Allylestrenol: functions, dosage, side effects, how to use it

What medicine is Allylestrenol?

What does allylestrenol do?

Allylestrenol is a synthetic (artificial) progestogen that is prescribed to treat a variety of health conditions occurring during pregnancy.

This drug can be used to prevent miscarriage, prevent premature birth, prevent habitual abortion, or a miscarriage that has occurred more than three or more times.

In addition, this drug can also be used to treat intrauterine growth retardation, in which the fetus does not grow at a normal rate.

Allylestrenol can also be used to treat conditions where the embryo cannot implant in the uterus. This medicine can also be used to help pregnant women give birth to healthy babies.

This drug is widely circulated in Europe, Japan, Hong Kong, India, Bangladesh, countries in Southeast Asia, including Indonesia. Even so, the use of this drug tends to be limited and not easy to find.

How is allylestrenol used?

Take this medication according to the instructions given by your doctor. You can take this drug with or without food. If you are worried that you will feel nauseous, you can take this drug to prevent it.

Follow all directions on the packaging of this medicine. If any information is unclear or you are unsure about any information, consult your pharmacist and doctor.

Tell your doctor if your condition doesn't change, gets worse, or if new symptoms develop. If you think you may have a serious medical problem, seek medical help right away.

Follow the rules given by your doctor or pharmacist before starting treatment. If you have any questions, consult your doctor or pharmacist.

How to store allylestrenol?

This medication is best stored at room temperature and out of direct sunlight. In addition, keep it away from damp places. Always try to store it in a dry place.

Do not store this drug in the bathroom and do not freeze it. Pay attention to any instructions that appear on the packaging of medicinal products, or ask a pharmacist if you have any doubts.

Keep this medication out of reach of children and pets. Do not flush this medication down the toilet or drain, unless instructed to do so by your doctor, pharmacist, or other health care professional.

To understand proper disposal practices, consult your local waste disposal agency or ask your doctor.

Allylestrenol dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the allylestrenol dosage for adults?

Intrauterine growth retardation

To treat intraunterine growth retardation, take one tablet taken three times a day for about two months. The dose can be reduced if the condition improves.

Threatened with a miscarriage

One 5 mg tablet, taken three times a day for 5-7 consecutive days or until symptoms disappear.

Threatened with premature birth

The dosage used to prevent preterm birth can be adjusted according to each condition. The maximum daily dose is 40 mg.

What is the allylestrenol dosage for children?

The dosage for children has not been determined. Consult your doctor for more information. However, this medicine should not be used by children under 16 years of age.

In what dosage is allylestrenol available?

Allylestrenol is available in 5 mg tablets.

Allylestrenol side effects

What side effects can be experienced due to allylestrenol?

Side effects that can occur after taking this drug include:

• Indigestion
• Change in appetite / weight
• Fluid retention
• Edema
• Acne
• Skin rash
• Urticaria
• Depression
• Headache
• Fever
• Fatigue
• Breast changes
• Hirsutism
• Changes in libido
• Changed menstrual cycles or irregular menstrual bleeding (rare).

Even so, not everyone who takes this drug experiences the side effects listed above. There may be other side effects which are not mentioned above and experienced by people taking this medicine.

If you have concerns about certain side effects, consult your doctor or pharmacist with further questions about drugs and side effects that may arise from using this drug.

Allylestrenol Drug Warnings and Cautions

What should be known before using allylestrenol?

Before using allylestrenol, you must pay attention to the following things:

• Tell your doctor and pharmacist if you are allergic to this drug. This drug should not be used by those of you who have allergies to the drug allylestrenol.
• Tell your doctor and pharmacist about prescription and nonprescription drugs, vitamins, nutritional supplements, and herbal products that you are currently using or will be using
• Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding
• This medicine should not be used by those of you who have had an abortion but it was not complete.
• This medicine should not be used if you have serious enough liver disease, because if you continue to use it, it could increase your risk or adverse effects.
• This medicine should not be used if you have carcinoma or hormone-dependent tumors, as they may worsen your health condition.
• Allylestrenol should not be used if you have thrombophlebitis or inflammation of the blood vessels, as this can make your condition worse.
• Allylestrenol should not be used if you have an acute brain because it can increase the negative effects and your health condition.

Is allylestrenol safe for pregnant and lactating women?

This drug is designed to be consumed while pregnant. Therefore, this drug is safe to consume while pregnant. However, different effects can appear in nursing mothers.

Use can be stopped after pregnancy because it can affect the health of the baby who is still breastfeeding. Therefore, breastfeeding mothers are not recommended to take this drug because it can have an effect on the baby who is breastfed.

There is no adequate research on the risks of using this drug in pregnant or breastfeeding women. Always consult your doctor to weigh the potential benefits and risks before using this medication. This drug is included in the risk of pregnancy category C according to the US Food and Drug Administration (FDA).

The following references the pregnancy risk categories according to the FDA:

• A = Not at risk
• B = No risk in several studies
• C = May be risky
• D = There is positive evidence of risk
• X = Contraindicated
• N = Unknown

Allylestrenol Drug Interactions

What other medicines may interact with allylestrenol?

Interactions that occur between this drug and other drugs can change the performance of this drug or increase the risk of serious side effects from this drug or other drugs you are taking. However, not all possible drug interactions are listed in this article.

Keep a list of all the products you use (including prescription / non-prescription drugs and herbal products) and consult your doctor or pharmacist. Do not start, stop, or change the dose of any medication without your doctor's approval.

There are 1,848 drugs that may interact with allylestrenol, but not all of them have harmful effects. Among the drugs that can interact with allylestrenol are:

• Abatacept. The metabolism of this drug may increase if it interacts with abatacept.
• Acarbose. Acarbose can reduce the excretion rate of allylestrenol, thereby increasing serum levels higher.
• Aceclofenac. This drug can reduce the excretion level of allyslestrenol, thereby increasing serum levels higher.
• Acemetacin. This drug can reduce the excretion level of allyslestrenol, thereby increasing serum levels higher.
• Carbamazepine. Metabolism from this drug may decrease when interacting with allylestrenol.
• Chondoritin Sulfate. Allylestrenol can reduce the excretion rate of this drug, thereby increasing serum levels higher.
• Chromic Chloride. Allylestrenol can reduce the excretion rate of this drug, thereby increasing serum levels higher.
• Phenobarbital. Metabolism of allylestrenol may increase when interacting with phenobarbital.
• Phenytoin. Phenytoin metabolism may decrease when interacting with phenytoin.
• Griseofulvin. Allylestrenol metabolism can increase when interacting with griseofulvin.
• Ketoconazole. Allylestrenol metabolism may decrease if interacting with this drug.
• Rifampin. Metabolism from this drug may decrease if it interacts with allylestrenol.

Can food or alcohol interact with allylestrenol?

Certain drugs should not be taken at the same time as meals or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur.

Even so, there has not been found evidence to suggest an alcohol interaction with this drug. However, remain vigilant by limiting alcohol use while taking this drug.

Discuss using this medication with food, alcohol, or tobacco with your health care provider to avoid more serious health problems.

What health conditions may interact with allylestrenol?

Any other health conditions you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

• Migraine and embolic disorders
• Epilepsy
• Migraine
• Asthma
• Sinusitis
• Heart dysfunction
• Glucose tolerance
• Diabetes
• Kidney dysfunction. This medicine can increase the adverse effects on those of you who have a history of kidney disease. In fact, treatment should be stopped if your condition gets worse.
• Loss of sight. If you suddenly lose vision, develop swelling of the eyelids, or have double vision, you should immediately stop using this drug.
• History of depression. If you have had depression before, you should monitor any changes in your mood while taking this medicine. This medicine should be replaced with another, safer alternative.

Allylestrenol overdose

What should I do in an emergency or overdose?

In case of an emergency or overdose, immediately contact the local emergency service provider (118/119) or immediately to the emergency room at the nearest hospital.

What should I do if I miss a dose?

If you forget a dose of this medicine, take the missed dose as soon as possible. However, when the time indicates that it is time to take the next dose, skip the missed dose and take this medication on the usual dosing schedule.

Do not insist on taking more than one dose at a time, and do not intentionally double the dose because the use of the drug in the wrong dosage can endanger your health condition.

Hello Health Group does not provide medical advice, diagnosis or treatment.