recommends that because of the potential for serious side effects in a nursing infant, a decision should be made to stop breastfeeding or stop using the drug taking into account the importance of the drug to the mother.

Pergolide side effects

What are the possible side effects of Pergolide?

Rarely happening

• Chest pain (severe)
• Seizures
• Difficulty breathing
• Fainting
• Fast or irregular heartbeat
• Headache (severe or continuous)
• High fever
• High or low blood pressure (irregular)
• Heavy sweating
• Loss of bladder control
• Nausea and vomiting (persistent or severe)
• Twitter
• Severe muscle stiffness
• Sudden weakness
• Urgent breath without cause
• Unusual fatigue or weakness
• Unusually pale skin
• Vision changes, such as blurred vision or temporary blindness

More common

• Anxiety
• Bloody or cloudy urine
• Confusion
• Urinating is difficult or painful
• Frequent urination
• Hallucinations (seeing, hearing, or feeling things that don't exist)
• Uncontrolled movements of the body, such as the face, tongue, arms, hands, head, and upper body

Less common

• Dizzy
• Headache
• Swelling of the hands and feet

Rarely happening

• Abdominal pain or feeling of pressure
• Chills
• Cough
• Less urine flow than usual
• Fever
• Pain in the side or lower back

Some of the side effects of pergolide may not require medical attention. As your body gets used to this drug, the side effects may go away. Your healthcare provider may be able to help you prevent or reduce these side effects, but check with them if any of the following side effects persist, or if you are concerned:

More common

• Asphyxiate
• Constipation
• Dizziness or lightheadedness, especially when getting up from a lying or sitting position
• Drowsiness
• Heartburn
• Lower back pain
• Muscle ache
• Nausea
• Runny nose or congestion
• Trouble sleeping
• Weakness

Less common

• Diarrhea
• Dry mouth
• Loss of appetite
• Swollen face
• gag

Not everyone experiences the following side effects. There may be some side effects not listed above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Pergolide Drug Warnings and Cautions

What medicines can interfere with the drug Pergolide?

Drug interactions can change the performance of your medications or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval

Dopamine antagonists, such as neuroleptics (phenothiazines, butyrophenones, thioxanthines) or metoclopramide, should not usually be given at the same time as Permax (pergolide mesylate) (dopamine agonists); these agents can reduce the effectiveness of Permax. Since pergolide mesylate is approximately 90% plasma protein bound, caution should be exercised if it is used in conjunction with other drugs known to affect protein binding.

Can certain foods and drinks interfere with the action of the drug Pergolide?

Certain drugs should not be used with meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interfere with the performance of the drug Pergolide?

The presence of other health problems in your body may affect the use of this drug. Tell your doctor if you have other health problems.

Pergolide Drug Interactions

The information provided is not a substitute for a doctor's prescription. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of the drug Pergolide for adults?

Usual Adult Dose for Parkinson's Disease:

Pergolide was voluntarily withdrawn from the US market by manufacturers in March 2007 due to increasing reports of serious heart valve damage. The following dosage information applies when this drug is available in the US

Baseline: 0.05 mg orally once a day for the first 2 days.

Maintenance: Gradually increasing

an increase of 0.1-0.15 mg every third day for the next 12 days. Then increase by 0.25 mg every third day until the optimal dose is achieved.

The daily dose is usually divided into 3 to 4 doses / day. The average dose is 3 mg / day. Doses above 5 mg / day have not been studied.

Usual Adult Dose for Hyperprolactinemia:

Pergolide was voluntarily withdrawn from the US market by manufacturers in March 2007 due to increasing reports of serious heart valve damage. The following dosage information applies when this drug is available in the US

Initial: 0.05 mg orally once a day.

Can be increased in increments of 0.025-0.05 mg as needed to control prolactin levels.

Most patients receive 0.1 mg orally once a day.

What is the dose of the drug Pergolide for children?

Usual Children's Dose for Tourette Syndrome:

Pergolide was voluntarily withdrawn from the US market by manufacturers in March 2007 due to increasing reports of serious heart valve damage. The following dosage information applies when this drug is available in the US

Study (n equals 18), duration 1 month:

8 to 17 years: initially 25 mcg / day, 2 to 3 days later the dose is titrated to 50 mcg three times a day, then titrated increased every 3 days with 50 mcg per dose with a final dose of 150 mcg three times a day. The maximum dose used in 4 patients was 300 mcg three times daily.

In what dosages and preparations is Pergolide available?

Tablet:

0.05mg

0.25 mg

1 mg

What to do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (118/119) or immediately to the nearest hospital emergency department.

What should I do if I forget to take medicine or forget to take medicine?

If you forget a dose of this medicine, take it as soon as possible. However, when it is nearing the time of the next dose, skip the missed dose and return to the usual dosing schedule. Don't double the dose.

Hello Health Group does not provide medical consultation, diagnosis or treatment.