Pratifar: functions, dosage, side effects, how to use it

Use

What is the preliminary medicine for?

Pratifar is a brand of oral tablet that contains famotidine as an active ingredient. Famotidine belongs to the H2 drug class blockers or it could be called an H2 antagonist. This class of drugs works by reducing the amount of acid that is formed in the stomach.

Therefore, this drug can be used to treat several conditions, such as the following.

• Active doudenum ulcer
• Active gastric ulcer
• Gastroesophageal reflux disease (GERD), which is stomach acid disease
• Erosive esophagitis, or inflammation of the esophagus caused by GERD
• The stomach produces excess acid, such as Zollinger-Ellison syndrome
• Dyspepsia, or stomach pain

Pratifar is included in a type of prescription drug, so you are only allowed to buy this drug at a pharmacy if it is accompanied by a prescription from your doctor.

How do I use the pratifar?

The following points should be taken into account when using pratifications. Among them:

• Use pratifar according to the prescription that has been given by the doctor.
• This medicine may be used when the stomach is still empty or has been filled with food.
• While using this medication, it may take 4 weeks of use to completely heal. Use the medicine as directed.
• If your condition does not improve or gets worse after taking this drug, contact your doctor immediately.
• Pratifar is usually only one part of the course of treatment. So, you may also need to exercise regularly and adjust your diet.
• To get maximum medicinal benefits, use Pratifar regularly at the same time every day.
• Doctors usually determine the dose of this drug based on your health condition and response to treatment.
• For children, the dose is usually also determined based on body weight.
• You may take other drugs, such as antacid medicines, along with this medicine. But make sure the doctor knows the use of these other drugs.

How do I save the pratifar?

As with other medicines, you can save pratifar with the following rules:

• Store the pratifar at room temperature.
• Keep pratifar away from damp places.
• Keep this medication away from exposure to sunlight or direct light.
• Do not store pratifar in the bathroom or in the freezer, let alone frozen.
• Keep this medication out of reach of children and pets.

If this drug has not been used, you can dispose of it with the following rules:

• Discard this medication if it has expired or is no longer used.
• Do not flush it down the drain or in the toilet.
• If you do not know or have doubts about the proper disposal procedure for drug waste, do not hesitate to ask your pharmacist or staff to find out about safe disposal of drug waste.

Dose

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the preliminary dose for adults?

Adult dosage for gastric ulcers

• 40 milligrams (mg) taken by mouth once a day at bedtime.
• Maximum drug use: 6 weeks

Adult dosage for peptic ulcers

• 40 mg taken by mouth once a day at bedtime, or 20 mg taken by mouth twice daily
• Maintenance dose: 20 mg orally once a day at bedtime
• Maximum drug use: 4 weeks

Adult dosage for dyspepsia

• Treatment dose: 10-20 mg orally once
• Preventive dose: 10-20 mg taken by mouth once at least one hour before eating foods that can cause the chest to experience a burning sensation.
• Maximum dose: two tablets a day
• Maximum drug use: 2 weeks

Adult dosage for erosive esophagitis

• 20-40 mg orally twice a day
• Maximum drug use: 12 weeks

Adult dosage for treating acid reflux disease (GERD)

• 20 mg orally twice a day
• Maximum drug use: 6 weeks

Adult dosage for Zollinger-Ellison syndrome

• Initial dose: 20 mg orally every 6 hours
• Maximum dose: 160 mg orally every 6 hours

What is the preliminary dose for children?

Children's dosage for peptic ulcer

• For children aged 1-16 years:
  • Take 0.5 mg / kilogram (kg) of body weight once a day at bedtime, or 0.25 mg / kg of body weight orally twice a day.
  • Maximum daily dose: 40 mg / kg
• For children 16 years and over:
  • 40 mg taken by mouth once a day before bed, or 20 mg taken by mouth twice daily
  • Maintenance dose: 20 mg orally once a day at bedtime
  • Maximum drug use: 4 weeks

Children's dosage for acid reflux disease (GERD)

• For children aged 1-2 months:
  • Initial dose: 0.5 mg / kg orally once a day
  • Maximum use of the drug: up to 8 weeks
• For children aged 3-11 months:
  • Initial dose: 0.5 mg / kg / day orally twice a day
  • Maximum use of the drug: up to 8 weeks
• For children aged 1-16 years:
  • Initial dose: 0.5 mg / kg / day orally twice a day
  • The maximum dose is 40 mg
• For children 16 years and over:
  • 20 mg taken twice a day
  • Maximum drug use: 6 weeks

Children's dosage for dyspepsia

• For children 12 years and over:
  • Treatment dose: 10-20 mg orally once a day
  • Preventive dose: 10-20 mg taken by mouth once at least one hour before eating foods that can cause the chest to experience a burning sensation
  • Maximum dose: 2 tablets daily
  • Maximum drug use: 2 weeks

In what dosage is Pratifar available?

Tablets: 20 mg, 40 mg

Side effects

What are the possible side effects of using Pratifar?

As with medicines in general, the use of pratatives can also cause side effects, both minor and serious. The following are mild side effects that are more common, such as:

• Headache
• Dizzy
• Constipation
• Diarrhea
• Crying without cause (usually in children)

Although mild and can go away on their own, these side effects may get worse. If your condition does not improve, contact your doctor immediately. In addition, there are also more serious side effects of drugs that you should stop using the drug if you experience these side effects, such as:

• Seizures
• Hallucinations and lack of energy
• The heart beats fast
• The body feels like passing out
• Muscle pain, usually accompanied by fever, unusual fatigue, and dark urine
• Allergic reactions such as swelling of the throat, tongue, lips, hands, feet, ankles and calves.

Not all drug side effects are listed above. There are even side effects that you may feel that are not listed. However, not all users of this drug experience side effects from using the drug. If you have any doubts about the side effects you will experience when using Pratifar, contact your doctor immediately.

Precautions & Warnings

What should be known before using pratification?

Some of the following things you should know and understand before deciding to use pratification. Among them:

• Tell your doctor if you have kidney or liver problems, stomach cancer, asthma, or other respiratory problems.
• Tell your doctor if you have an allergy to pratifar or the main active ingredient of this medicine, namely famotidine. Also, tell your doctor if you have any other allergies to similar drugs (ranitidine, cimetidine, nizatidine).
• Tell your doctor all types of medicines you are currently using or intend to use, whether prescription drugs, non-prescription drugs, multivitamins, and herbal products. It is important to avoid drug interactions.
• Tell your doctor if you have phenylketonuria, a condition in which mental retardation can form if you eat certain foods.
• Tell your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.
• Do not take other medicines without your doctor knowing.

What are the safe precautions for pregnant and lactating women?

It is not certain whether this drug will have certain effects on pregnant women and their fetuses. However, if you must use this drug, ask your doctor whether this drug is safe for consumption by pregnant women. Even so, this drug is included in the risk of pregnancy category B by the Food and Drug Administration (FDA) or the equivalent of the Food and Drug Administration (BPOM) in Indonesia. The following references the pregnancy risk categories according to the FDA:

• A: No risk,
• B: No risk in some studies,
• C: May be risky,
• D: There is positive evidence of risk,
• X: Contraindicated,
• N: Not known

Likewise with breastfeeding mothers, if you must use this drug, make sure that you have discussed with your doctor about the risks and benefits of using the drug. Only use this medication if the benefits outweigh the risks.

Interaction

What medicines can interact with Pratifar?

Although certain drugs should not be taken at the same time, in some cases, two different drugs can be used together even if the interaction is possible. If this happens, your doctor may change the dose, or take other precautions if necessary.

Pratifar can interact with more than 250 types of drugs. The following are medicines that should be avoided to take together with Pratifar or its main active ingredient, famotidine, as interactions that occur can increase the side effects of the drug or change the way the drug works in the body. Among them:

• Atazanavir
• Dasatinib
• Neratinib
• Pazopanib
• Rilpivirine
• Siponimod
• Tizanidine

While other medicines that can interact with pratifar may increase the risk of side effects, in some cases it is the best treatment for you. These drugs include:

• Adenosine
• Amitriptyline
• Apalutamide
• Bacampicillin
• Bedaquiline
• Cefditoren
• Cefuroxime
• Chloroquine
• Efavirenz
• Entecavir
• Fesoterodine
• Fingolimod
• Galantamine
• Gatifloxacin
• Halofantrine
• Halothane

What foods and alcohol can interact with the pratative?

Certain medications should not be consumed at mealtimes or when eating certain types of food because interactions may occur. Consuming alcohol or tobacco-derived products with certain drugs can also cause interactions. Discuss with your health care professional the use of drugs with food, alcohol, or products derived from tobacco.

What health conditions can interact with pratifar?

There are several health conditions you may have that can interact with pratitis, including:

• Gastrointestinal bleeding, or bleeding that occurs in the digestive tract.
• A malfunctioning kidney

Overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, contact the local emergency services provider (118/119) or immediately to the nearest hospital emergency department.

What should I do if I miss a dose?

If you have missed a dose, take that dose immediately. But if it is time to take the next dose, skip the missed dose and take the dose as scheduled. Do not use multiple doses as this cannot guarantee that you will get well sooner.